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Medicine

D-Index
81
Citations
29784
World Ranking
16471
National Ranking
858

Overview

Thomas Brüning is affiliated with Ruhr University Bochum in Germany. Their research spans primary fields of Medicine and Environmental Science, with a focus on several subfields including Health, Toxicology and Mutagenesis; Pulmonary and Respiratory Medicine; Genetics; Public Health, Environmental and Occupational Health; and Cancer Research.

The main topics of Thomas Brüning's work cover diverse areas such as:

  • Air Quality and Health Impacts
  • Occupational and environmental lung diseases
  • Occupational exposure and asthma
  • Effects and risks of endocrine disrupting chemicals
  • Carcinogens and Genotoxicity Assessment
  • BRCA gene mutations in cancer
  • Genetic Associations and Epidemiology

The scientist has contributed to several frequent publication venues, indicating a broad influence across toxicology, occupational health, and environmental research. Prominent venues include:

  • Archives of Toxicology
  • ASU Arbeitsmedizin Sozialmedizin Umweltmedizin
  • International Journal of Hygiene and Environmental Health
  • Environment International
  • International Archives of Occupational and Environmental Health

Thomas Brüning's recent publications highlight significant contributions to genetics and cancer research, particularly related to breast cancer susceptibility and risk analysis. Notable papers include:

  • "Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women" (2021, New England Journal of Medicine)
  • "Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses" (2020, Nature Genetics)
  • "Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes" (2020, Nature Genetics)
  • "Pathology of Tumors Associated With Pathogenic Germline Variants in 9 Breast Cancer Susceptibility Genes" (2022, JAMA Oncology)
  • "Phthalate metabolites in urine of children and adolescents in Germany. Human biomonitoring results of the German Environmental Survey GerES V, 2014-2017" (2020, International Journal of Hygiene and Environmental Health)

The scientist collaborates frequently with peers in related research areas. Regular coauthors include:

  • Thomas Behrens
  • Holger M. Koch
  • Dirk Taeger
  • Heiko U. Käfferlein
  • Jürgen Bünger

Best Publications

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • RAD51B in Familial Breast Cancer

    Liisa M. Pelttari;Sofia Khan;Mikko Vuorela;Johanna I. Kiiski

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

    Xiaohong R. Yang;Jenny Chang-Claude;Ellen L. Goode;Fergus J. Couch

  • Assessing exposure to phthalates - the human biomonitoring approach.

    Matthias Wittassek;Holger Martin Koch;Jürgen Angerer;Thomas Brüning

  • Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women

    Leila Dorling;Sara Carvalho;Jamie Allen

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants

    Nasim Mavaddat;Paul D.P. Pharoah;Kyriaki Michailidou;Jonathan Tyrer

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Felix R. Day;Deborah J. Thompson;Hannes Helgason;Hannes Helgason;Daniel I. Chasman

  • MicroRNA related polymorphisms and breast cancer risk

    Sofia Khan;Dario Greco;Dario Greco;Kyriaki Michailidou;Roger L. Milne;Roger L. Milne

  • Cigarette smoking and lung cancer – relative risk estimates for the major histological types from a pooled analysis of case-control studies

    Beate Pesch;Benjamin Kendzia;Per Gustavsson;Karl Heinz Jöckel

  • Genome-wide association studies identify four ER negative-specific breast cancer risk loci

    Montserrat Garcia-Closas;Fergus J. Couch;Sara Lindstrom;Kyriaki Michailidou

  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

    Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  • Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

    Haoyu Zhang;Haoyu Zhang;Thomas U. Ahearn;Julie Lecarpentier;Daniel Barnes

  • Identifying sources of phthalate exposure with human biomonitoring: results of a 48h fasting study with urine collection and personal activity patterns.

    Holger M. Koch;Matthew Lorber;Krista L.Y. Christensen;Claudia Pälmke

  • Genome-wide association analysis identifies three new breast cancer susceptibility loci

    Maya Ghoussaini;Olivia Fletcher;Kyriaki Michailidou;Clare Turnbull

  • Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.

    Yan Guo;Shaneda Warren Andersen;Xiao-Ou Shu;Kyriaki Michailidou

  • Markers of genetic susceptibility in human environmental hygiene and toxicology: The role of selected CYP, NAT and GST genes

    Ricarda Thier;Thomas Brüning;Peter H. Roos;Hans-Peter Rihs

  • Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

    Felix R. Day;Katherine S. Ruth;Deborah J. Thompson;Kathryn L. Lunetta

Frequent Co-Authors

Hiltrud Brauch
Hiltrud Brauch German Cancer Research Center
Graham G. Giles
Graham G. Giles University of Melbourne
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Peter A. Fasching
Peter A. Fasching University of Erlangen-Nuremberg
Ute Hamann
Ute Hamann German Cancer Research Center
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Stig E. Bojesen
Stig E. Bojesen University of Copenhagen
Irene L. Andrulis
Irene L. Andrulis University of Toronto
Barbara Burwinkel
Barbara Burwinkel Heidelberg University
Melissa C. Southey
Melissa C. Southey Monash University

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