Ceramide, Cell biology, Sphingomyelin, Lipid signaling and Signal transduction are his primary areas of study. His Ceramide study is related to the wider topic of Apoptosis. His study brings together the fields of Mitochondrial intermembrane space and Cell biology.
Sphingomyelin is a subfield of Biochemistry that Richard Kolesnick studies. His studies in Lipid signaling integrate themes in fields like Tumor necrosis factor alpha, Caspase and Sphingolipid. Specifically, his work in Signal transduction is concerned with the study of Second messenger system.
Richard Kolesnick mainly investigates Ceramide, Cell biology, Sphingomyelin, Biochemistry and Apoptosis. His work deals with themes such as Sphingolipid, Signal transduction, Second messenger system and Lipid signaling, which intersect with Ceramide. Richard Kolesnick interconnects Caspase, Caenorhabditis elegans and Cell membrane in the investigation of issues within Cell biology.
He works mostly in the field of Sphingomyelin, limiting it down to concerns involving Protein kinase A and, occasionally, Phosphatidylcholine. His Apoptosis research is multidisciplinary, relying on both Molecular biology and Cancer research. His biological study deals with issues like Internal medicine, which deal with fields such as Oncology.
Richard Kolesnick spends much of his time researching Cancer research, Stem cell, Acid sphingomyelinase, Ceramide and Sphingomyelin. His Stem cell study incorporates themes from Intestinal epithelium, LGR5, Immunology and Organoid. His Acid sphingomyelinase research includes elements of Angiogenesis, Infiltration, Pharmacology and Ischemia.
The concepts of his Ceramide study are interwoven with issues in Inflammation, Citrobacter rodentium, Lipid signaling, Mediator and Western blot. His Sphingomyelin research is multidisciplinary, incorporating perspectives in Signal transduction, Cell biology and Liposome. His Cell biology study is mostly concerned with Sphingolipid and Second messenger system.
Cancer research, Stem cell, Immunology, Sphingomyelin and Cell biology are his primary areas of study. His Cancer research study which covers Radiation therapy that intersects with Endothelial stem cell, Sensitization and Monoclonal antibody. His study on Stem cell also encompasses disciplines like
His studies in Sphingomyelin integrate themes in fields like Ceramide, Signal transduction and Lipid signaling. His Ceramide study is concerned with the larger field of Biochemistry. His work carried out in the field of Cell biology brings together such families of science as Phenotype, Multiple drug resistance and Downregulation and upregulation.
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Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.
Marcel Verheij;Marcel Verheij;Ron Bose;Xin Hua Lin;Bei Yao.
The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling
Richard Kolesnick;David W. Golde.
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis.
A. Haimovitz-Friedman;Chu-Cheng Kan;D. Ehleiter;R. S. Persaud.
Journal of Experimental Medicine (1994)
REGULATION OF CERAMIDE PRODUCTION AND APOPTOSIS
Richard N. Kolesnick;Martin Krönke.
Annual Review of Physiology (1998)
Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
Ron Bose;Marcel Verheij;Adriana Haimovitz-Friedman;Kathleen Scotto.
Signal Transduction of Stress via Ceramide
Shalini Mathias;Louis A. Peña;Richard N. Kolesnick.
Biochemical Journal (1998)
Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration
Caroline A. Lindemans;Caroline A. Lindemans;Marco Calafiore;Anna M. Mertelsmann;Margaret H. O'Connor.
Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy.
Yutaka Morita;Gloria I. Perez;Francois Paris;Silvia R. Miranda.
Nature Medicine (2000)
CD95 signaling via ceramide-rich membrane rafts.
Heike Grassme;Andreas Jekle;Andrea Riehle;Heinz Schwarz.
Journal of Biological Chemistry (2001)
Signal transduction through lipid second messengers
Sarah Spiegel;David Foster;Richard Kolesnick.
Current Opinion in Cell Biology (1996)
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