World's Best Scientists 2026 revealed!
Holger Barth

Holger Barth

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
9976
World Ranking
11060
National Ranking
791

Holger Barth publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Holger Barth sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 209 publications — 53rd percentile

53% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Holger Barth D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Holger Barth sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 62 D-Index — 46th percentile

46% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Holger Barth is affiliated with the University of Ulm in Germany. Their research primarily spans Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology.

Their work covers several subfields, including Infectious Diseases, Immunology, Molecular Biology, Microbiology, and Endocrinology. These areas reflect a focus on understanding disease mechanisms, immune responses, and molecular processes.

Key topics addressed in their research include:

  • Clostridium difficile and Clostridium perfringens research
  • Toxin Mechanisms and Immunotoxins
  • Viral gastroenteritis research and epidemiology
  • Bacterial Infections and Vaccines
  • Escherichia coli research studies
  • Antimicrobial Peptides and Activities
  • Botulinum Toxin and Related Neurological Disorders

Notable recent publications by Holger Barth include:

  • "Nanodiamond Theranostic for Light-Controlled Intracellular Heating and Nanoscale Temperature Sensing" (2021), published in Nano Letters
  • "Human peptide α-defensin-1 interferes with Clostridioides difficile toxins TcdA, TcdB, and CDT" (2020), published in The FASEB Journal
  • "In situ monitoring of Lentilactobacillus parabuchneri biofilm formation via real-time infrared spectroscopy" (2022), published in npj Biofilms and Microbiomes
  • "Human α-Defensin-5 Efficiently Neutralizes Clostridioides difficile Toxins TcdA, TcdB, and CDT" (2020), published in Frontiers in Pharmacology
  • "The cytotoxic effect of Clostridioides difficile pore-forming toxin CDTb" (2021), published in Biochimica et Biophysica Acta (BBA) - Biomembranes

Holger Barth has collaborated extensively with several researchers, including:

  • Panagiotis Papatheodorou
  • Stephan Fischer
  • Katharina Ernst
  • Joscha Borho
  • Sebastian Heber

Their research has been frequently published in the following venues:

  • Toxins
  • Frontiers in Pharmacology
  • Scientific Reports
  • Naunyn-Schmiedeberg's Archives of Pharmacology
  • International Journal of Molecular Sciences

Best Publications

  • Binary Bacterial Toxins: Biochemistry, Biology, and Applications of Common Clostridium and Bacillus Proteins

    Holger Barth;Klaus Aktories;Michel R. Popoff;Bradley G. Stiles

  • Ephrin-A5 Induces Collapse of Growth Cones by Activating Rho and Rho Kinase

    Siegfried Wahl;Holger Barth;Thomas Ciossek;Klaus Aktories

  • Cellular Uptake of Clostridium botulinum C2 Toxin Requires Oligomerization and Acidification

    Holger Barth;Dagmar Blöcker;Joachim Behlke;Wilma Bergsma-Schutter

  • The N-Terminal Part of the Enzyme Component (C2I) of the Binary Clostridium botulinum C2 Toxin Interacts with the Binding Component C2II and Functions as a Carrier System for a Rho ADP-Ribosylating C3-Like Fusion Toxin

    H. Barth;F. Hofmann;C. Olenik;I. Just

  • Low pH-induced formation of ion channels by clostridium difficile toxin B in target cells.

    Holger Barth;Gunther Pfeifer;Fred Hofmann;Elke Maier

  • Cellular uptake of Clostridium difficile toxin B. Translocation of the N-terminal catalytic domain into the cytosol of eukaryotic cells.

    Gunther Pfeifer;Jörg Schirmer;Jost Leemhuis;Christian Busch

  • Role of Rho and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells.

    Bernd Nilius;Thomas Voets;Jean Prenen;Holger Barth

  • The host cell chaperone Hsp90 is essential for translocation of the binary Clostridium botulinum C2 toxin into the cytosol.

    Gerd Haug;Jost Leemhuis;Dirk Tiemann;Dieter K. Meyer

  • Characterization of the enzymatic component of the ADP-ribosyltransferase toxin CDTa from Clostridium difficile.

    Irene Gülke;Gunther Pfeifer;Jan Liese;Michaela Fritz

  • Structure and action of the binary C2 toxin from Clostridium botulinum.

    Christian Schleberger;Henrike Hochmann;Holger Barth;Klaus Aktories

  • Binding of Clostridium botulinum C2 Toxin to Asparagine-linked Complex and Hybrid Carbohydrates *

    Matthias Eckhardt;Holger Barth;Dagmar Blöcker;Klaus Aktories

  • Requirement of Rac activity for maintenance of capillary endothelial barrier properties.

    J. Waschke;W. Baumgartner;R. H. Adamson;M. Zeng

  • Rho and rho kinase modulation of barrier properties: cultured endothelial cells and intact microvessels of rats and mice

    R. H. Adamson;F. E. Curry;G. Adamson;B. Liu

  • Characterization of the Catalytic Site of the ADP-Ribosyltransferase Clostridium botulinum C2 Toxin by Site-directed Mutagenesis

    Holger Barth;Jan C. Preiss;Fred Hofmann;Klaus Aktories

  • Actin microfilaments facilitate the retrograde transport from the Golgi complex to the endoplasmic reticulum in mammalian cells.

    Ferran Valderrama;Juan M. Durán;Teresa Babià;Holger Barth

  • Membrane Translocation of Binary Actin-ADP-Ribosylating Toxins from Clostridium difficile and Clostridium perfringens Is Facilitated by Cyclophilin A and Hsp90

    Eva Kaiser;Claudia Kroll;Katharina Ernst;Carsten Schwan

  • cAMP protects endothelial barrier functions by preventing Rac-1 inhibition

    J. Waschke;D. Drenckhahn;R. H. Adamson;H. Barth

  • Changes and Regulation of the C5a Receptor on Neutrophils during Septic Shock in Humans

    Heike Unnewehr;Daniel Rittirsch;J. Vidya Sarma;Firas Zetoune

  • Cellular Uptake of the Clostridium perfringens Binary Iota-Toxin

    Dagmar Blöcker;Joachim Behlke;Klaus Aktories;Holger Barth

  • The Hsp90 machinery facilitates the transport of diphtheria toxin into human cells

    Manuel Schuster;Leonie Schnell;Peter Feigl;Carina Birkhofer

Frequent Co-Authors

Klaus Aktories
Klaus Aktories University of Freiburg
Tanja Weil
Tanja Weil Max Planck Society
Michel R. Popoff
Michel R. Popoff Institut Pasteur
Roland Benz
Roland Benz Jacobs University
Cesare Montecucco
Cesare Montecucco University of Padua
Herbert Schmidt
Herbert Schmidt University of Hohenheim
Markus Huber-Lang
Markus Huber-Lang University of Ulm
Kaloian Koynov
Kaloian Koynov Max Planck Institute for Polymer Research
Boris Mizaikoff
Boris Mizaikoff University of Ulm
Fedor Jelezko
Fedor Jelezko University of Ulm

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