World's Best Scientists 2026 revealed!
George K. Aghajanian

George K. Aghajanian

D-Index & Metrics

Neuroscience

D-Index
145
Citations
71346
World Ranking
175
National Ranking
113

Medicine

D-Index
145
Citations
71346
World Ranking
1389
National Ranking
811

Research.com Recognitions

  • 2000 - Member of the National Academy of Medicine (NAM)

Overview

George K. Aghajanian was affiliated with Yale University in the United States. Their research mainly focused on the field of neuroscience, particularly emphasizing pharmacology, biological psychiatry, and cellular and molecular neuroscience as subfields.

The scientist contributed to the study of major topics including:

  • Treatment of Major Depression
  • Tryptophan and brain disorders
  • Neuroscience and Neuropharmacology Research

The body of their work included publications in well-regarded venues such as Biological Psychiatry and Neuropsychopharmacology. These publication venues each featured one of their recent papers.

Recent papers by George K. Aghajanian included:

  • Neurobiology of the Rapid-Acting Antidepressant Effects of Ketamine: Impact and Opportunities, 2020, published in Biological Psychiatry
  • Torgny Svensson, M.D., Ph.D. (1945-2020), 2020, published in Neuropsychopharmacology

The frequent co-authors who collaborated with George K. Aghajanian encompassed:

  • Ryota Shinohara
  • Chadi G. Abdallah
  • Aleksander A. Mathé
  • Elias Eriksson
  • John H. Krystal

During their career, George K. Aghajanian was recognized as a Member of the National Academy of Medicine (NAM) in the year 2000.

Best Publications

  • mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

    Nanxin Li;Boyoung Lee;Rongjian Liu;Mounira Banasr

  • Molecular and Cellular Basis of Addiction

    Eric J. Nestler;George K. Aghajanian

  • Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

    Ronald S Duman;George K Aghajanian;Gerard Sanacora;John H Krystal

  • DOPAMINERGIC NEURONS: EFFECT OF ANTIPSYCHOTIC DRUGS AND AMPHETAMINE ON SINGLE CELL ACTIVITY

    Benjamin S. Bunney;Judith R. Walters;Robert H. Roth;George K. Aghajanian

  • Synaptic Dysfunction in Depression: Potential Therapeutic Targets

    Ronald S. Duman;George K. Aghajanian

  • Inhibition of both noradrenergic and serotonergic neurons in brain by the alpha-adrenergic agonist clonidine.

    T.H. Svensson;B.S. Bunney;G.K. Aghajanian

  • Serotonin Function and the Mechanism of Antidepressant Action: Reversal of Antidepressant-Induced Remission by Rapid Depletion of Plasma Tryptophan

    Pedro L. Delgado;Dennis S. Charney;Lawrence H. Price;George K. Aghajanian

  • Electrophysiological responses of serotoninergic dorsal raphe neurons to 5-HT1A and 5-HT1B agonists.

    Jeffrey S. Sprouse;George K. Aghajanian

  • Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure.

    Nanxin Li;Rong-Jian Liu;Jason M. Dwyer;Mounira Banasr

  • Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine.

    George K. Aghajanian

  • The formation of synaptic junctions in developing rat brain: A quantitative electron microscopic study

    G.K. Aghajanian;F.E. Bloom

  • Dopamine"autoreceptors": pharmacological characterization by microiontophoretic single cell recording studies.

    G. K. Aghajanian;B. S. Bunney

  • Electrophysiological and pharmacological characterization of serotonergic dorsal raphe neurons recorded extracellularly and intracellularly in rat brain slices

    C.P. Vandermaelen;G.K. Aghajanian

  • Afferent projections to the rat locus coeruleus as determined by a retrograde tracing technique.

    Jesse M. Cedarbaum;George K. Aghajanian

  • Tricyclic antidepressants: long-term treatment increases responsivity of rat forebrain neurons to serotonin

    C de Montigny;GK Aghajanian

  • Catecholamine receptors on locus coeruleus neurons: pharmacological characterization.

    Jesse M. Cedarbaum;George K. Aghajanian

  • Suppression of firing activity of 5-HT neurons in the dorsal raphe by alpha-adrenoceptor antagonists

    J.M. Baraban;G.K. Aghajanian

  • Serotonergic facilitation of facial motoneuron excitation.

    Robert B. McCall;George K. Aghajanian

  • Intracellular studies in the facial nucleus illustrating a simple new method for obtaining viable motoneurons in adult rat brain slices

    George K. Aghajanian;Kurt Rasmussen

  • Opiate withdrawal and the rat locus coeruleus: behavioral, electrophysiological, and biochemical correlates

    Kurt Rasmussen;Dana B. Beitner-Johnson;John H. Krystal;George K. Aghajanian

Frequent Co-Authors

Robert H. Roth
Robert H. Roth Yale University
Benjamin S. Bunney
Benjamin S. Bunney Yale University
Eric J. Nestler
Eric J. Nestler Icahn School of Medicine at Mount Sinai
Ronald S. Duman
Ronald S. Duman Yale University
Evelyn K. Lambe
Evelyn K. Lambe University of Toronto
Floyd E. Bloom
Floyd E. Bloom Scripps Research Institute
Michael J. Kuhar
Michael J. Kuhar Emory University
Michael A. Rogawski
Michael A. Rogawski University of California, Davis
John H. Krystal
John H. Krystal Yale University
Lawrence H. Price
Lawrence H. Price Brown University

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