2000 - Member of the National Academy of Medicine (NAM)
George K. Aghajanian mainly focuses on Neuroscience, Internal medicine, Endocrinology, Serotonin and Dorsal raphe nucleus. His Neuroscience study typically links adjacent topics like Glutamate receptor. With his scientific publications, his incorporates both Endocrinology and CREB.
The study incorporates disciplines such as Tryptophan, Neurotransmitter and Therapeutic effect in addition to Serotonin. His Dorsal raphe nucleus research is multidisciplinary, incorporating elements of Raphe, Raphe nuclei, Pharmacology and Serotonergic cell groups. George K. Aghajanian interconnects Norepinephrine, Protein kinase A, Antagonist, Premovement neuronal activity and Clonidine in the investigation of issues within Locus coeruleus.
His scientific interests lie mostly in Neuroscience, Internal medicine, Endocrinology, Serotonin and Pharmacology. His studies deal with areas such as Glutamate receptor and Dorsal raphe nucleus as well as Neuroscience. His Internal medicine study frequently draws connections to other fields, such as Desipramine.
His Endocrinology study frequently draws connections between adjacent fields such as Agonist. His Serotonin study frequently draws connections to other fields, such as Postsynaptic potential. His research in Pharmacology tackles topics such as Antidepressant which are related to areas like Ketamine.
His main research concerns Neuroscience, Excitatory postsynaptic potential, Glutamate receptor, Prefrontal cortex and Serotonin. He has included themes like NMDA receptor, Postsynaptic potential and Dorsal raphe nucleus in his Neuroscience study. His Dorsal raphe nucleus study combines topics in areas such as Bicuculline, Endocrinology and Raphe nuclei.
His research in Excitatory postsynaptic potential focuses on subjects like Neurotransmission, which are connected to Central nervous system. His Glutamate receptor research incorporates themes from Schizophrenia, Stimulation, Pharmacology and Neurotransmitter. His Serotonin study incorporates themes from Agonist and Hallucinogen.
The scientist’s investigation covers issues in Neuroscience, Excitatory postsynaptic potential, Prefrontal cortex, Serotonin and Internal medicine. The Neuroscience study combines topics in areas such as Glutamate receptor, Metabotropic glutamate receptor and Neurotransmission. George K. Aghajanian has researched Excitatory postsynaptic potential in several fields, including Apical dendrite, Bicuculline, Glutamatergic and Postsynaptic potential.
His study in Serotonin is interdisciplinary in nature, drawing from both Morning, Developmental disorder, Physiology and Tryptophan. In his research, Protein kinase A is intimately related to Endocrinology, which falls under the overarching field of Internal medicine. His research investigates the connection between Synaptogenesis and topics such as NMDA receptor that intersect with issues in Ketamine.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
Nanxin Li;Boyoung Lee;Rongjian Liu;Mounira Banasr.
Science (2010)
DOPAMINERGIC NEURONS: EFFECT OF ANTIPSYCHOTIC DRUGS AND AMPHETAMINE ON SINGLE CELL ACTIVITY
Benjamin S. Bunney;Judith R. Walters;Robert H. Roth;George K. Aghajanian.
Journal of Pharmacology and Experimental Therapeutics (1973)
Molecular and Cellular Basis of Addiction
Eric J. Nestler;George K. Aghajanian.
Science (1997)
Inhibition of both noradrenergic and serotonergic neurons in brain by the α-adrenergic agonist clonidine
T.H. Svensson;B.S. Bunney;G.K. Aghajanian.
Brain Research (1975)
Electrophysiological responses of serotoninergic dorsal raphe neurons to 5-HT1A and 5-HT1B agonists.
Jeffrey S. Sprouse;George K. Aghajanian.
Synapse (1987)
Serotonin Function and the Mechanism of Antidepressant Action: Reversal of Antidepressant-Induced Remission by Rapid Depletion of Plasma Tryptophan
Pedro L. Delgado;Dennis S. Charney;Lawrence H. Price;George K. Aghajanian.
Archives of General Psychiatry (1990)
Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine.
George K. Aghajanian.
Nature (1978)
Synaptic Dysfunction in Depression: Potential Therapeutic Targets
Ronald S. Duman;George K. Aghajanian.
Science (2012)
The formation of synaptic junctions in developing rat brain: A quantitative electron microscopic study
G.K. Aghajanian;F.E. Bloom.
Brain Research (1967)
Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure.
Nanxin Li;Rong-Jian Liu;Jason M. Dwyer;Mounira Banasr.
Biological Psychiatry (2011)
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