Holger Barth

Overview

Best Publications

• Binary Bacterial Toxins: Biochemistry, Biology, and Applications of Common Clostridium and Bacillus Proteins

  Holger Barth;Klaus Aktories;Michel R. Popoff;Bradley G. Stiles

  531
  Citations

• Ephrin-A5 Induces Collapse of Growth Cones by Activating Rho and Rho Kinase

  Siegfried Wahl;Holger Barth;Thomas Ciossek;Klaus Aktories

  525
  Citations

• Cellular Uptake of Clostridium botulinum C2 Toxin Requires Oligomerization and Acidification

  Holger Barth;Dagmar Blöcker;Joachim Behlke;Wilma Bergsma-Schutter

  244
  Citations

• The N-Terminal Part of the Enzyme Component (C2I) of the Binary Clostridium botulinum C2 Toxin Interacts with the Binding Component C2II and Functions as a Carrier System for a Rho ADP-Ribosylating C3-Like Fusion Toxin

  H. Barth;F. Hofmann;C. Olenik;I. Just

  235
  Citations

• Low pH-induced formation of ion channels by clostridium difficile toxin B in target cells.

  Holger Barth;Gunther Pfeifer;Fred Hofmann;Elke Maier

  209
  Citations

• Cellular uptake of Clostridium difficile toxin B. Translocation of the N-terminal catalytic domain into the cytosol of eukaryotic cells.

  Gunther Pfeifer;Jörg Schirmer;Jost Leemhuis;Christian Busch

  205
  Citations

• Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells.

  Bernd Nilius;Thomas Voets;Jean Prenen;Holger Barth

  187
  Citations

• The host cell chaperone Hsp90 is essential for translocation of the binary Clostridium botulinum C2 toxin into the cytosol.

  Gerd Haug;Jost Leemhuis;Dirk Tiemann;Dieter K. Meyer

  181
  Citations

• Characterization of the enzymatic component of the ADP-ribosyltransferase toxin CDTa from Clostridium difficile.

  Irene Gülke;Gunther Pfeifer;Jan Liese;Michaela Fritz

  176
  Citations

• Structure and action of the binary C2 toxin from Clostridium botulinum.

  Christian Schleberger;Henrike Hochmann;Holger Barth;Klaus Aktories

  164
  Citations

• Binding of Clostridium botulinum C2 Toxin to Asparagine-linked Complex and Hybrid Carbohydrates *

  Matthias Eckhardt;Holger Barth;Dagmar Blöcker;Klaus Aktories

  163
  Citations

• Requirement of Rac activity for maintenance of capillary endothelial barrier properties.

  J. Waschke;W. Baumgartner;R. H. Adamson;M. Zeng

  161
  Citations

• Rho and rho kinase modulation of barrier properties: cultured endothelial cells and intact microvessels of rats and mice

  R. H. Adamson;F. E. Curry;G. Adamson;B. Liu

  152
  Citations

• Characterization of the Catalytic Site of the ADP-Ribosyltransferase Clostridium botulinum C2 Toxin by Site-directed Mutagenesis

  Holger Barth;Jan C. Preiss;Fred Hofmann;Klaus Aktories

  141
  Citations

• Actin microfilaments facilitate the retrograde transport from the Golgi complex to the endoplasmic reticulum in mammalian cells.

  Ferran Valderrama;Juan M. Durán;Teresa Babià;Holger Barth

  133
  Citations

• Membrane Translocation of Binary Actin-ADP-Ribosylating Toxins from Clostridium difficile and Clostridium perfringens Is Facilitated by Cyclophilin A and Hsp90

  Eva Kaiser;Claudia Kroll;Katharina Ernst;Carsten Schwan

  124
  Citations

• cAMP protects endothelial barrier functions by preventing Rac-1 inhibition

  J. Waschke;D. Drenckhahn;R. H. Adamson;H. Barth

  120
  Citations

• Changes and Regulation of the C5a Receptor on Neutrophils during Septic Shock in Humans

  Heike Unnewehr;Daniel Rittirsch;J. Vidya Sarma;Firas Zetoune

  118
  Citations

• Cellular Uptake of the Clostridium perfringens Binary Iota-Toxin

  Dagmar Blöcker;Joachim Behlke;Klaus Aktories;Holger Barth

  116
  Citations

• The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells

  Manuel Schuster;Leonie Schnell;Peter Feigl;Carina Birkhofer

  38
  Citations