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George R. Heninger

George R. Heninger

D-Index & Metrics

Medicine

D-Index
108
Citations
60211
World Ranking
5896
National Ranking
3160

Overview

George R. Heninger is affiliated with Yale University in the United States. Their research spans several fields, primarily focusing on Biochemistry, Genetics and Molecular Biology, with a total of six publications in these areas. Medicine is also a significant aspect of their work, represented by three publications.

The scientist's subfields of study include Molecular Biology, Rheumatology, Genetics, Immunology, and Biological Psychiatry. This diverse range reflects a multidisciplinary approach to understanding molecular and genetic factors affecting health.

Key research topics addressed by George R. Heninger are:

  • GDF15 and Related Biomarkers
  • Extracellular vesicles in disease
  • Genetics and Neurodevelopmental Disorders
  • Macrophage Migration Inhibitory Factor
  • Circular RNAs in diseases
  • Tryptophan and brain disorders
  • Neuroinflammation and Neurodegeneration Mechanisms

Their frequent co-authors include Edward J. Goetzl, Vinod H. Srihari, Dimitrios Kapogiannis, Sinan Gülöksüz, and Maria Ferrara. Collaboration with these researchers highlights ongoing partnerships in molecular psychiatry and neuroscience.

George R. Heninger has contributed multiple research papers to journals such as The FASEB Journal, Molecular Psychiatry, and Translational Psychiatry. Notable recent publications are:

  • Abnormal levels of mitochondrial proteins in plasma neuronal extracellular vesicles in major depressive disorder, 2021, Molecular Psychiatry
  • Neural cell-derived plasma exosome protein abnormalities implicate mitochondrial impairment in first episodes of psychosis, 2021, The FASEB Journal
  • Decreased mitochondrial electron transport proteins and increased complement mediators in plasma neural-derived exosomes of early psychosis, 2020, Translational Psychiatry
  • Abnormal levels of mitochondrial Ca 2+ channel proteins in plasma neuron-derived extracellular vesicles of early schizophrenia, 2022, The FASEB Journal

Their publication records indicate a focus on mitochondrial protein abnormalities and extracellular vesicle biomarkers related to psychiatric disorders such as depression, psychosis, and schizophrenia.

Frequent publication venues include:

  • The FASEB Journal
  • Molecular Psychiatry
  • Translational Psychiatry

Best Publications

  • The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability

    Wayne K. Goodman;Lawrence H. Price;Steven A. Rasmussen;Carolyn Mazure

  • Antidepressant effects of ketamine in depressed patients

    Robert M Berman;Angela Cappiello;Amit Anand;Amit Anand;Dan A Oren;Dan A Oren

  • Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: Psychotomimetic, perceptual, cognitive, and neuroendocrine responses.

    John H. Krystal;Laurence P. Karper;John P. Seibyl;Glenna K. Freeman

  • The Yale-Brown Obsessive Compulsive Scale: II. Validity

    Wayne K. Goodman;Lawrence H. Price;Steven A. Rasmussen;Carolyn Mazure

  • A molecular and cellular theory of depression

    Ronald S. Duman;George R. Heninger;Eric J. Nestler

  • Serotonin Function and the Mechanism of Antidepressant Action: Reversal of Antidepressant-Induced Remission by Rapid Depletion of Plasma Tryptophan

    Pedro L. Delgado;Dennis S. Charney;Lawrence H. Price;George K. Aghajanian

  • Receptor sensitivity and the mechanism of action of antidepressant treatment: implications for the etiology and therapy of depression

    Dennis S. Charney;David B. Menkes;George R. Heninger

  • Abnormal Noradrenergic Function in Posttraumatic Stress Disorder

    Steven M. Southwick;John H. Krystal;C. Andrew Morgan;David Johnson

  • Haloperidol Addition in Fluvoxamine-Refractory Obsessive-Compulsive Disorder: A Double-blind, Placebo-Controlled Study in Patients With and Without Tics

    Christopher J. McDougle;Wayne K. Goodman;James F. Leckman;Nicole C. Lee

  • Noradrenergic Function in Panic Anxiety: Effects of Yohimbine in Healthy Subjects and Patients With Agoraphobia and Panic Disorder

    Dennis S. Charney;George R. Heninger;Alan Breier

  • A double-blind, placebo-controlled study of fluvoxamine in adults with autistic disorder.

    Christopher J. McDougle;Susan T. Naylor;Donald J. Cohen;Fred R. Volkmar

  • Serotonin function in anxiety. II. Effects of the serotonin agonist MCPP in panic disorder patients and healthy subjects.

    D. S. Charney;S. W. Woods;W. K. Goodman;G. R. Heninger

  • Increased anxiogenic effects of caffeine in panic disorders

    Dennis S. Charney;George R. Heninger;Peter I. Jatlow

  • Efficacy of Fluvoxamine in Obsessive-Compulsive Disorder: A Double-blind Comparison With Placebo

    Wayne K. Goodman;Lawrence H. Price;Steven A. Rasmussen;Pedro L. Delgado

  • The revised monoamine theory of depression: a modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans.

    G. R. Heninger;P. L. Delgado;D. S. Charney

  • Noradrenergic and Serotonergic Function in Posttraumatic Stress Disorder

    Steven M. Southwick;John H. Krystal;J. Douglas Bremner;C. A. Morgan

  • Major Depression in Patients With Agoraphobia and Panic Disorder

    Alan Breier;Dennis S. Charney;George R. Heninger

  • Yohimbine induced anxiety and increased noradrenergic function in humans: effects of diazepam and clonidine.

    Dennis S. Charney;George R. Heninger;D.Eugene Redmond

  • Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: implications for the role of serotonin in the mechanism of antidepressant action.

    Pedro L Delgado;Helen L Miller;Helen L Miller;Ronald M Salomon;Ronald M Salomon;Julio Licinio;Julio Licinio

  • Specificity of Serotonin Reuptake Inhibitors in the Treatment of Obsessive-Compulsive Disorder: Comparison of Fluvoxamine and Desipramine

    Wayne K. Goodman;Lawrence H. Price;Pedro L. Delgado;Joseph Palumbo

Frequent Co-Authors

Dennis S. Charney
Dennis S. Charney Icahn School of Medicine at Mount Sinai
Lawrence H. Price
Lawrence H. Price Brown University
John H. Krystal
John H. Krystal Yale University
Scott W. Woods
Scott W. Woods Yale University
Wayne K. Goodman
Wayne K. Goodman Baylor College of Medicine
Christopher J. McDougle
Christopher J. McDougle Harvard University
Robert T. Malison
Robert T. Malison Yale University
James F. Leckman
James F. Leckman Yale University
John Seibyl
John Seibyl Yale University
Andrew Goddard
Andrew Goddard University of California, San Francisco

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