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Immunology

D-Index
65
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18641
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2815
National Ranking
12

Overview

Penny L. Moore is affiliated with the National Health Laboratory Service in South Africa. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a focus on Infectious Diseases, Virology, Molecular Biology, Immunology, and Radiology, Nuclear Medicine and Imaging.

The scientist's work covers several main topics, including:

  • SARS-CoV-2 and COVID-19 Research
  • HIV Research and Treatment
  • COVID-19 Clinical Research Studies
  • Monoclonal and Polyclonal Antibodies Research
  • Vaccines and Immunoinformatics Approaches
  • Vaccine Coverage and Hesitancy
  • Immune Cell Function and Interaction

They have contributed to a number of recent papers, notable among them are:

  • "Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant", 2021, New England Journal of Medicine
  • "SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma", 2021, Nature Medicine
  • "Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization", 2021, Nature
  • "T cell responses to SARS-CoV-2 spike cross-recognize Omicron", 2022, Nature
  • "SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection", 2021, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors who have collaborated extensively with Penny L. Moore include:

  • Thandeka Moyo-Gwete
  • Simone I. Richardson
  • Tandile Hermanus
  • Prudence Kgagudi
  • Nelia P. Manamela

The scientist's publications have frequently appeared in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Virology
  • Frontiers in Immunology
  • Cell Host & Microbe
  • PLoS Pathogens

Best Publications

  • Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization

    Unknown

  • SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma.

    Constantinos Kurt Wibmer;Frances Ayres;Tandile Hermanus;Mashudu Madzivhandila

  • Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant.

    S. A. Madhi;V. Baillie;C. L. Cutland;M. Voysey

  • Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.

    Nicole A. Doria-Rose;Chaim A. Schramm;Jason Gorman;Penny L. Moore

  • T cell responses to SARS-CoV-2 spike cross-recognize Omicron

    Unknown

  • The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4+ T Cell Decline and High Viral Load during Acute Infection

    Elin S. Gray;Maphuti C. Madiga;Tandile. Hermanus;Penny L. Moore

  • SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection

    Unknown

  • Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes

    Constantinos Kurt Wibmer;Jinal N Bhiman;Elin S Gray;Nancy Tumba

  • Nature of nonfunctional envelope proteins on the surface of human immunodeficiency virus type 1.

    Penny L. Moore;Emma T. Crooks;Lauren Porter;Ping Zhu

  • Neutralizing Antibody Responses in Acute Human Immunodeficiency Virus Type 1 Subtype C Infection

    E. S. Gray;P. L. Moore;I. A. Choge;J. M. Decker

  • Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

    Penny L. Moore;Elin S. Gray;C. Kurt Wibmer;C. Kurt Wibmer;Jinal N. Bhiman;Jinal N. Bhiman

  • SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape

    Unknown

  • The Impact of Evolving SARS-CoV-2 Mutations and Variants on COVID-19 Vaccines

    Unknown

  • Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection.

    Penny L. Moore;Nthabeleng Ranchobe;Bronwen E. Lambson;Elin S. Gray

  • New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

    Nicole A. Doria-Rose;Jinal N. Bhiman;Jinal N. Bhiman;Ryan S. Roark;Chaim A. Schramm

  • Limited neutralizing antibody specificities drive neutralization escape in early HIV-1 subtype C infection

    Penny L Moore;Nthabeleng Ranchobe;Bronwen E Lambson;Elin S Gray

  • Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals

    Georgia D. Tomaras;James M. Binley;Elin S. Gray;Emma T. Crooks

  • Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

    Jinal N. Bhiman;Jinal N. Bhiman;Colin. Anthony;Nicole A. Doria-Rose;Owen. Karimanzira

  • Antibody Specificities Associated with Neutralization Breadth in Plasma from Human Immunodeficiency Virus Type 1 Subtype C-Infected Blood Donors

    Elin S. Gray;Natasha Taylor;Diane Wycuff;Penny L. Moore

  • Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

    Jason Gorman;Cinque Soto;Max M Yang;Thaddeus M Davenport

  • Potent and Broad Neutralization of HIV-1 Subtype C by Plasma Antibodies Targeting a Quaternary Epitope Including Residues in the V2 Loop

    Penny L. Moore;Elin S. Gray;Daniel Sheward;Maphuti C. Madiga

  • The C3-V4 Region Is a Major Target of Autologous Neutralizing Antibodies in Human Immunodeficiency Virus Type 1 Subtype C Infection

    Penelope L. Moore;Elin Solomonovna. Gray;Isaac Ang'Ang'A. Choge;Nthabeleng. Ranchobe

  • Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.

    Lingshu Wang;Tongqing Zhou;Yi Zhang;Eun Sung Yang

  • Features of recently transmitted HIV-1 clade C viruses that impact antibody recognition: implications for active and passive immunization

    Cecilia Rademeyer;Bette Korber;Michael S Seaman;Elena E Giorgi

  • A comparative immunogenicity study of HIV-1 virus-like particles bearing various forms of envelope proteins, particles bearing no envelope and soluble monomeric gp120.

    Emma T. Crooks;Penny L. Moore;Michael Franti;Charmagne S. Cayanan

Frequent Co-Authors

Lynn Morris
Lynn Morris University of the Witwatersrand
Carolyn Williamson
Carolyn Williamson University of Cape Town
Salim S. Abdool Karim
Salim S. Abdool Karim Centre for the AIDS Programme of Research in South Africa
Jinal N. Bhiman
Jinal N. Bhiman University of the Witwatersrand
Elin S. Gray
Elin S. Gray Edith Cowan University
John R. Mascola
John R. Mascola ModeX Therapeutics
Philip J. R. Goulder
Philip J. R. Goulder University of Oxford
Lawrence Shapiro
Lawrence Shapiro Columbia University
Koleka Mlisana
Koleka Mlisana National Health Laboratory Service
Nicole A. Doria-Rose
Nicole A. Doria-Rose National Institute of Allergy and Infectious Diseases

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