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Chemistry

D-Index
71
Citations
15370
World Ranking
5662
National Ranking
419

Overview

Klaus Gerwert is affiliated with Ruhr University Bochum in Germany. Their research spans multiple areas within medicine and biochemistry, genetics, and molecular biology.

Their main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of particular focus are:

  • Molecular Biology
  • Biophysics
  • Physiology
  • Neurology
  • Radiology, Nuclear Medicine and Imaging

Klaus Gerwert's research topics cover:

  • Alzheimer's disease research and treatments
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Dementia and Cognitive Impairment Research
  • Spectroscopy and Chemometric Analyses
  • AI in cancer detection
  • Parkinson's Disease Mechanisms and Treatments
  • Photoreceptor and optogenetics research

Frequent publication venues for their work include:

  • Alzheimer s & Dementia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer s Research & Therapy
  • Analytical Chemistry
  • Biophysical Journal

Selected recent papers authored by Klaus Gerwert or with significant contribution include:

  • The subcellular arrangement of alpha-synuclein proteoforms in the Parkinson's disease brain as revealed by multicolor STED microscopy (2021, Acta Neuropathologica)
  • Association of plasma biomarkers, p-tau181, glial fibrillary acidic protein, and neurofilament light, with intermediate and long-term clinical Alzheimer's disease risk: Results from a prospective cohort followed over 17 years (2022, Alzheimer s & Dementia)
  • Association of Kidney Function With Development of Alzheimer Disease and Other Dementias and Dementia-Related Blood Biomarkers (2023, JAMA Network Open)
  • Comparability of Raman Spectroscopic Configurations: A Large Scale Cross-Laboratory Study (2020, Analytical Chemistry)
  • Label-free vibrational imaging of different Aβ plaque types in Alzheimer's disease reveals sequential events in plaque development (2020, Acta Neuropathologica Communications)

Klaus Gerwert frequently co-authors with several scientists, including:

  • Léon Beyer
  • Axel Mosig
  • Frederik Großerueschkamp
  • Hannah Stocker
  • Hermann Brenner

Best Publications

  • Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes.

    Sarah H Shahmoradian;Sarah H Shahmoradian;Amanda J Lewis;Christel Genoud;Jürgen Hench

  • Electrostatic calculations of the pKa values of ionizable groups in bacteriorhodopsin

    Donald Bashford;Klaus Gerwert

  • Functional waters in intraprotein proton transfer monitored by FTIR difference spectroscopy

    Florian Garczarek;Klaus Gerwert

  • Role of aspartate-96 in proton translocation by bacteriorhodopsin.

    Klaus Gerwert;Benno Hess;Jorg Soppa;Dieter Oesterhelt

  • Light-driven protonation changes of internal aspartic acids of bacteriorhodopsin: an investigation of static and time-resolved infrared difference spectroscopy using [4-13C]aspartic acid labeled purple membrane

    Engelhard M;Gerwert K;Hess B;Kreutz W

  • Simultaneous monitoring of light-induced changes in protein side-group protonation, chromophore isomerization, and backbone motion of bacteriorhodopsin by time-resolved Fourier-transform infrared spectroscopy

    Klaus Gerwert;Georg Souvignier;Benno Hess

  • Bacteriorhodopsin's Intramolecular Proton-Release Pathway Consists of a Hydrogen-Bonded Network†

    Robin Rammelsberg;Gregor Huhn;Mathias Lübben;Klaus Gerwert

  • Proton binding within a membrane protein by a protonated water cluster

    Florian Garczarek;Leonid S. Brown;Janos K. Lanyi;Klaus Gerwert

  • Electrostatic calculations of the pKa values of ionizable groups in bacteriorhodopsin.

    Unknown

  • Evidence for light-induced 13-cis, 14-s-cis isomerization in bacteriorhodopsin obtained by FTIR difference spectroscopy using isotopically labelled retinals.

    Klaus Gerwert;Friedrich Siebert

  • Proton transfer via a transient linear water-molecule chain in a membrane protein.

    Erik Freier;Steffen Wolf;Klaus Gerwert

  • Structure of the I1 early intermediate of photoactive yellow protein by FTIR spectroscopy.

    Ronald Brudler;Robin Rammelsberg;Tammy T. Woo;Elizabeth D. Getzoff

  • A model-independent approach to assigning bacteriorhodopsin's intramolecular reactions to photocycle intermediates

    B. Hessling;G. Souvignier;K. Gerwert

  • IR Spectra of Phosphate Ions in Aqueous Solution: Predictions of a DFT/MM Approach Compared with Observations

    Marco Klähn;Gerald Mathias;Carsten Kötting;Marco Nonella

  • Amyloid blood biomarker detects Alzheimer's disease

    Andreas Nabers;Laura Perna;Julia Lange;Ute Mons

  • Proteins in action monitored by time-resolved FTIR spectroscopy.

    Carsten Kötting;Klaus Gerwert

  • Asymmetric binding of the 1- and 4-C=O groups of QA in Rhodobacter sphaeroides R26 reaction centres monitored by Fourier transform infra-red spectroscopy using site-specific isotopically labelled ubiquinone-10.

    R. Brudler;H. J. M. De Groot;W. B. S. Van Liemt;W. F. Steggerda

  • Coupling of light-induced electron transfer to proton uptake in photosynthesis

    André Remy;Klaus Gerwert

  • Monitoring the GAP catalyzed H-Ras GTPase reaction at atomic resolution in real time.

    Christoph Allin;Mohammad Reza Ahmadian;Alfred Wittinghofer;Klaus Gerwert

  • N-Ras forms dimers at POPC membranes.

    Jörn Güldenhaupt;Till Rudack;Peter Bachler;Daniel Mann

  • Label-free imaging of drug distribution and metabolism in colon cancer cells by Raman microscopy

    Samir F El-Mashtoly;Dennis Petersen;Hesham K Yosef;Axel Mosig

Frequent Co-Authors

Benno Hess
Benno Hess Max Planck Society
Peter Hegemann
Peter Hegemann Humboldt-Universität zu Berlin
Dieter Oesterhelt
Dieter Oesterhelt Max Planck Society
Thomas Brüning
Thomas Brüning Ruhr University Bochum
Hermann Brenner
Hermann Brenner German Cancer Research Center
Jens Wiltfang
Jens Wiltfang University of Göttingen
Max Diem
Max Diem Northeastern University
Alfred Wittinghofer
Alfred Wittinghofer Max Planck Society
Roger S. Goody
Roger S. Goody Max Planck Society
Ben Schöttker
Ben Schöttker Heidelberg University

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