Thierry Levade

Overview

Best Publications

• A Review of Gaucher Disease Pathophysiology, Clinical Presentation and Treatments

  Jérôme Stirnemann;Nadia Belmatoug;Fabrice Camou;Christine Serratrice

  678
  Citations

• Glutathione Regulation of Neutral Sphingomyelinase in Tumor Necrosis Factor-α-induced Cell Death

  Bin Liu;Nathalie Andrieu-Abadie;Thierry Levade;Ping Zhang

  433
  Citations

• Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis.

  J. P. Jaffrézou;T. Levade;A. Bettaïeb;N. Andrieu

  432
  Citations

• Signalling sphingomyelinases: which, where, how and why?

  Thierry Levade;Jean-Pierre Jaffrézou

  410
  Citations

• Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy

  Sophie Pattingre;Sophie Pattingre;Chantal Bauvy;Chantal Bauvy;Stéphane Carpentier;Thierry Levade

  380
  Citations

• Ceramide in apoptosis signaling: relationship with oxidative stress.

  Nathalie Andrieu-Abadie;Valérie Gouazé;Robert Salvayre;Thierry Levade

  368
  Citations

• Regulation of Autophagy by Sphingosine Kinase 1 and Its Role in Cell Survival during Nutrient Starvation

  Grégory Lavieu;Francesca Scarlatti;Giusy Sala;Stéphane Carpentier

  345
  Citations

• TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma.

  Florie Bertrand;Anne Montfort;Elie Marcheteau;Caroline Imbert

  332
  Citations

• Recommendations on the diagnosis and management of Niemann-Pick disease type C

  James E. Wraith;Matthias R. Baumgartner;Bruno Bembi;Athanasios Covanis

  289
  Citations

• The TNF Paradox in Cancer Progression and Immunotherapy.

  Anne Montfort;Céline Colacios;Céline Colacios;Thierry Levade;Thierry Levade;Nathalie Andrieu-Abadie

  259
  Citations

• L-carnitine prevents doxorubicin-induced apoptosis of cardiac myocytes: role of inhibition of ceramide generation

  Nathalie Andrieu-Abadie;Jean-Pierre Jaffrézou;Stéphane Hatem;Guy Laurent

  249
  Citations

• Apelin Treatment Increases Complete Fatty Acid Oxidation, Mitochondrial Oxidative Capacity, and Biogenesis in Muscle of Insulin-Resistant Mice

  Camille Attané;Camille Foussal;Sophie Le Gonidec;Alexandre Benani

  243
  Citations

• Sphingomyelin hydrolysis during apoptosis.

  Nathalie Andrieu-Abadie;Thierry Levade

  237
  Citations

• Role of Sphingosine 1-Phosphate in the Mitogenesis Induced by Oxidized Low Density Lipoprotein in Smooth Muscle Cells via Activation of Sphingomyelinase, Ceramidase, and Sphingosine Kinase

  Nathalie Augé;Mariana Nikolova-Karakashian;Stéphane Carpentier;Sampath Parthasarathy

  233
  Citations

• Sphingolipid Mediators in Cardiovascular Cell Biology and Pathology

  Thierry Levade;Nathalie Augé;Robert Jan Veldman;Olivier Cuvillier

  222
  Citations

• Overcoming MDR-associated chemoresistance in HL-60 acute myeloid leukemia cells by targeting sphingosine kinase-1.

  E Bonhoure;D Pchejetski;N Aouali;N Aouali;N Aouali;H Morjani

  219
  Citations

• Glutathione Peroxidase-1 Overexpression Prevents Ceramide Production and Partially Inhibits Apoptosis in Doxorubicin-Treated Human Breast Carcinoma Cells

  Valérie Gouazé;Marc-Edouard Mirault;Stéphane Carpentier;Robert Salvayre

  213
  Citations

• Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis.

  Julie Guillermet;Nathalie Saint-Laurent;Philippe Rochaix;Olivier Cuvillier

  184
  Citations

• Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria.

  Olivier Cuvillier;Thierry Levade

  183
  Citations

• Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicin-induced apoptosis of MCF7 breast adenocarcinoma cells.

  Olivier Cuvillier;V Nava;S K Murthy;L Edsall

  179
  Citations