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Chemistry

D-Index
78
Citations
22412
World Ranking
3790
National Ranking
1211

Overview

Richard A. Glennon is affiliated with Virginia Commonwealth University in the United States. Their research spans several interrelated fields, including neuroscience and psychology, with significant contributions to cellular and molecular neuroscience as well as clinical psychology. Their work also touches on organic chemistry, toxicology, and molecular biology.

The scientist's notable recent publications include:

  • 1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane (DOI): From an Obscure to Pivotal Member of the DOX Family of Serotonergic Psychedelic Agents - A Review, 2024, published in ACS Pharmacology & Translational Science
  • Investigation of the Optical Isomers of Methcathinone, and Two Achiral Analogs, at Monoamine Transporters and in Intracranial Self-Stimulation Studies in Rats, 2020, published in ACS Chemical Neuroscience
  • Functional characterization of N-octyl 4-methylamphetamine variants and related bivalent compounds at the dopamine and serotonin transporters using Ca2+ channels as sensors, 2021, published in Toxicology and Applied Pharmacology
  • Non-conserved residues dictate dopamine transporter selectivity for the potent synthetic cathinone and psychostimulant MDPV, 2021, published in Neuropharmacology
  • A strategy to prioritize emerging drugs of abuse for analysis: Abuse liability testing using intracranial self-stimulation (ICSS) in rats and validation with α-pyrrolidinohexanophenone (α-PHP), 2021, published in Emerging Trends in Drugs Addictions and Health

Their research primarily explores topics such as:

  • Neurotransmitter Receptor Influence on Behavior
  • Psychedelics and Drug Studies
  • Chemical synthesis and alkaloids
  • Forensic Toxicology and Drug Analysis
  • Neuroscience and Neuropharmacology Research
  • Receptor Mechanisms and Signaling
  • Nicotinic Acetylcholine Receptors Study

Frequent coauthors in their work include:

  • Małgorzata Dukat
  • José M. Eltit
  • Vy Nguyen
  • Rachel A. Davies
  • Tyson R. Baird

Richard A. Glennon has published multiple papers in several prominent scientific venues. The most common publication outlets are:

  • ACS Pharmacology & Translational Science
  • ACS Chemical Neuroscience
  • Neuropharmacology
  • Toxicology and Applied Pharmacology
  • Emerging Trends in Drugs Addictions and Health

Best Publications

  • Predicting new molecular targets for known drugs

    Michael J. Keiser;Vincent Setola;John J. Irwin;Christian Laggner

  • Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents

    Richard A. Glennon;Milt Titeler;J.D. McKenney

  • Central serotonin receptors as targets for drug research.

    Richard A. Glennon

  • Radioligand binding evidence implicates the brain 5-HT2 receptor as a site of action for LSD and phenylisopropylamine hallucinogens

    M. Titeler;R. A. Lyon;R. A. Glennon

  • 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) Induces Fenfluramine-Like Proliferative Actions on Human Cardiac Valvular Interstitial Cells in Vitro

    Vincent Setola;Sandra J. Hufeisen;K. Jane Grande-Allen;Ivan Vesely

  • Do functional relationships exist between 5-HT1A and 5-HT2 receptors?

    Nissar A. Darmani;Billy R. Martin;U. Pandey;Richard A. Glennon

  • Sigma receptor ligands and the use thereof

    Richard A. Glennon

  • Serotonin receptors: Clinical implications

    Richard A. Glennon

  • Binding of beta-carbolines and related agents at serotonin (5-HT(2) and 5-HT(1A)), dopamine (D(2)) and benzodiazepine receptors.

    Richard A. Glennon;Malgorzata Dukat;Brian Grella;Seoung-Soo Hong

  • NAN-190: an arylpiperazine analog that antagonizes the stimulus effects of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT).

    Richard A. Glennon;Noreen A. Naiman;M.Edward Pierson;M. Titeler

  • Autoradiographic characterization of (+-)-1-(2,5-dimethoxy-4-[125I] iodophenyl)-2-aminopropane ([125I]DOI) binding to 5-HT2 and 5-HT1c receptors in rat brain.

    N M Appel;W M Mitchell;R K Garlick;R A Glennon

  • Antagonism of the effects of the hallucinogen DOM and the purported 5-HT agonist quipazine by 5-HT2 antagonists.

    Richard A. Glennon;Richard Young;John A. Rosecrans

  • Higher-End Serotonin Receptors: 5-HT5, 5-HT6, and 5-HT7

    Richard A. Glennon

  • Antinociceptive Responses to Nicotinic Acetylcholine Receptor Ligands after Systemic and Intrathecal Administration in Mice

    M. I. Damaj;M. Fei-Yin;M. Dukat;W. Glassco

  • In vitro characterization of ephedrine-related stereoisomers at biogenic amine transporters and the receptorome reveals selective actions as norepinephrine transporter substrates.

    Richard B. Rothman;Nga Vu;John S. Partilla;Bryan L. Roth

  • 2-Substituted Tryptamines: Agents with Selectivity for 5-HT6 Serotonin Receptors |

    Richard A. Glennon;Mase Lee;Jagadeesh B. Rangisetty;Malgorzata Dukat

  • Structural features important for sigma 1 receptor binding.

    Richard A. Glennon;Seth Y. Ablordeppey;Abd M. Ismaiel;Mahmoud B. El-Ashmawy

  • Ketanserin analogues: structure-affinity relationships for 5-HT2 and 5-HT1C serotonin receptor binding.

    Jeff L. Herndon;Abd Ismaiel;Stacy P. Ingher;M. Teitler

  • Do classical hallucinogens act as 5-HT2 agonists or antagonists?

    Glennon Ra

  • 5-HT1 and 5-HT2 binding properties of derivatives of the hallucinugen 1-(2,5-dimethoxyphenyl)-2-aminopropane (2,5-DMA)

    Michael Shannon;George Battaglia;Richard A. Glennon;Milt Titeler

Frequent Co-Authors

Bryan L. Roth
Bryan L. Roth University of North Carolina at Chapel Hill
Billy R. Martin
Billy R. Martin Virginia Commonwealth University
Michael H. Baumann
Michael H. Baumann National Institute on Drug Abuse
Lemont B. Kier
Lemont B. Kier Virginia Commonwealth University
Richard B. Rothman
Richard B. Rothman National Institute on Drug Abuse
John W. Daly
John W. Daly National Institutes of Health
David J. Nutt
David J. Nutt Imperial College London
Javier González-Maeso
Javier González-Maeso Virginia Commonwealth University
Michael A. Sutton
Michael A. Sutton University of Michigan–Ann Arbor
Linda P. Dwoskin
Linda P. Dwoskin University of Kentucky

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