What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Oligonucleotide, Molecular biology, Biochemistry, Aptamer and DNA.
His research on Oligonucleotide also deals with topics like
- Gene expression together with Sense,
- Translation that connect with fields like Globin.
The study incorporates disciplines such as Recombinant DNA, Messenger RNA, Reticulocyte, Transcription and Ribosome in addition to Molecular biology.
His work on Nuclease, Phosphodiester bond and Antisense oligonucleotides as part of general Biochemistry study is frequently connected to Conjugate, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
His Aptamer research integrates issues from RNA, Systematic evolution of ligands by exponential enrichment and Surface plasmon resonance.
The various areas that Jean-Jacques Toulmé examines in his DNA study include Nucleic acid and RNase H.
His most cited work include:
- Specific regulation of gene expression by antisense, sense and antigene nucleic acids. (712 citations)
- Improved leishmanicidal effect of phosphorotioate antisense oligonucleotides by LDL-mediated delivery (224 citations)
- Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides (210 citations)
What are the main themes of his work throughout his whole career to date?
Jean-Jacques Toulmé mainly focuses on Oligonucleotide, RNA, Aptamer, Molecular biology and Biochemistry.
His Oligonucleotide research is under the purview of DNA.
His work carried out in the field of DNA brings together such families of science as Polynucleotide, Nucleic acid, Nucleotide and Sense.
His work deals with themes such as Base pair, Transcription and Cell biology, which intersect with RNA.
His studies in Aptamer integrate themes in fields like Biophysics, Computational biology, Combinatorial chemistry, Surface plasmon resonance and Systematic evolution of ligands by exponential enrichment.
His Molecular biology study integrates concerns from other disciplines, such as Complementary DNA, Messenger RNA and Reverse transcriptase, RNase H.
He most often published in these fields:
- Oligonucleotide (54.60%)
- RNA (51.72%)
- Aptamer (51.15%)
What were the highlights of his more recent work (between 2010-2021)?
- Aptamer (51.15%)
- Systematic evolution of ligands by exponential enrichment (27.01%)
- Oligonucleotide (54.60%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Aptamer, Systematic evolution of ligands by exponential enrichment, Oligonucleotide, RNA and Computational biology.
The Aptamer study combines topics in areas such as Biochemistry, Nucleic acid, Ligand, Biophysics and Combinatorial chemistry.
He usually deals with Nucleic acid and limits it to topics linked to DNA and Phosphodiester bond.
In the subject of general Systematic evolution of ligands by exponential enrichment, his work in SELEX Aptamer Technique is often linked to Selection, thereby combining diverse domains of study.
His Oligonucleotide study typically links adjacent topics like Biosensor.
His RNA research includes themes of Base pair and Surface plasmon resonance.
Between 2010 and 2021, his most popular works were:
- Riboswitches based on kissing complexes for the detection of small ligands. (37 citations)
- 99mTc-MAG3-Aptamer for Imaging Human Tumors Associated with High Level of Matrix Metalloprotease-9 (34 citations)
- Nucleic acids targeted to drugs: SELEX against a quadruplex ligand (31 citations)
In his most recent research, the most cited papers focused on:
Jean-Jacques Toulmé mostly deals with Aptamer, Systematic evolution of ligands by exponential enrichment, Surface plasmon resonance, RNA and Biophysics.
His research brings together the fields of Biochemistry and Aptamer.
His studies in Biochemistry integrate themes in fields like Molecular biology and Fluorescence anisotropy.
His Systematic evolution of ligands by exponential enrichment research integrates issues from Oligonucleotide, DNA, Nucleic acid and Small molecule.
His biological study spans a wide range of topics, including G-quadruplex and Binding site.
His RNA study frequently draws connections to other fields, such as Nucleotide.
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