D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 99 Citations 33,340 396 World Ranking 723 National Ranking 53

Research.com Recognitions

Awards & Achievements

2011 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Physiology and Pharmacology/Toxicology

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Internal medicine

Erich Gulbins mainly investigates Cell biology, Ceramide, Acid sphingomyelinase, Apoptosis and Signal transduction. The Cell biology study combines topics in areas such as Fas receptor and Cell, Biochemistry, Cell membrane. His Ceramide research incorporates elements of Receptor, Lipid signaling, Sphingomyelin, Sphingolipid and Pharmacology.

His work carried out in the field of Acid sphingomyelinase brings together such families of science as Cell signaling, Acid Ceramidase, Immunology, Enzyme and Sphingomyelin phosphodiesterase. His work focuses on many connections between Immunology and other disciplines, such as Cystic fibrosis, that overlap with his field of interest in Inflammation. His Apoptosis study combines topics from a wide range of disciplines, such as Phospholipid scrambling, Mitochondrion, Microbiology and Sepsis.

His most cited work include:

  • Functional Significance of Cell Volume Regulatory Mechanisms (1600 citations)
  • CD95 signaling via ceramide-rich membrane rafts. (537 citations)
  • Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts. (448 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Ceramide, Cell biology, Acid sphingomyelinase, Apoptosis and Immunology. His Ceramide study integrates concerns from other disciplines, such as Sphingosine, Sphingolipid, Cystic fibrosis and Sphingomyelin. His Cystic fibrosis research includes elements of Pseudomonas aeruginosa, Inflammation, Lung and Pathology.

The study incorporates disciplines such as Receptor, Jurkat cells and Cell membrane in addition to Cell biology. His Acid sphingomyelinase research incorporates themes from Amitriptyline, Pharmacology and Sphingomyelin phosphodiesterase. His study looks at the relationship between Apoptosis and fields such as Mitochondrion, as well as how they intersect with chemical problems.

He most often published in these fields:

  • Ceramide (52.83%)
  • Cell biology (37.74%)
  • Acid sphingomyelinase (42.64%)

What were the highlights of his more recent work (between 2018-2021)?

  • Ceramide (52.83%)
  • Acid sphingomyelinase (42.64%)
  • Sphingolipid (20.19%)

In recent papers he was focusing on the following fields of study:

Erich Gulbins spends much of his time researching Ceramide, Acid sphingomyelinase, Sphingolipid, Sphingosine and Pharmacology. His Ceramide research is multidisciplinary, incorporating elements of Inflammation, Enzyme, Neuroscience and Cell biology. His Cell biology research incorporates elements of Endocytosis, Ion channel and Cytosol.

His work in Acid sphingomyelinase addresses issues such as Depression, which are connected to fields such as Quality of life, Blood lipids and Pathophysiology. His Sphingolipid study integrates concerns from other disciplines, such as Sphingosine-1-phosphate, Cell signaling, Addiction and Serotonergic. Erich Gulbins interconnects Cystic fibrosis, Microbiology, Pseudomonas aeruginosa, Bacteria and Lung in the investigation of issues within Sphingosine.

Between 2018 and 2021, his most popular works were:

  • Specific Inhibition of the NLRP3 Inflammasome as an Antiinflammatory Strategy in Cystic Fibrosis (31 citations)
  • Pharmacological inhibition of acid sphingomyelinase prevents uptake of SARS-CoV-2 by epithelial cells. (18 citations)
  • Pharmacological inhibition of acid sphingomyelinase prevents uptake of SARS-CoV-2 by epithelial cells. (18 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His primary areas of study are Ceramide, Acid sphingomyelinase, Sphingosine, Sphingolipid and Cell biology. The various areas that Erich Gulbins examines in his Ceramide study include Downregulation and upregulation, Pharmacology, In vivo and Enzyme. His Acid sphingomyelinase research integrates issues from Vesicular stomatitis virus, Quality of life and Neutralization.

Erich Gulbins has included themes like Pseudomonas aeruginosa, Lung, Microbiology and Biofilm in his Sphingosine study. His research in Sphingolipid intersects with topics in Serine C-palmitoyltransferase, Endoplasmic reticulum, De novo synthesis and Escherichia coli. His Cell biology study incorporates themes from Sphingomyelin phosphodiesterase 1, Phospholipidosis, Knockout mouse and Lysosome.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Functional Significance of Cell Volume Regulatory Mechanisms

Florian Lang;Gillian L. Busch;Markus Ritter;Harald Völkl.
Physiological Reviews (1998)

2059 Citations

CD95 signaling via ceramide-rich membrane rafts.

Heike Grassme;Andreas Jekle;Andrea Riehle;Heinz Schwarz.
Journal of Biological Chemistry (2001)

698 Citations

Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts.

H. Grassmé;V. Jendrossek;A. Riehle;G. von Kürthy.
Nature Medicine (2003)

687 Citations

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

Volker Teichgräber;Martina Ulrich;Nicole Endlich;Joachim Riethmüller.
Nature Medicine (2008)

546 Citations

Raft ceramide in molecular medicine

Erich Gulbins;Richard Kolesnick.
Oncogene (2003)

538 Citations

Ceramide Enables Fas to Cap and Kill

Aida Cremesti;François Paris;Heike Grassmé;Nils Holler.
Journal of Biological Chemistry (2001)

490 Citations

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway.

Erich Gulbins;Reid Bissonnette;Artin Mahboubi;Seamus Martin.
Immunity (1995)

472 Citations

Liver cell death and anemia in Wilson disease involve acid sphingomyelinase and ceramide.

Philipp A Lang;Marcus Schenck;Jan P Nicolay;Jan Ulrich Becker.
Nature Medicine (2007)

464 Citations

Fas- or Ceramide-induced Apoptosis Is Mediated by a Rac1-regulated Activation of Jun N-terminal Kinase/p38 Kinases and GADD153

Birgit Brenner;Ursula Koppenhoefer;Christoph Weinstock;Otwin Linderkamp.
Journal of Biological Chemistry (1997)

441 Citations

Ceramide-enriched membrane domains.

Claudia R. Bollinger;Volker Teichgräber;Erich Gulbins.
Biochimica et Biophysica Acta (2005)

394 Citations

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