World's Best Scientists 2026 revealed!
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Biology and Biochemistry
USA
2026
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Chemistry
USA
2026

D-Index & Metrics

Chemistry

D-Index
151
Citations
86097
World Ranking
128
National Ranking
65

Biology and Biochemistry

D-Index
161
Citations
96617
World Ranking
123
National Ranking
93

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2026 - Research.com Chemistry in United States Leader Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Chemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2004 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Yusuf A. Hannun is affiliated with Stony Brook University in the United States and has a prolific publication record in the fields of Biochemistry, Genetics, and Molecular Biology, with a significant number of works also categorized under Medicine. Their research spans several subfields, including Molecular Biology, Cell Biology, Immunology, Physiology, and Epidemiology.

The primary topics explored in their work include:

  • Sphingolipid Metabolism and Signaling
  • Lipid Membrane Structure and Behavior
  • Cellular Transport and Secretion
  • Immune Cells in Cancer
  • Endoplasmic Reticulum Stress and Disease
  • Lysosomal Storage Disorders Research
  • Erythrocyte Function and Pathophysiology

Their frequent coauthors are:

  • Lina M. Obeid (28 collaborations)
  • Ashley J. Snider (18 collaborations)
  • Chiara Luberto (15 collaborations)
  • Daniel Canals (12 collaborations)
  • Fahd Al-Mulla (12 collaborations)

Yusuf A. Hannun has published widely in various scientific journals. The most common publication venues include:

  • Journal of Lipid Research (9 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (7 publications)
  • The FASEB Journal (6 publications)
  • The Journal of Immunology (2 publications)
  • The EMBO Journal (2 publications)

Significant recent papers authored or coauthored by Yusuf A. Hannun include:

  • Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice, 2020, Science Translational Medicine
  • Asah2 Represses the p53-Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis, 2021, The Journal of Immunology
  • Group IIA secreted phospholipase A2 is associated with the pathobiology leading to COVID-19 mortality, 2021, Journal of Clinical Investigation
  • Golgi maturation-dependent glycoenzyme recycling controls glycosphingolipid biosynthesis and cell growth via GOLPH3, 2021, The EMBO Journal
  • Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis, 2021, Cell Death and Disease

The scientist has been recognized with awards such as the Fellow of the American Association for the Advancement of Science (AAAS) in 2004 and membership in the Association of American Physicians.

Best Publications

  • Principles of bioactive lipid signalling: lessons from sphingolipids

    Yusuf A. Hannun;Lina M. Obeid;Lina M. Obeid

  • Programmed cell death induced by ceramide

    Lina M. Obeid;Corinne M. Linardic;Linda A. Karolak;Yusuf A. Hannun

  • Functions of Ceramide in Coordinating Cellular Responses to Stress

    Yusuf A. Hannun

  • Sphingolipids and their metabolism in physiology and disease.

    Yusuf A. Hannun;Lina M. Obeid;Lina M. Obeid

  • The sphingomyelin cycle and the second messenger function of ceramide

    Y A Hannun

  • Functions of sphingolipids and sphingolipid breakdown products in cellular regulation

    Yusuf A. Hannun;Robert M. Bell

  • Biologically active sphingolipids in cancer pathogenesis and treatment.

    Besim Ogretmen;Yusuf A. Hannun

  • Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets

    Y A Hannun;C R Loomis;A H Merrill;R M Bell

  • An overview of sphingolipid metabolism: from synthesis to breakdown.

    Christopher R. Gault;Lina M. Obeid;Yusuf A. Hannun

  • The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind.

    Yusuf A. Hannun;Lina M. Obeid

  • Ceramide in the eukaryotic stress response

    Yusuf A. Hannun;Chiara Luberto

  • Apoptosis and the Dilemma of Cancer Chemotherapy

    Yusuf A. Hannun

  • Ceramide in apoptosis: an overview and current perspectives.

    Benjamin J. Pettus;Charles E. Chalfant;Yusuf A. Hannun

  • The complex life of simple sphingolipids

    Anthony H Futerman;Yusuf A Hannun

  • Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation.

    T Okazaki;R M Bell;Y A Hannun

  • Bioactive sphingolipids: metabolism and function

    Nana Bartke;Yusuf A. Hannun

  • Substantial contribution of extrinsic risk factors to cancer development

    Song Wu;Sarah E Powers;Wenquan Zhu;Yusuf A. Hannun

  • Ceramide activates heterotrimeric protein phosphatase 2A.

    R T Dobrowsky;C Kamibayashi;M C Mumby;Y A Hannun

  • Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation.

    Mie-Young Kim;C. Linardic;L. Obeid;Y. Hannun

  • CERAMIDE : AN INTRACELLULAR SIGNAL FOR APOPTOSIS

    Yusuf A. Hannun;Lina M. Obeid

Frequent Co-Authors

Lina M. Obeid
Lina M. Obeid Stony Brook University
Jacek Bielawski
Jacek Bielawski Medical University of South Carolina
Alicja Bielawska
Alicja Bielawska Medical University of South Carolina
Besim Ogretmen
Besim Ogretmen Medical University of South Carolina
Charles E. Chalfant
Charles E. Chalfant Virginia Commonwealth University
Gerard C. Blobe
Gerard C. Blobe Duke University
Alfred H. Merrill
Alfred H. Merrill Georgia Institute of Technology
John R. Raymond
John R. Raymond Medical College of Wisconsin

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