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Research.com Recognitions

  • 2026 - Research.com Medicine in United Kingdom Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in United Kingdom Leader Award
  • 2023 - Research.com Medicine in United Kingdom Leader Award
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Douglas F. Easton is affiliated with the University of Cambridge in the United Kingdom. Their research primarily focuses on the field of Biochemistry, Genetics, and Molecular Biology, with a significant portion of work in Genetics, Molecular Biology, Cancer Research, Immunology, and Oncology.

The main topics of their work include:

  • BRCA gene mutations in cancer
  • Genetic Associations and Epidemiology
  • Nutrition, Genetics, and Disease
  • Cancer Genomics and Diagnostics
  • DNA Repair Mechanisms
  • Bioinformatics and Genomic Networks
  • Biological Research and Disease Studies

Douglas F. Easton has contributed to multiple recent papers covering a range of topics in cancer genetics and epidemiology. Notable publications include:

  • "Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies?" (2021, Cancers)
  • "A Genome-wide Association Study of Early-Onset Breast Cancer Identifies PFKM as a Novel Breast Cancer Gene and Supports a Common Genetic Spectrum for Breast Cancer at Any Age" (2021, UNC Libraries)
  • "BOADICEA model: updates to the BRCA2 breast cancer risks for ages 60 years and older" (2024, BJC Reports)
  • "Polymorphism in the IL18 Gene and Epithelial Ovarian Cancer in Non-Hispanic White Women" (2020, UNC Libraries)
  • "The age-related deceleration of clonal haematopoiesis in 420,000 healthy adults" (2023, bioRxiv [Cold Spring Harbor Laboratory])

Easton frequently publishes in venues such as UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), Cancers, BJC Reports, and EBioMedicine.

Collaborations are an important aspect of Easton's research. Frequent co-authors include:

  • Joe Dennis
  • Kyriaki Michailidou
  • Kamila Czene
  • Manjeet K. Bolla
  • Melissa C. Southey

Among recognitions, Douglas F. Easton has been named a Fellow of The Academy of Medical Sciences, United Kingdom.

Best Publications

  • Identification of the breast cancer susceptibility gene BRCA2

    Wooster R;Bignell G;Lancaster J;Swift S

  • Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies

    A. Antoniou;P.D.P. Pharoah;S. Narod;H.A. Risch

  • Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families

    D Ford;D F Easton;M Stratton;S Narod

  • Patterns of somatic mutation in human cancer genomes

    Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Genome-wide association study identifies novel breast cancer susceptibility loci

    Douglas F. Easton;Karen A. Pooley;Alison M. Dunning;Paul D. P. Pharoah

  • Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.

    Brinda Ravikumar;Coralie Vacher;Zdenek Berger;Janet E Davies

  • Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13

    Richard Wooster;Susan L. Neuhausen;Jonathan Mangion;Yvette Quirk

  • Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

    Karoline B. Kuchenbaecker;Karoline B. Kuchenbaecker;John L. Hopper;Daniel R. Barnes;Kelly-Anne Phillips

  • Risks of cancer in BRCA1-mutation carriers

    Ford D;Easton Df;Bishop Dt;Narod Sa

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.

    D F Easton;D Ford;D T Bishop

  • The landscape of cancer genes and mutational processes in breast cancer

    Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo

  • Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.

    D F Easton;D T Bishop;D Ford;G P Crockford

  • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

    Fiona M. Blows;Kristy E. Driver;Marjanka K. Schmidt;Annegien Broeks

  • The evolutionary history of lethal metastatic prostate cancer.

    Gunes Gundem;Peter Van Loo;Peter Van Loo;Peter Van Loo;Barbara Kremeyer;Ludmil B. Alexandrov

  • Cancer Incidence in BRCA1 Mutation Carriers

    Deborah Thompson;Douglas F Easton

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

    Hanne Meijers-Heijboer;Ans van den Ouweland;Jan Klijn;Marijke Wasielewski

  • Erratum: Identification of the breast cancer susceptibility gene BRCA2

    Richard Wooster;Graham Bignell;Jonathan Lancaster;Sally Swift

Frequent Co-Authors

Graham G. Giles
Graham G. Giles University of Melbourne
Paul D.P. Pharoah
Paul D.P. Pharoah University of Cambridge
Alison M. Dunning
Alison M. Dunning University of Cambridge
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Melissa C. Southey
Melissa C. Southey Monash University
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Irene L. Andrulis
Irene L. Andrulis University of Toronto
Fergus J. Couch
Fergus J. Couch Mayo Clinic
Georgia Chenevix-Trench
Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute
John L. Hopper
John L. Hopper University of Melbourne

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