H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Medicine D-index 165 Citations 117,115 626 World Ranking 226 National Ranking 27

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Internal medicine

His primary areas of investigation include Breast cancer, Genetics, Internal medicine, Cancer and Oncology. His studies in Breast cancer integrate themes in fields like Cancer research, Genetic predisposition, Ovarian cancer, Genotype and Risk factor. His study in Genome-wide association study, Locus, Allele, Gene and Mutation is carried out as part of his Genetics studies.

He combines subjects such as Disease, Case-control study, Genetic association and Bioinformatics with his study of Genome-wide association study. His Internal medicine research is multidisciplinary, relying on both Penetrance, Endocrinology, Gynecology and Pathology. His Oncology study combines topics from a wide range of disciplines, such as Odds ratio, Relative risk, Estrogen receptor, Hazard ratio and Prospective cohort study.

His most cited work include:

  • Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies (2742 citations)
  • Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families (2565 citations)
  • Patterns of somatic mutation in human cancer genomes (2497 citations)

What are the main themes of his work throughout his whole career to date?

Douglas F. Easton focuses on Breast cancer, Internal medicine, Genetics, Oncology and Genome-wide association study. His Breast cancer study results in a more complete grasp of Cancer. His Internal medicine research integrates issues from Endocrinology and Gynecology.

In his research on the topic of Oncology, Proportional hazards model is strongly related with Hazard ratio. Douglas F. Easton has included themes like Disease, Genetic predisposition, Bioinformatics, Genotyping and Genetic association in his Genome-wide association study study. His Single-nucleotide polymorphism research includes themes of Endometrial cancer and Candidate gene.

He most often published in these fields:

  • Breast cancer (55.05%)
  • Internal medicine (43.79%)
  • Genetics (38.44%)

What were the highlights of his more recent work (between 2017-2021)?

  • Breast cancer (55.05%)
  • Internal medicine (43.79%)
  • Oncology (37.17%)

In recent papers he was focusing on the following fields of study:

Douglas F. Easton spends much of his time researching Breast cancer, Internal medicine, Oncology, Genome-wide association study and Genetics. He does research in Breast cancer, focusing on Estrogen receptor specifically. Douglas F. Easton combines topics linked to Germline mutation with his work on Internal medicine.

His work deals with themes such as Mendelian randomization, Germline, Hazard ratio, Single-nucleotide polymorphism and Prostate cancer, which intersect with Oncology. The Genome-wide association study study combines topics in areas such as Transcriptome, Genetic predisposition, Genetic association and Medical genetics. His specific area of interest is Cancer, where Douglas F. Easton studies Colorectal cancer.

Between 2017 and 2021, his most popular works were:

  • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (268 citations)
  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes (257 citations)
  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (145 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Internal medicine

His primary scientific interests are in Breast cancer, Internal medicine, Genome-wide association study, Oncology and Genetics. His Breast cancer research is mostly focused on the topic Estrogen receptor. His works in Case-control study, Cancer, Ovarian cancer, Cohort and Age of onset are all subjects of inquiry into Internal medicine.

His biological study spans a wide range of topics, including Quantitative trait locus, Genetic association and Medical genetics. The various areas that Douglas F. Easton examines in his Oncology study include Germline mutation, Hazard ratio, Confidence interval, Prospective cohort study and Prostate cancer. His Germline mutation research incorporates themes from Penetrance and Pancreatic cancer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies

A Antoniou;Pdp Pharoah;S Narod;HA Risch.
American Journal of Human Genetics (2003)

4089 Citations

Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families

D Ford;D F Easton;M Stratton;S Narod.
American Journal of Human Genetics (1998)

3690 Citations

Patterns of somatic mutation in human cancer genomes

Christopher Greenman;Philip Stephens;Raffaella Smith;Gillian L. Dalgliesh.
Nature (2007)

3284 Citations

Genome-wide association study identifies novel breast cancer susceptibility loci

Douglas F. Easton;Karen A. Pooley;Alison M. Dunning;Paul D. P. Pharoah.
Nature (2007)

2560 Citations

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.

Brinda Ravikumar;Coralie Vacher;Zdenek Berger;Janet E Davies.
Nature Genetics (2004)

2467 Citations

Risks of cancer in BRCA1-mutation carriers

D. Ford;D.F. Easton;D.T. Bishop;S.A. Narod.
The Lancet (1994)

2272 Citations

Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.

D F Easton;D Ford;D T Bishop.
American Journal of Human Genetics (1995)

2037 Citations

Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.

D F Easton;D T Bishop;D Ford;G P Crockford.
American Journal of Human Genetics (1993)

1725 Citations

The landscape of cancer genes and mutational processes in breast cancer

Philip J. Stephens;Patrick S. Tarpey;Helen Davies;Peter Van Loo;Peter Van Loo.
Nature (2012)

1642 Citations

International network of cancer genome projects

Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker.
Nature (2010)

1460 Citations

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