What is he best known for?
The fields of study he is best known for:
Henry B. Lowman mainly investigates Biochemistry, Molecular biology, Phage display, Antibody and Receptor.
His work on Gene and Phagemid as part of his general Biochemistry study is frequently connected to Conjugate, Conjugated system and Cysteine, thereby bridging the divide between different branches of science.
His Molecular biology research incorporates elements of Humanized antibody, VEGF receptors, Affinity maturation and Tumor growth.
Henry B. Lowman combines subjects such as Mutagenesis, Combinatorial chemistry and Stereochemistry with his study of Phage display.
His Antibody research integrates issues from In vivo, Antigen and Virology.
His Receptor research is multidisciplinary, relying on both Affinities and Pharmacokinetics.
His most cited work include:
- Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen. (1159 citations)
- Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index (916 citations)
- Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants (760 citations)
What are the main themes of his work throughout his whole career to date?
Henry B. Lowman spends much of his time researching Antibody, Biochemistry, Molecular biology, Phage display and Internal medicine.
His Antibody research is multidisciplinary, incorporating elements of Amino acid, Antigen and Virology.
His work on Peptide and Receptor as part of general Biochemistry study is frequently connected to Isomerization and Conjugate, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His research in Molecular biology intersects with topics in Plasma protein binding, Phagemid and Humanized antibody.
His biological study spans a wide range of topics, including Bacteriophage, Mutant and Affinity maturation.
His work in Internal medicine addresses subjects such as Endocrinology, which are connected to disciplines such as Insulin-like growth factor.
He most often published in these fields:
- Antibody (39.39%)
- Biochemistry (31.17%)
- Molecular biology (17.75%)
What were the highlights of his more recent work (between 2007-2020)?
- Antibody (39.39%)
- Monoclonal antibody (9.52%)
- Molecular biology (17.75%)
In recent papers he was focusing on the following fields of study:
Antibody, Monoclonal antibody, Molecular biology, Amino acid and Biochemistry are his primary areas of study.
The study incorporates disciplines such as Nucleic acid and Virology in addition to Antibody.
His studies deal with areas such as Omalizumab, Pharmacokinetics, Death domain and In vivo as well as Monoclonal antibody.
His Molecular biology study combines topics in areas such as Plasma protein binding, CD20, Humanized antibody, Receptor and Cross reactive antibodies.
His Phage display and Affinity maturation study in the realm of Biochemistry interacts with subjects such as Cysteine and Isomerization.
His studies in Phage display integrate themes in fields like Stereochemistry, Fusion protein and Antigen.
Between 2007 and 2020, his most popular works were:
- Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index (916 citations)
- Engineering human IgG1 affinity to human neonatal Fc receptor: impact of affinity improvement on pharmacokinetics in primates. (271 citations)
- Interaction between bevacizumab and murine VEGF-A: a reassessment. (194 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Antibody, Monoclonal antibody, Virology, Pharmacokinetics and Pharmacology.
His work carried out in the field of Antibody brings together such families of science as Amino acid, Biochemistry, Molecular biology and Antigen.
His work on Phage display and Glycosylation as part of general Biochemistry research is often related to Cysteine, thus linking different fields of science.
The concepts of his Phage display study are interwoven with issues in Alanine, Biotinylation and Stereochemistry.
His research investigates the connection between Pharmacokinetics and topics such as Neonatal Fc receptor that intersect with problems in Wild type and Internal medicine.
His work is dedicated to discovering how Pharmacology, In vivo are connected with Potency, Immunoglobulin G and Vascular endothelial growth factor A and other disciplines.
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