World's Best Scientists 2026 revealed!
Nicholas J. Skelton

Nicholas J. Skelton

D-Index & Metrics

Chemistry

D-Index
49
Citations
10013
World Ranking
14716
National Ranking
3760

Nicholas J. Skelton publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Nicholas J. Skelton sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 144 publications — 12th percentile

12% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Nicholas J. Skelton D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Nicholas J. Skelton sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 49 D-Index — 19th percentile

19% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Nicholas J. Skelton is affiliated with Genentech in the United States. Their research spans key areas in biochemistry, genetics, molecular biology, and medicine, with a focus on both fundamental and applied aspects of these fields.

Skelton's scholarly work extensively covers several subfields, including:

  • Molecular Biology
  • Computational Theory and Mathematics
  • Cancer Research
  • Surgery
  • Molecular Medicine

The scientist's main topics of investigation include computational drug discovery methods, lipoproteins and cardiovascular health, vaccines and immunoinformatics approaches, antibiotic resistance in bacteria, bacterial genetics and biotechnology, lipid membrane structure and behavior, and genetics, bioinformatics, and biomedical research.

Some of the frequent publication venues where Skelton's work appears are:

  • Nature Communications
  • ACS Chemical Biology
  • Nature Biotechnology
  • Nature
  • Biochemistry

Prominent co-authors in their research collaborations include Elizabeth Skippington, Steven T. Rutherford, Man-Wah Tan, Kerry R. Buchholz, and Anh Miu. These collaborators have contributed to multiple joint publications.

Representative recent papers authored or co-authored by Skelton include:

  • Structure of the essential inner membrane lipopolysaccharide-PbgA complex, 2020, Nature
  • Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine, 2020, ACS Chemical Biology
  • A Multifaceted Hit-Finding Approach Reveals Novel LC3 Family Ligands, 2022, Biochemistry
  • Design of Organo-Peptides As Bipartite PCSK9 Antagonists, 2020, ACS Chemical Biology
  • A data science roadmap for open science organizations engaged in early-stage drug discovery, 2024, Nature Communications

Best Publications

  • Tryptophan zippers: Stable, monomeric β-hairpins

    Andrea G. Cochran;Nicholas J. Skelton;Melissa A. Starovasnik

  • Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

    Till Maurer;Lindsay S. Garrenton;Angela Oh;Keith Pitts

  • Protein NMR Spectroscopy: principles and practice, 2nd ed.

    John Cavanagh;WJ Fairbrother;AG Palmer;M Rance

  • Suppression of the effects of cross-correlation between dipolar and anisotropic chemical shift relaxation mechanisms in the measurement of spin-spin relaxation rates

    Arthur G. Palmer;Nicholas J. Skelton;Walter J. Chazin;Peter E. Wright

  • Peptide exosite inhibitors of factor VIIa as anticoagulants

    Mark S. Dennis;Charles Eigenbrot;Nicholas J. Skelton;Mark H. Ultsch

  • A General Method for Constraining Short Peptides to an α-Helical Conformation

    J. Christopher Phelan;Nicholas J. Skelton;and Andrew C. Braisted;Robert S. McDowell

  • Backbone dynamics of calcium-loaded calbindin D9k studied by two-dimensional proton-detected 15N NMR spectroscopy.

    J Kördel;N J Skelton;M Akke;A G Palmer rd

  • Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding.

    Sarah G. Hymowitz;Darshana R. Patel;Heidi J.A. Wallweber;Steven Runyon

  • Origins of PDZ Domain Ligand Specificity STRUCTURE DETERMINATION AND MUTAGENESIS OF THE ERBIN PDZ DOMAIN

    Nicholas J. Skelton;Michael F.T. Koehler;Kerry Zobel;Wai Lee Wong

  • Structure of a CXC chemokine-receptor fragment in complex with interleukin-8.

    Nicholas J Skelton;Cliff Quan;Dorothea Reilly;Henry Lowman

  • Effects of ion binding on the backbone dynamics of calbindin D9k determined by 15N NMR relaxation

    Mikael Akke;Nicholas J. Skelton;Johan Kordel;Arthur G. Palmer

  • Practical Aspects of Two-Dimensional Proton-Detected 15N Spin Relaxation Measurements

    N.J. Skelton;A.G. Palmer;M. Akke;J. Kordel

  • An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt

    Kui Lin;Jie Lin;Wen-I Wu;Joshua Ballard

  • Distinct but overlapping epitopes for the interaction of a CC-chemokine with CCR1, CCR3 and CCR5.

    Deepika R. Pakianathan;Ellen G. Kuta;Dean R. Artis;Nicholas J. Skelton

  • Determination of the solution structure of apo calbindin D9k by NMR spectroscopy

    Nicholas J. Skelton;Johan Kördel;Walter J. Chazin

  • Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor

    Yingnan Zhang;Charles Eigenbrot;Lijuan Zhou;Steven Shia

  • Proton NMR assignments and solution conformation of RANTES, a chemokine of the C-C type.

    Nicholas J. Skelton;Fernando Aspiras;John Ogez;Thomas J. Schall

  • Signal transduction versus buffering activity in Ca(2+)-binding proteins.

    Nicholas J. Skelton;Johan Kördel;Mikael Akke;Sture Forsén

  • A Minimal Peptide Scaffold for β-Turn Display: Optimizing a Strand Position in Disulfide-Cyclized β-Hairpins

    Andrea G. Cochran;Ricky T. Tong;Melissa A. Starovasnik;Eleanor J. Park

  • Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumors.

    James F. Blake;Rui Xu;Josef R. Bencsik;Dengming Xiao

Frequent Co-Authors

Dudley H. Williams
Dudley H. Williams University of Cambridge
Mark Rance
Mark Rance University of Cincinnati
Sachdev S. Sidhu
Sachdev S. Sidhu University of Waterloo
Walter J. Chazin
Walter J. Chazin Vanderbilt University
Mark Ultsch
Mark Ultsch Genentech
Mikael Akke
Mikael Akke Lund University
Christian Wiesmann
Christian Wiesmann Novartis (Switzerland)

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