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Genetics
UK
2024
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Genetics and Molecular Biology
UK
2024

D-Index & Metrics

Genetics

D-Index
129
Citations
68802
World Ranking
261
National Ranking
48

Medicine

D-Index
135
Citations
74966
World Ranking
2055
National Ranking
217

Research.com Recognitions

  • 2024 - Research.com Genetics in United Kingdom Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
  • 2023 - Research.com Genetics in United Kingdom Leader Award
  • 2017 - Fellow of the Royal Society, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Richard S. Houlston is affiliated with the Institute of Cancer Research in the United Kingdom. Their research spans areas within Biochemistry, Genetics and Molecular Biology, and Medicine, with significant focus on Genetics, Molecular Biology, Oncology, Cancer Research, and Pathology and Forensic Medicine.

The main topics covered in their research include:

  • Genetic Associations and Epidemiology
  • Genetic factors in colorectal cancer
  • Cancer Genomics and Diagnostics
  • Multiple Myeloma Research and Treatments
  • Epigenetics and DNA Methylation
  • BRCA gene mutations in cancer
  • Protein Degradation and Inhibitors

Frequent co-authors collaborating with Houlston include:

  • Philip Law
  • Amit Sud
  • Clare Turnbull
  • Ben Kinnersley
  • Alex J. Cornish

The scientist has published extensively in several venues, notably:

  • Nature Communications (13 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (11 publications)
  • Blood Cancer Journal (9 publications)
  • British Journal of Cancer (7 publications)
  • Nature (6 publications)

Among recent papers authored or co-authored by Houlston are:

  • Lung adenocarcinoma promotion by air pollutants, 2023, Nature
  • Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic, 2020, Annals of Oncology
  • Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study, 2020, The Lancet Oncology
  • Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D, 2020, JNCI Journal of the National Cancer Institute
  • Universal weekly testing as the UK COVID-19 lockdown exit strategy, 2020, The Lancet

Houlston has been recognized by election to prestigious fellowships, including:

  • Fellow of the Royal Society, United Kingdom (2017)
  • Fellow of The Academy of Medical Sciences, United Kingdom

Best Publications

  • Systematic Review of Microsatellite Instability and Colorectal Cancer Prognosis

    S. Popat;R. Hubner;R.S. Houlston

  • Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer.

    Tomlinson Ip;Alam Na;Rowan Aj;Barclay E

  • Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

    Christopher I. Amos;Xifeng Wu;Peter Broderick;Ivan P. Gorlov

  • Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

    Hanne Meijers-Heijboer;Ans van den Ouweland;Jan Klijn;Marijke Wasielewski

  • Mutations in the SMAD4/DPC4 gene in juvenile polyposis.

    James R. Howe;Stina Roth;John C. Ringold;Robert W. Summers

  • The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

    D I Swerdlow;M V Holmes;K B Kuchenbaecker

  • Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

    Claire Palles;Jean-Baptiste Cazier;Kimberley M Howarth;Enric Domingo

  • A systematic review and meta-analysis of familial colorectal cancer risk

    Louise E Johns;Richard S Houlston

  • Frequency and Spectrum of Cancers in the Peutz-Jeghers Syndrome

    Nicholas Hearle;Valérie Schumacher;Fred H. Menko;Sylviane Olschwang

  • A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21.

    Ian Tomlinson;Ian Tomlinson;Emily Webb;Luis Carvajal-Carmona;Peter Broderick

  • Genome-wide association study identifies five susceptibility loci for glioma

    Sanjay Shete;Fay J. Hosking;Lindsay B. Robertson;Sara E. Dobbins

  • Genome-wide association study identifies five new breast cancer susceptibility loci

    Clare Turnbull;Shahana Ahmed;Jonathan Morrison;David Pernet

  • Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

    James D McKay;Rayjean J Hung;Younghun Han;Xuchen Zong

  • Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.

    Albert Tenesa;Susan M Farrington;James G D Prendergast;Mary E Porteous

  • A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

    Ian P.M. Tomlinson;Emily Webb;Luis Carvajal-Carmona;Peter Broderick

  • Common 5p15.33 and 6p21.33 variants influence lung cancer risk.

    Yufei Wang;Peter Broderick;Emily Webb;Xifeng Wu

  • A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

    Peter Broderick;Luis Carvajal-Carmona;Luis Carvajal-Carmona;Alan M. Pittman;Emily Webb

  • Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

    Richard S. Houlston;Emily Webb;Peter Broderick;Alan M. Pittman

  • Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis.

    Sanjay Popat;Athena Matakidou;Richard S. Houlston

  • A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma.

    Maria Teresa Landi;Nilanjan Chatterjee;Kai Yu;Lynn R. Goldin

Frequent Co-Authors

Ian Tomlinson
Ian Tomlinson University of Oxford
Peter Broderick
Peter Broderick Institute of Cancer Research
Kari Hemminki
Kari Hemminki Charles University
Christopher I. Amos
Christopher I. Amos Baylor College of Medicine
Malcolm G. Dunlop
Malcolm G. Dunlop University of Edinburgh
Melissa L. Bondy
Melissa L. Bondy Stanford University
Anthony J. Swerdlow
Anthony J. Swerdlow Institute of Cancer Research
Daniel Catovsky
Daniel Catovsky Institute of Cancer Research
Douglas F. Easton
Douglas F. Easton University of Cambridge
Per Hoffmann
Per Hoffmann University of Bonn

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