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Michel R. Popoff

Michel R. Popoff

D-Index & Metrics

Microbiology

D-Index
79
Citations
19348
World Ranking
1234
National Ranking
72

Overview

Michel R. Popoff is affiliated with the Institut Pasteur in France, focusing primarily on research within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their scientific contributions encompass various subfields including Neurology, Molecular Biology, Infectious Diseases, Cellular and Molecular Neuroscience, and Immunology.

The research topics addressed by Michel R. Popoff reflect a concentration on neurological and infectious disease mechanisms, with notable themes including:

  • Botulinum Toxin and Related Neurological Disorders
  • Clostridium difficile and Clostridium perfringens research
  • Hereditary Neurological Disorders
  • Neurological disorders and treatments
  • Toxin Mechanisms and Immunotoxins
  • Streptococcal Infections and Treatments
  • Bacillus and Francisella bacterial research

Michel R. Popoff has published extensively, with research appearing in a range of scientific journals. Frequent publication venues include:

  • Toxins
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Veterinary Diagnostic Investigation
  • Toxicon
  • The FASEB Journal

Some recent papers include:

  • "Tetanus in animals", 2020, Journal of Veterinary Diagnostic Investigation
  • "Human Botulism in France, 1875-2016", 2020, Toxins
  • "Neuronal selectivity of botulinum neurotoxins", 2020, Toxicon
  • "Engineering Botulinum Neurotoxins for Enhanced Therapeutic Applications and Vaccine Development", 2020, Toxins
  • "Human peptide α-defensin-1 interferes with Clostridioides difficile toxins TcdA, TcdB, and CDT", 2020, The FASEB Journal

Collaborations have been a significant aspect of Michel R. Popoff's research activities. The scientist has frequently worked with other researchers, including:

  • Emmanuel Lemichez
  • Christine Rasetti-Escargueil
  • Daniel Ladant
  • Évelyne Benoit
  • Bernard Poulain

Best Publications

  • Clostridium perfringens: toxinotype and genotype

    Laetitia Petit;Maryse Gibert;Michel R. Popoff

  • Production of actin‐specific ADP‐ribosyltransferase (binary toxin) by strains of Clostridium difficile

    Simon Stubbs;Maja Rupnik;Maryse Gibert;Jon Brazier

  • Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

    Richard A. Stabler;Miao-Xia He;Lisa Dawson;Melissa Martin

  • Binary Bacterial Toxins: Biochemistry, Biology, and Applications of Common Clostridium and Bacillus Proteins

    Holger Barth;Klaus Aktories;Michel R. Popoff;Bradley G. Stiles

  • Beta2 toxin, a novel toxin produced by Clostridium perfringens.

    Maryse Gibert;Colette Jolivet-Renaud;Michel R. Popoff

  • Requirement of Rac1 and Rac2 expression by mature dendritic cells for T cell priming.

    Federica Benvenuti;Stephanie Hugues;Marita Walmsley;Sandra Ruf

  • Production of a complete binary toxin (actin-specific ADP-ribosyltransferase) by Clostridium difficile CD196

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  • Historical perspectives and guidelines for botulinum neurotoxin subtype nomenclature

    Michael W. Peck;Theresa J. Smith;Fabrizio Anniballi;John W. Austin

  • Prevalence of β2-Toxigenic Clostridium perfringens in Horses with Intestinal Disorders

    Cornelia Herholz;Raymond Miserez;Jacques Nicolet;Joachim Frey

  • Ras, Rap, and Rac Small GTP-binding Proteins Are Targets for Clostridium sordellii Lethal Toxin Glucosylation

    Michel R. Popoff;Esteban Chaves-Olarte;Emmanuel Lemichez;Emmanuel Lemichez;Christoph von Eichel-Streiber

  • Clostridium Perfringens Epsilon-Toxin Shows Structural Similarity to the Pore-Forming Toxin Aerolysin

    Ambrose R Cole;Maryse Gibert;Michel Popoff;David S Moss

  • Clostridium perfringens Epsilon Toxin Induces a Rapid Change of Cell Membrane Permeability to Ions and Forms Channels in Artificial Lipid Bilayers

    Laetitia Petit;Elke Maier;Maryse Gibert;Michel R. Popoff

  • Clostridium perfringens epsilon-toxin acts on MDCK cells by forming a large membrane complex.

    Laetitia Petit;Maryse Gibert;Daniel Gillet;Christine Laurent-Winter

  • Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors.

    Stéphane Pelletier;François Duhamel;Philippe Coulombe;Michel R. Popoff

  • Dynamin Inhibition Blocks Botulinum Neurotoxin Type A Endocytosis in Neurons and Delays Botulism

    Callista B. Harper;Sally Martin;Tam H. Nguyen;Shari J. Daniels

  • Multifaceted role of Rho, Rac, Cdc42 and Ras in intercellular junctions, lessons from toxins.

    Michel R. Popoff;Blandine Geny

  • Genotyping and Phenotyping of Beta2-Toxigenic Clostridium perfringens Fecal Isolates Associated with Gastrointestinal Diseases in Piglets

    Michael Waters;Amanda Savoie;Helen S. Garmory;Dawn Bueschel

  • Bacterial protein toxins and lipids: pore formation or toxin entry into cells.

    Blandine Geny;Michel R. Popoff

  • Nucleotide sequence of the gene encoding Clostridium botulinum neurotoxin type D.

    Thomas Binz;Hisao Kurazono;Michel R. Popoff;Melvin W. Eklund

  • Identification and characterization of functional subunits of Clostridium botulinum type A progenitor toxin involved in binding to intestinal microvilli and erythrocytes.

    Yukako Fujinaga;Kaoru Inoue;Takako Nomura;Junzo Sasaki

  • Nucleotide sequence of Clostridium botulinum C1 neurotoxin

    Daniel Hauser;Melvin W. Eklund;Hisao Kurazono;Thomas Binz

Frequent Co-Authors

Holger Barth
Holger Barth University of Ulm
Emmanuel Lemichez
Emmanuel Lemichez Institut Pasteur
Roland Benz
Roland Benz Jacobs University
Patrice Boquet
Patrice Boquet Grenoble Alpes University
Klaus Aktories
Klaus Aktories University of Freiburg
Jordi Molgó
Jordi Molgó Centre national de la recherche scientifique, CNRS
Christiane Bouchier
Christiane Bouchier Institut Pasteur
Patrick Fach
Patrick Fach French Agency for Food, Environmental and Occupational Health & Safety
Richard W. Titball
Richard W. Titball University of Exeter
Joachim Frey
Joachim Frey University of Bern

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