D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 120 Citations 49,740 196 World Ranking 127 National Ranking 78
Medicine D-index 121 Citations 48,750 202 World Ranking 1467 National Ranking 885

Research.com Recognitions

Awards & Achievements

2000 - Member of the National Academy of Medicine (NAM)

Overview

What is he best known for?

The fields of study he is best known for:

  • Neurotransmitter
  • Dopamine
  • Internal medicine

George K. Aghajanian mainly focuses on Neuroscience, Internal medicine, Endocrinology, Serotonin and Dorsal raphe nucleus. His Neuroscience study typically links adjacent topics like Glutamate receptor. With his scientific publications, his incorporates both Endocrinology and CREB.

The study incorporates disciplines such as Tryptophan, Neurotransmitter and Therapeutic effect in addition to Serotonin. His Dorsal raphe nucleus research is multidisciplinary, incorporating elements of Raphe, Raphe nuclei, Pharmacology and Serotonergic cell groups. George K. Aghajanian interconnects Norepinephrine, Protein kinase A, Antagonist, Premovement neuronal activity and Clonidine in the investigation of issues within Locus coeruleus.

His most cited work include:

  • mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists (1753 citations)
  • DOPAMINERGIC NEURONS: EFFECT OF ANTIPSYCHOTIC DRUGS AND AMPHETAMINE ON SINGLE CELL ACTIVITY (1208 citations)
  • Molecular and Cellular Basis of Addiction (1207 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Neuroscience, Internal medicine, Endocrinology, Serotonin and Pharmacology. His studies deal with areas such as Glutamate receptor and Dorsal raphe nucleus as well as Neuroscience. His Internal medicine study frequently draws connections to other fields, such as Desipramine.

His Endocrinology study frequently draws connections between adjacent fields such as Agonist. His Serotonin study frequently draws connections to other fields, such as Postsynaptic potential. His research in Pharmacology tackles topics such as Antidepressant which are related to areas like Ketamine.

He most often published in these fields:

  • Neuroscience (42.55%)
  • Internal medicine (42.55%)
  • Endocrinology (42.20%)

What were the highlights of his more recent work (between 1995-2020)?

  • Neuroscience (42.55%)
  • Excitatory postsynaptic potential (13.83%)
  • Glutamate receptor (9.57%)

In recent papers he was focusing on the following fields of study:

His main research concerns Neuroscience, Excitatory postsynaptic potential, Glutamate receptor, Prefrontal cortex and Serotonin. He has included themes like NMDA receptor, Postsynaptic potential and Dorsal raphe nucleus in his Neuroscience study. His Dorsal raphe nucleus study combines topics in areas such as Bicuculline, Endocrinology and Raphe nuclei.

His research in Excitatory postsynaptic potential focuses on subjects like Neurotransmission, which are connected to Central nervous system. His Glutamate receptor research incorporates themes from Schizophrenia, Stimulation, Pharmacology and Neurotransmitter. His Serotonin study incorporates themes from Agonist and Hallucinogen.

Between 1995 and 2020, his most popular works were:

  • mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists (1753 citations)
  • Molecular and Cellular Basis of Addiction (1207 citations)
  • Synaptic Dysfunction in Depression: Potential Therapeutic Targets (741 citations)

In his most recent research, the most cited papers focused on:

  • Neurotransmitter
  • Dopamine
  • Internal medicine

The scientist’s investigation covers issues in Neuroscience, Excitatory postsynaptic potential, Prefrontal cortex, Serotonin and Internal medicine. The Neuroscience study combines topics in areas such as Glutamate receptor, Metabotropic glutamate receptor and Neurotransmission. George K. Aghajanian has researched Excitatory postsynaptic potential in several fields, including Apical dendrite, Bicuculline, Glutamatergic and Postsynaptic potential.

His study in Serotonin is interdisciplinary in nature, drawing from both Morning, Developmental disorder, Physiology and Tryptophan. In his research, Protein kinase A is intimately related to Endocrinology, which falls under the overarching field of Internal medicine. His research investigates the connection between Synaptogenesis and topics such as NMDA receptor that intersect with issues in Ketamine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

Nanxin Li;Boyoung Lee;Rongjian Liu;Mounira Banasr.
Science (2010)

2199 Citations

DOPAMINERGIC NEURONS: EFFECT OF ANTIPSYCHOTIC DRUGS AND AMPHETAMINE ON SINGLE CELL ACTIVITY

Benjamin S. Bunney;Judith R. Walters;Robert H. Roth;George K. Aghajanian.
Journal of Pharmacology and Experimental Therapeutics (1973)

1990 Citations

Molecular and Cellular Basis of Addiction

Eric J. Nestler;George K. Aghajanian.
Science (1997)

1817 Citations

Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine

T.H. Svensson;B.S. Bunney;G.K. Aghajanian.
Brain Research (1975)

1327 Citations

Electrophysiological responses of serotoninergic dorsal raphe neurons to 5-HT1A and 5-HT1B agonists.

Jeffrey S. Sprouse;George K. Aghajanian.
Synapse (1987)

1231 Citations

Serotonin Function and the Mechanism of Antidepressant Action: Reversal of Antidepressant-Induced Remission by Rapid Depletion of Plasma Tryptophan

Pedro L. Delgado;Dennis S. Charney;Lawrence H. Price;George K. Aghajanian.
Archives of General Psychiatry (1990)

1225 Citations

Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine.

George K. Aghajanian.
Nature (1978)

1160 Citations

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

Ronald S. Duman;George K. Aghajanian.
Science (2012)

961 Citations

The formation of synaptic junctions in developing rat brain: A quantitative electron microscopic study

G.K. Aghajanian;F.E. Bloom.
Brain Research (1967)

951 Citations

Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure.

Nanxin Li;Rong-Jian Liu;Jason M. Dwyer;Mounira Banasr.
Biological Psychiatry (2011)

916 Citations

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