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Gonçalo J. L. Bernardes

Gonçalo J. L. Bernardes

D-Index & Metrics

Chemistry

D-Index
63
Citations
16690
World Ranking
8316
National Ranking
471

Research.com Recognitions

  • 2016 - Harrison-Meldola Memorial Prize, Royal Society of Chemistry (UK)

Overview

Gonçalo J. L. Bernardes is affiliated with the University of Cambridge in the United Kingdom. Their research spans multiple disciplines within biochemistry, genetics, and molecular biology, with significant contributions in medicine.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields of research focus on:

  • Molecular Biology
  • Organic Chemistry
  • Radiology, Nuclear Medicine and Imaging
  • Oncology
  • Biomedical Engineering

Bernardes's work covers various scientific topics, notably:

  • Click Chemistry and Applications
  • Monoclonal and Polyclonal Antibodies Research
  • Chemical Synthesis and Analysis
  • Peptidase Inhibition and Analysis
  • Glycosylation and Glycoproteins Research
  • Protein Degradation and Inhibitors
  • RNA and protein synthesis mechanisms

Their recent scientific papers demonstrate a variety of research directions, including:

  • Biomimetic peptide self-assembly for functional materials, 2020, Nature Reviews Chemistry
  • METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation, 2021, Molecular Cell
  • The role of reversible and irreversible covalent chemistry in targeted protein degradation, 2021, Cell chemical biology
  • Platinum-Triggered Bond-Cleavage of Pentynoyl Amide and N-Propargyl Handles for Drug-Activation, 2020, Journal of the American Chemical Society
  • Serine-Selective Bioconjugation, 2020, Journal of the American Chemical Society

Frequent coauthors in Bernardes's work include:

  • Francisco Corzana
  • Ana Guerreiro
  • Claudio D. Navo
  • Gonzalo Jiménez-Osés
  • Tiago Rodrigues

Their research is commonly published in several prominent scientific venues, such as:

  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Journal of the American Chemical Society
  • bioRxiv (Cold Spring Harbor Laboratory)
  • ACS Central Science

In 2016, Bernardes received the Harrison-Meldola Memorial Prize from the Royal Society of Chemistry (UK).

Best Publications

  • Advances in Chemical Protein Modification

    Omar Boutureira;Goncalo Lopes Bernardes;Goncalo Lopes Bernardes

  • Inverse electron demand Diels–Alder reactions in chemical biology

    B. L. Oliveira;Z. Guo;G. J. L. Bernardes;G. J. L. Bernardes

  • Chemical modification of proteins at cysteine: opportunities in chemistry and biology.

    Justin M. Chalker;Gonçalo J. L. Bernardes;Yuya A. Lin;Benjamin G. Davis

  • Site-selective protein-modification chemistry for basic biology and drug development

    Nikolaus Krall;Filipa P. da Cruz;Omar Boutureira;Gonçalo J. L. Bernardes;Gonçalo J. L. Bernardes

  • Developing drug molecules for therapy with carbon monoxide

    Carlos C. Romão;Walter A. Blättler;João D. Seixas;Gonçalo J. L. Bernardes

  • De novo design of potent and selective mimics of IL-2 and IL-15

    Daniel-Adriano Silva;Shawn Yu;Umut Y Ulge;Jamie B Spangler;Jamie B Spangler

  • Contemporary approaches to site-selective protein modification

    Emily A. Hoyt;Pedro M. S. D. Cal;Bruno L. Oliveira;Bruno L. Oliveira;Gonçalo J. L. Bernardes;Gonçalo J. L. Bernardes

  • Biomimetic peptide self-assembly for functional materials

    Aviad Levin;Tuuli A. Hakala;Lee Schnaider;Gonçalo J. L. Bernardes;Gonçalo J. L. Bernardes

  • Allyl Sulfides Are Privileged Substrates in Aqueous Cross-Metathesis: Application to Site-Selective Protein Modification

    Yuya A. Lin;Justin M. Chalker;Nicola Floyd;Gonçalo J. L. Bernardes

  • Facile conversion of cysteine and alkyl cysteines to dehydroalanine on protein surfaces: versatile and switchable access to functionalized proteins.

    Gonçalo J. L. Bernardes;Justin M. Chalker;James C. Errey;Benjamin G. Davis

  • Methods for converting cysteine to dehydroalanine on peptides and proteins

    Justin M. Chalker;Smita B. Gunnoo;Omar Boutureira;Stefanie C. Gerstberger

  • A "tag-and-modify" approach to site-selective protein modification.

    Justin M. Chalker;Gonçalo J. L. Bernardes;Benjamin G. Davis

  • Carbon-monoxide-releasing molecules for the delivery of therapeutic CO in vivo.

    Sandra García-Gallego;Gonçalo J. L. Bernardes;Gonçalo J. L. Bernardes

  • Sulfur‐Limonene Polysulfide: A Material Synthesized Entirely from Industrial By‐Products and Its Use in Removing Toxic Metals from Water and Soil

    Michael P. Crockett;Austin M. Evans;Max J. H. Worthington;Inês S. Albuquerque

  • A small-molecule drug conjugate for the treatment of carbonic anhydrase IX expressing tumors.

    Nikolaus Krall;Francesca Pretto;Willy Decurtins;Gonçalo J. L. Bernardes;Gonçalo J. L. Bernardes;Gonçalo J. L. Bernardes

  • Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity

    Tom H. Wright;Ben J. Bower;Justin M. Chalker;Gonçalo J. L. Bernardes

  • Chemo- and Regioselective Lysine Modification on Native Proteins.

    Maria J Matos;Bruno L Oliveira;Nuria Martínez-Sáez;Ana Guerreiro

  • Laying Waste to Mercury: Inexpensive Sorbents Made from Sulfur and Recycled Cooking Oils

    Max J. H. Worthington;Renata L. Kucera;Inês S. Albuquerque;Christopher T. Gibson

  • Corm-3 Reactivity Toward Proteins: The Crystal Structure of a Ru(II) Dicarbonyl-Lysozyme Complex.

    Teresa Sacadura Santos-silva;Abhik Mukhopadhyay;João D. Seixas;Gonçalo J L Bernardes

  • From Disulfide‐ to Thioether‐Linked Glycoproteins

    Gonçalo J. L. Bernardes;Elizabeth J. Grayson;Sam Thompson;Justin M. Chalker

  • Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents

    Barbara Bernardim;Pedro M.S.D. Cal;Pedro M.S.D. Cal;Maria J. Matos;Bruno L. Oliveira

Frequent Co-Authors

Benjamin G. Davis
Benjamin G. Davis University of Oxford
Carlos C. Romão
Carlos C. Romão Universidade Nova de Lisboa
Maria João Matos
Maria João Matos University of Santiago de Compostela
Dario Neri
Dario Neri Philogen (Italy)
Tuomas P. J. Knowles
Tuomas P. J. Knowles University of Cambridge
Artur Cavaco-Paulo
Artur Cavaco-Paulo University of Minho
Michele Vendruscolo
Michele Vendruscolo University of Cambridge
Maria M. Mota
Maria M. Mota University of Lisbon
Joseph G. Shapter
Joseph G. Shapter University of Queensland

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