World's Best Scientists 2026 revealed!
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Neuroscience
USA
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
146
Citations
86457
World Ranking
206
National Ranking
142

Neuroscience

D-Index
152
Citations
95643
World Ranking
142
National Ranking
94

Bryan L. Roth publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Bryan L. Roth sits on this spectrum.

38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientists 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38 publications 887+

This scientist: 680 publications — 98th percentile

98% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

Bryan L. Roth D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Bryan L. Roth sits on this spectrum.

30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30 D-Index 163+

This scientist: 152 D-Index — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Neuroscience in United States Leader Award

Overview

Bryan L. Roth is affiliated with the University of North Carolina at Chapel Hill in the United States and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their research output covers a broad spectrum of subfields, including molecular biology, cellular and molecular neuroscience, organic chemistry, clinical psychology, and pharmacology.

Their main topics of work encompass receptor mechanisms and signaling, neuropeptides and animal physiology, pharmacological receptor mechanisms and effects, chemical synthesis and alkaloids, neurotransmitter receptor influence on behavior, psychedelics and drug studies, as well as neuroscience and neuropharmacology research.

Frequent coauthors in their work include:

  • Xi-Ping Huang
  • Brian K. Shoichet
  • Jeffrey F. DiBerto
  • B. Krumm
  • Yongfeng Liu

They have published extensively in several venues, with notable frequent publication sources such as:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • OPAL (Open@LaTrobe) (La Trobe University)
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Nature

Recent papers authored or coauthored by Bryan L. Roth include:

  • "TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome," 2020, Nature Chemical Biology
  • "Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor," 2020, Cell
  • "Synthon-based ligand discovery in virtual libraries of over 11 billion compounds," 2021, Nature
  • "Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys," 2020, Nature Neuroscience
  • "Virtual discovery of melatonin receptor ligands to modulate circadian rhythms," 2020, Nature

Best Publications

  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

    David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu

  • Relating protein pharmacology by ligand chemistry

    Michael J. Keiser;Bryan L. Roth;Bryan L. Roth;Blaine N. Armbruster;Paul R Ernsberger

  • The Expanded Biology of Serotonin

    Miles Berger;John A. Gray;Bryan L. Roth

  • Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

    Blaine N. Armbruster;Xiang Li;Mark H. Pausch;Stefan Herlitze

  • DREADDs for Neuroscientists.

    Bryan L. Roth

  • Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression

    Grazyna Rajkowska;José J Miguel-Hidalgo;Jinrong Wei;Ginny Dilley

  • Predicting new molecular targets for known drugs

    Michael J. Keiser;Vincent Setola;John J. Irwin;Christian Laggner

  • Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

    Michael J. Krashes;Shuichi Koda;Chian Ping Ye;Sarah C. Rogan

  • Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia

    Bryan L. Roth;Douglas J. Sheffler;Wesley K. Kroeze

  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology

    Jonathan D. Urban;William P. Clarke;Mark Von Zastrow;David E. Nichols

  • Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology.

    David A. Shapiro;Sean Renock;Elaine Arrington;Louis A. Chiodo

  • Remote control of neuronal activity in transgenic mice expressing evolved G protein-coupled receptors.

    Georgia M. Alexander;Sarah C. Rogan;Atheir I. Abbas;Blaine N. Armbruster

  • Parkin-deficient Mice Exhibit Nigrostriatal Deficits but Not Loss of Dopaminergic Neurons

    Matthew S. Goldberg;Sheila M. Fleming;James J. Palacino;Carlos Cepeda

  • Structure of the human κ-opioid receptor in complex with JDTic

    Huixian Wu;Daniel Wacker;Mauro Mileni;Vsevolod Katritch

  • H1-Histamine Receptor Affinity Predicts Short-Term Weight Gain for Typical and Atypical Antipsychotic Drugs

    Wesley Kars Kroeze;Sandra J. Hufeisen;Beth A. Popadak;Sean M. Renock

  • Structure-based discovery of opioid analgesics with reduced side effects

    Aashish Manglik;Henry Lin;Dipendra K. Aryal;John D. McCorvy

  • Salvinorin A: A potent naturally occurring nonnitrogenous κ opioid selective agonist

    Bryan L. Roth;Karen Baner;Richard Westkaemper;Daniel Siebert

  • Ultra-large library docking for discovering new chemotypes

    Jiankun Lyu;Sheng Wang;Trent E. Balius;Isha Singh

  • Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.

    B L Roth;S C Craigo;M S Choudhary;A Uluer

  • Automated design of ligands to polypharmacological profiles

    Jérémy Besnard;Gian Filippo Ruda;Vincent Setola;Keren Abecassis

  • The promise and peril of chemical probes.

    Cheryl H. Arrowsmith;James E. Audia;Christopher Austin;Jonathan Baell

Frequent Co-Authors

Xi Ping Huang
Xi Ping Huang University of North Carolina at Chapel Hill
Richard A. Glennon
Richard A. Glennon Virginia Commonwealth University
Brian K. Shoichet
Brian K. Shoichet University of California, San Francisco
Jian Jin
Jian Jin Icahn School of Medicine at Mount Sinai
Vsevolod Katritch
Vsevolod Katritch University of Southern California
Raymond C. Stevens
Raymond C. Stevens University of Southern California
Jordan K. Zjawiony
Jordan K. Zjawiony University of Mississippi
Vadim Cherezov
Vadim Cherezov University of Southern California
William C. Wetsel
William C. Wetsel Duke University
Herbert Y. Meltzer
Herbert Y. Meltzer Northwestern University

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