D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 77 Citations 22,924 156 World Ranking 2966 National Ranking 1560

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

The scientist’s investigation covers issues in Molecular biology, Fucosyltransferase, Selectin, Immunology and Biochemistry. His Molecular biology research incorporates themes from Complementary DNA, Molecular cloning, Protein primary structure and Peptide sequence. His study explores the link between Fucosyltransferase and topics such as Sialyl-Lewis X that cross with problems in Cell adhesion.

His Selectin research is multidisciplinary, incorporating elements of Leukocyte Trafficking, Lymphocyte homing receptor, Leukocyte Rolling and Effector. His Immunology research integrates issues from Cell migration and Cell biology. His work on Glycan and Fucose is typically connected to Nucleotide salvage as part of general Biochemistry study, connecting several disciplines of science.

His most cited work include:

  • ELAM-1--dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA. (690 citations)
  • The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis (651 citations)
  • Fucose: biosynthesis and biological function in mammals. (642 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Molecular biology, Biochemistry, Fucosyltransferase, Immunology and Antibody. His Molecular biology study combines topics in areas such as Complementary DNA, Molecular cloning, Gene and Epitope. His studies deal with areas such as Southern blot and Nucleic acid sequence as well as Molecular cloning.

His Biochemistry research is multidisciplinary, relying on both Stereochemistry and Antigen. His work investigates the relationship between Fucosyltransferase and topics such as Sialyl-Lewis X that intersect with problems in Glycosylation and High endothelial venules. Immunology is frequently linked to Cell biology in his study.

He most often published in these fields:

  • Molecular biology (42.86%)
  • Biochemistry (31.53%)
  • Fucosyltransferase (31.03%)

What were the highlights of his more recent work (between 2009-2020)?

  • Antibody (18.23%)
  • Immunology (26.60%)
  • Cell biology (17.73%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Antibody, Immunology, Cell biology, Molecular biology and Monoclonal antibody. His study in Antibody is interdisciplinary in nature, drawing from both Biochemistry, Virology, Chinese hamster ovary cell and Recombinant DNA. His research in Immunology intersects with topics in Heparan sulfate and Perlecan.

John B. Lowe interconnects Lymphatic system and Lymphocyte in the investigation of issues within Cell biology. He integrates Molecular biology with P-selectin glycoprotein ligand-1 in his research. His work deals with themes such as Chromatography and Pharmacology, which intersect with Monoclonal antibody.

Between 2009 and 2020, his most popular works were:

  • Multiplexed ion beam imaging of human breast tumors (477 citations)
  • Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung. (117 citations)
  • Endothelial Heparan Sulfate Controls Chemokine Presentation in Recruitment of Lymphocytes and Dendritic Cells to Lymph Nodes (114 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Antibody, Cell biology, Immunology, Internal medicine and Pharmacokinetics are his primary areas of study. The various areas that John B. Lowe examines in his Antibody study include In vitro and Pharmacology. In the subject of general Immunology, his work in Immune system, Chemokine and Lymphocyte homing receptor is often linked to Cell fate determination, thereby combining diverse domains of study.

His work in Internal medicine tackles topics such as Endocrinology which are related to areas like Amino acid and PI3K/AKT/mTOR pathway. John B. Lowe has included themes like Cancer, Angiogenesis, Neuropilin 1 and Pharmacology toxicology in his Pharmacokinetics study. The Immunogenicity study combines topics in areas such as Molecular biology, Bioassay and Biochemistry.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

ELAM-1--dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA.

John B. Lowe;Lloyd M. Stoolman;Rajan P. Nair;Robert D. Larsen.
Cell (1990)

956 Citations

Fucose: biosynthesis and biological function in mammals.

Daniel J. Becker;John B. Lowe.
Glycobiology (2003)

891 Citations

Role of Glycosylation in Development

Robert S Haltiwanger;John B Lowe.
Annual Review of Biochemistry (2003)

863 Citations

The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis

Petr Malý;Aron D Thall;Bronislawa Petryniak;Clare E Rogers.
Cell (1996)

850 Citations

A Genetic Approach to Mammalian Glycan Function

John B. Lowe;Jamey D. Marth.
Annual Review of Biochemistry (2003)

702 Citations

Sequence and Expression of a Candidate for the Human Secretor Blood Group α(1,2)Fucosyltransferase Gene (FUT2) HOMOZYGOSITY FOR AN ENZYME-INACTIVATING NONSENSE MUTATION COMMONLY CORRELATES WITH THE NON-SECRETOR PHENOTYPE

Robert J. Kelly;Sylvie Rouquier;Dominique Giorgi;Gregory G. Lennon.
Journal of Biological Chemistry (1995)

686 Citations

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense.

Andrew W. Roberts;Chaekyun Kim;Ling Zhen;John B. Lowe.
Immunity (1999)

634 Citations

A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group alpha(1,3/1,4)fucosyltransferase.

Jolanta F. Kukowska-Latallo;Robert D. Larsen;Rajan P. Nair;John B. Lowe.
Genes & Development (1990)

620 Citations

Multiplexed ion beam imaging of human breast tumors

Michael Angelo;Sean C Bendall;Rachel Finck;Matthew B Hale.
Nature Medicine (2014)

556 Citations

A role for leukocyte-endothelial adhesion mechanisms in epilepsy

Paolo F Fabene;Graciela Navarro Mora;Marianna Martinello;Barbara Rossi.
Nature Medicine (2008)

497 Citations

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