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Biology and Biochemistry
USA
2026
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Chemistry
USA
2026

D-Index & Metrics

Chemistry

D-Index
159
Citations
89541
World Ranking
98
National Ranking
52

Biology and Biochemistry

D-Index
162
Citations
92620
World Ranking
114
National Ranking
87

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United States Leader Award
  • 2026 - Research.com Chemistry in United States Leader Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2025 - Research.com Chemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2021 - Welch Award in Chemistry, Robert A. Welch Foundation
  • 2014 - Fellow, National Academy of Inventors
  • 2014 - Wolf Prize in Chemistry, Wolf Foundation for his numerous and original contributions to the development of innovative methods for the programmable and applied synthesis of complex oligosaccharides and glycol-proteins.
  • 2012 - Arthur C. Cope Award, American Chemical Society (ACS)
  • 2008 - F.A. Cotton Medal for Excellence in Chemical Research, American Chemical Society (ACS)
  • 2007 - Fellow, The World Academy of Sciences
  • 2004 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2002 - Member of the National Academy of Sciences
  • 1996 - Fellow of the American Academy of Arts and Sciences

Overview

Chi-Huey Wong is affiliated with the Scripps Research Institute in the United States. Their research spans multiple disciplines, primarily within Biochemistry, Genetics and Molecular Biology, and Chemistry. The scientist has published extensively, with a significant focus on Molecular Biology, Organic Chemistry, Immunology, Biochemistry, and Spectroscopy.

Key topics in their research include Glycosylation and Glycoproteins Research, Carbohydrate Chemistry and Synthesis, Amino Acid Enzymes and Metabolism, Enzyme Catalysis and Immobilization, Immunotherapy and Immune Responses, Advanced Biosensing and Bioanalysis Techniques, and Influenza Virus Research Studies.

Recent significant publications include:

  • Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection, 2021, Proceedings of the National Academy of Sciences
  • Glycoconjugates: Synthesis, Functional Studies, and Therapeutic Developments, 2022, Chemical Reviews
  • Vaccination with SARS-CoV-2 spike protein lacking glycan shields elicits enhanced protective responses in animal models, 2022, Science Translational Medicine
  • A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2, 2020, Cell Reports
  • Automated Quantification of Hydroxyl Reactivities: Prediction of Glycosylation Reactions, 2021, Angewandte Chemie International Edition

Frequent co-authors collaborating with this scientist include Ting-Jen Rachel Cheng, Tsui-Ling Hsu, Che Ma, Szu-Wen Wang, and Kuo-I Lin.

Their work has appeared repeatedly in several key publication venues, including Catalysis from A to Z, Journal of the American Chemical Society, ACS Chemical Biology, bioRxiv (Cold Spring Harbor Laboratory), and The Journal of Organic Chemistry.

Throughout their career, Chi-Huey Wong has been recognized with several awards and honors. These include:

  • Welch Award in Chemistry, Robert A. Welch Foundation, 2021
  • Fellow, National Academy of Inventors, 2014
  • Wolf Prize in Chemistry, Wolf Foundation, 2014, awarded for numerous and original contributions to innovative methods in programmable synthesis of complex oligosaccharides and glycoproteins
  • Arthur C. Cope Award, American Chemical Society, 2012
  • F.A. Cotton Medal for Excellence in Chemical Research, American Chemical Society, 2008
  • Fellow, The World Academy of Sciences, 2007
  • Fellow of the American Association for the Advancement of Science, 2004
  • Member of the National Academy of Sciences, 2002
  • Fellow of the American Academy of Arts and Sciences, 1996

Best Publications

  • Broad neutralization coverage of HIV by multiple highly potent antibodies

    Laura M. Walker;Michael Huber;Michael Huber;Katie J. Doores;Katie J. Doores;Emilia Falkowska;Emilia Falkowska

  • Enzymes in synthetic organic chemistry

    Chi-Huey Wong;G. M. Whitesides

  • Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

    Ola Blixt;Steve Head;Tony Mondala;Christopher Scanlan

  • Enzymes for chemical synthesis

    Kathryn M. Koeller;Chi-Huey Wong

  • Recognition of bacterial glycosphingolipids by natural killer T cells

    Yuki Kinjo;Douglass Wu;Gisen Kim;Guo-Wen Xing

  • The Catalytic Asymmetric Aldol Reaction.

    Timothy D. Machajewski;Chi-Huey Wong

  • Programmable one-pot oligosaccharide synthesis

    Chi-Huey Wong;Zhiyuan Zhang;Ian Ollmann;Timor Baasov

  • A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

    Robert Pejchal;Katie J. Doores;Katie J. Doores;Laura M. Walker;Reza Khayat

  • Lipase-catalyzed irreversible transesterifications using enol esters as acylating reagents: preparative enantio- and regioselective syntheses of alcohols, glycerol derivatives, sugars, and organometallics

    Yi Fong. Wang;James J. Lalonde;Milagros. Momongan;David E. Bergbreiter

  • Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria.

    Yuki Kinjo;Emmanuel Tupin;Douglass Wu;Masakazu Fujio

  • Carbohydrate Mimetics: A New Strategy for Tackling the Problem of Carbohydrate‐Mediated Biological Recognition

    Pamela Sears;Chi-Huey Wong

  • Identification of an IL-17–producing NK1.1neg iNKT cell population involved in airway neutrophilia

    Marie-Laure Michel;Alexandre Castro Keller;Christophe Paget;Christophe Paget;Masakazu Fujio

  • Selectfluor: mechanistic insight and applications.

    Paul T. Nyffeler;Sergio Gonzalez Durón;Michael D. Burkart;Stéphane P. Vincent

  • Synthesis of sugar arrays in microtiter plate.

    Fabio Fazio;Marian C. Bryan;Ola Blixt;James C. Paulson

  • Toward automated synthesis of oligosaccharides and glycoproteins.

    Pamela Sears;Chi-Huey Wong

  • Chemical chaperones increase the cellular activity of N370S β-glucosidase: A therapeutic strategy for Gaucher disease

    Anu R. Sawkar;Wei-Chieh Cheng;Ernest Beutler;Chi-Huey Wong

  • HIV-1 protease: mechanism and drug discovery

    Ashraf Brik;Chi-Huey Wong

  • A Potent and Highly Selective Inhibitor of Human α-1,3-Fucosyltransferase via Click Chemistry

    Lac V Lee;Michael L Mitchell;Shih-Jung Huang;Valery V Fokin

  • Selectinminus signCarbohydrate Interactions: From Natural Ligands to Designed Mimics.

    Eric E. Simanek;Glenn J. McGarvey;Jill A. Jablonowski;Chi-Huey Wong

  • Synthesis of complex carbohydrates and glycoconjugates: enzyme-based and programmable one-pot strategies.

    Kathryn M. Koeller;Chi-Huey Wong

  • Small molecules targeting severe acute respiratory syndrome human coronavirus

    Chung Yi Wu;Jia Tsrong Jan;Shiou Hwa Ma;Chin Jung Kuo

Frequent Co-Authors

Chung-Yi Wu
Chung-Yi Wu Academia Sinica
Jim-Min Fang
Jim-Min Fang National Taiwan University
Alice L. Yu
Alice L. Yu University of California, San Diego
Ashraf Brik
Ashraf Brik Technion – Israel Institute of Technology
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Chun-Cheng Lin
Chun-Cheng Lin National Tsing Hua University
Shuichi Takayama
Shuichi Takayama Georgia Institute of Technology
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
George M. Whitesides
George M. Whitesides Harvard University
John H. Elder
John H. Elder Scripps Research Institute

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