D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 89 Citations 39,157 222 World Ranking 1607 National Ranking 921

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Enzyme

Ceramide, Cell biology, Sphingomyelin, Lipid signaling and Signal transduction are his primary areas of study. His Ceramide study is related to the wider topic of Apoptosis. His study brings together the fields of Mitochondrial intermembrane space and Cell biology.

Sphingomyelin is a subfield of Biochemistry that Richard Kolesnick studies. His studies in Lipid signaling integrate themes in fields like Tumor necrosis factor alpha, Caspase and Sphingolipid. Specifically, his work in Signal transduction is concerned with the study of Second messenger system.

His most cited work include:

  • Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. (1660 citations)
  • The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling (848 citations)
  • Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. (803 citations)

What are the main themes of his work throughout his whole career to date?

Richard Kolesnick mainly investigates Ceramide, Cell biology, Sphingomyelin, Biochemistry and Apoptosis. His work deals with themes such as Sphingolipid, Signal transduction, Second messenger system and Lipid signaling, which intersect with Ceramide. Richard Kolesnick interconnects Caspase, Caenorhabditis elegans and Cell membrane in the investigation of issues within Cell biology.

He works mostly in the field of Sphingomyelin, limiting it down to concerns involving Protein kinase A and, occasionally, Phosphatidylcholine. His Apoptosis research is multidisciplinary, relying on both Molecular biology and Cancer research. His biological study deals with issues like Internal medicine, which deal with fields such as Oncology.

He most often published in these fields:

  • Ceramide (47.06%)
  • Cell biology (38.73%)
  • Sphingomyelin (30.39%)

What were the highlights of his more recent work (between 2013-2021)?

  • Cancer research (21.57%)
  • Stem cell (14.71%)
  • Acid sphingomyelinase (20.59%)

In recent papers he was focusing on the following fields of study:

Richard Kolesnick spends much of his time researching Cancer research, Stem cell, Acid sphingomyelinase, Ceramide and Sphingomyelin. His Stem cell study incorporates themes from Intestinal epithelium, LGR5, Immunology and Organoid. His Acid sphingomyelinase research includes elements of Angiogenesis, Infiltration, Pharmacology and Ischemia.

The concepts of his Ceramide study are interwoven with issues in Inflammation, Citrobacter rodentium, Lipid signaling, Mediator and Western blot. His Sphingomyelin research is multidisciplinary, incorporating perspectives in Signal transduction, Cell biology and Liposome. His Cell biology study is mostly concerned with Sphingolipid and Second messenger system.

Between 2013 and 2021, his most popular works were:

  • Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration (456 citations)
  • A rectal cancer organoid platform to study individual responses to chemoradiation. (75 citations)
  • C16:0-Ceramide Signals Insulin Resistance (52 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Enzyme

Cancer research, Stem cell, Immunology, Sphingomyelin and Cell biology are his primary areas of study. His Cancer research study which covers Radiation therapy that intersects with Endothelial stem cell, Sensitization and Monoclonal antibody. His study on Stem cell also encompasses disciplines like

  • Intestinal epithelium which is related to area like Interferon, Programmed cell death, Immune system, T cell and Interleukin 22,
  • Regeneration and Innate lymphoid cell most often made with reference to Paneth cell.

His studies in Sphingomyelin integrate themes in fields like Ceramide, Signal transduction and Lipid signaling. His Ceramide study is concerned with the larger field of Biochemistry. His work carried out in the field of Cell biology brings together such families of science as Phenotype, Multiple drug resistance and Downregulation and upregulation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

Marcel Verheij;Marcel Verheij;Ron Bose;Xin Hua Lin;Bei Yao.
Nature (1996)

2240 Citations

The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling

Richard Kolesnick;David W. Golde.
Cell (1994)

1343 Citations

Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis.

A. Haimovitz-Friedman;Chu-Cheng Kan;D. Ehleiter;R. S. Persaud.
Journal of Experimental Medicine (1994)

1297 Citations

REGULATION OF CERAMIDE PRODUCTION AND APOPTOSIS

Richard N. Kolesnick;Martin Krönke.
Annual Review of Physiology (1998)

1152 Citations

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

Ron Bose;Marcel Verheij;Adriana Haimovitz-Friedman;Kathleen Scotto.
Cell (1995)

1056 Citations

Signal Transduction of Stress via Ceramide

Shalini Mathias;Louis A. Peña;Richard N. Kolesnick.
Biochemical Journal (1998)

993 Citations

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

Caroline A. Lindemans;Caroline A. Lindemans;Marco Calafiore;Anna M. Mertelsmann;Margaret H. O'Connor.
Nature (2015)

740 Citations

Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy.

Yutaka Morita;Gloria I. Perez;Francois Paris;Silvia R. Miranda.
Nature Medicine (2000)

699 Citations

CD95 signaling via ceramide-rich membrane rafts.

Heike Grassme;Andreas Jekle;Andrea Riehle;Heinz Schwarz.
Journal of Biological Chemistry (2001)

698 Citations

Signal transduction through lipid second messengers

Sarah Spiegel;David Foster;Richard Kolesnick.
Current Opinion in Cell Biology (1996)

650 Citations

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