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Medicine
Australia
2026

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Best Scientists

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172
Citations
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National Ranking
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Medicine

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178
Citations
135119
World Ranking
388
National Ranking
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Research.com Recognitions

  • 2026 - Research.com Medicine in Australia Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in Australia Leader Award
  • 2023 - Research.com Medicine in Australia Leader Award
  • 2022 - Research.com Medicine in Australia Leader Award

Overview

Graham G. Giles is affiliated with the University of Melbourne in Australia and has contributed extensively to research in medicine and related biological sciences. Their work spans multiple disciplines, with a strong focus on genetics and oncology as reflected in the main fields and subfields of study.

The primary fields of study associated with their research include Medicine and Biochemistry, Genetics and Molecular Biology. Within these areas, Giles's subfield contributions are concentrated in Genetics, Oncology, Molecular Biology, Pathology and Forensic Medicine, and Cancer Research.

The scientist's research topics comprise genetic associations and epidemiology, genetic factors in colorectal cancer, BRCA gene mutations in cancer, epigenetics and DNA methylation, cancer risks and factors, colorectal cancer screening and detection, and nutritional studies and diet. These topics highlight a focus on understanding genetic influences and molecular mechanisms related to cancer development and prevention.

Recent publications provide insight into the scope and impact of their work. Notable papers include:

  • Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women, 2021, New England Journal of Medicine
  • Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis, 2020, Nature Communications
  • Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses, 2020, Nature Genetics
  • Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction, 2021, Nature Genetics
  • Genetic insights into biological mechanisms governing human ovarian ageing, 2021, Nature

The researcher has collaborated frequently with peers such as Roger L. Milne, Melissa C. Southey, John L. Hopper, Loïc Le Marchand, and Hermann Brenner, demonstrating a network of co-authorship in their field.

Publication venues where Giles has appeared most often include:

  • UNC Libraries
  • Cancer Epidemiology Biomarkers & Prevention
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Epidemiology
  • International Journal of Cancer

Best Publications

  • Body-Mass Index and Mortality among 1.46 Million White Adults

    Amy Berrington De Gonzalez;Patricia Hartge;James R. Cerhan;Alan J. Flint

  • REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

    Nilah M M. Ioannidis;Joseph H H. Rothstein;Joseph H H. Rothstein;Vikas Pejaver;Sumit Middha

  • Genome-wide association study identifies novel breast cancer susceptibility loci

    Douglas F. Easton;Karen A. Pooley;Alison M. Dunning;Paul D. P. Pharoah

  • Cancer risk in 680 000 people exposed to computed tomography scans in childhood or adolescence: data linkage study of 11 million Australians

    John D Mathews;Anna V Forsythe;Zoe Brady;Martin W Butler

  • Socioeconomic status and the 25 × 25 risk factors as determinants of premature mortality: a multicohort study and meta-analysis of 1·7 million men and women

    Silvia Stringhini;Cristian Carmeli;Markus Jokela;Mauricio Avendaño;Mauricio Avendaño

  • Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies

    Fiona M. Blows;Kristy E. Driver;Marjanka K. Schmidt;Annegien Broeks

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk

    Kyriaki Michailidou;Per Hall;Anna Gonzalez-Neira;Maya Ghoussaini

  • RAD51B in Familial Breast Cancer

    Liisa M. Pelttari;Sofia Khan;Mikko Vuorela;Johanna I. Kiiski

  • Multiple newly identified loci associated with prostate cancer susceptibility.

    Rosalind A Eeles;Rosalind A Eeles;Zsofia Kote-Jarai;Graham G Giles;Graham G Giles;Ali Amin Al Olama

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies

    Xiaohong R. Yang;Jenny Chang-Claude;Ellen L. Goode;Fergus J. Couch

  • Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

    Ganna Chornokur;Hui-Yi Lin;Jonathan P. Tyrer;Kate Lawrenson

  • Iron-overload-related disease in HFE hereditary hemochromatosis

    Katrina J. Allen;Lyle C. Gurrin;Clare C. Constantine;Nicholas J. Osborne

  • Non-melanoma skin cancer in Australia: the 2002 national survey and trends since 1985.

    Margaret Staples;Mark Elwood;Robert Charles Burton;Jodie L Williams

  • Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

    Fredrick R. Schumacher;Ali Amin Al Olama;Sonja I. Berndt;Sara Benlloch

  • Heritability of mammographic density, a risk factor for breast cancer.

    Norman F Boyd;Gillian S Dite;Jennifer Stone;Anoma Gunasekara

  • Breast Cancer Risk Genes - Association Analysis in More than 113,000 Women

    Leila Dorling;Sara Carvalho;Jamie Allen

  • A common coding variant in CASP8 is associated with breast cancer risk

    Angela Cox;Alison M. Dunning;Montserrat Garcia-Closas;Sabapathy Balasubramanian

  • The Anti Cancer Council of Victoria FFQ: relative validity of nutrient intakes compared with weighed food records in young to middle-aged women in a study of iron supplementation.

    Allison Hodge;Amanda J. Patterson;Wendy J. Brown;Paul Ireland

Frequent Co-Authors

Roger L. Milne
Roger L. Milne Cancer Council Victoria
John L. Hopper
John L. Hopper University of Melbourne
Melissa C. Southey
Melissa C. Southey Monash University
Dallas R. English
Dallas R. English University of Melbourne
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Hiltrud Brauch
Hiltrud Brauch German Cancer Research Center
Douglas F. Easton
Douglas F. Easton University of Cambridge
Paul D.P. Pharoah
Paul D.P. Pharoah University of Cambridge
Laura Baglietto
Laura Baglietto University of Pisa

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