World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
18669
World Ranking
5363
National Ranking
2544

Overview

Nicholas M. Dean is affiliated with Ionis Pharmaceuticals, located in the United States. The association with this organization situates the scientist within a leading biopharmaceutical company focused on discovering and developing RNA-targeted therapeutics.

There are no recent papers, co-authors, or publication records provided for Nicholas M. Dean. Similarly, no frequent publication venues, book publications, or distinct fields of study have been identified from the available data. This limits the possibility to detail specific research outputs or collaborations.

No particular main topics of work or subfields of study are associated with Nicholas M. Dean in the current information. Likewise, there is no record of awards or distinctions linked to this scientist in the data provided.

The professional profile of Nicholas M. Dean as represented here primarily highlights the connection to Ionis Pharmaceuticals in the United States without further elaboration on scientific contributions or subject matter expertise explicitly disclosed.

Best Publications

  • MicroRNA-143 regulates adipocyte differentiation.

    Christine Esau;Xiaolin Kang;Eigen Peralta;Elaine Hanson

  • Antisense oligonucleotide modulation of multidrug resistance-associated protein

    Edgardo Baracchini;C. Frank Bennett;Nicholas M. Dean

  • Efficient Reduction of Target RNAs by Small Interfering RNA and RNase H-dependent Antisense Agents: A COMPARATIVE ANALYSIS *

    Timothy A. Vickers;Seongjoon Koo;C. Frank Bennett;Stanley T. Crooke

  • Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-x(L) is an essential survival protein of human myeloma cells.

    Sophie Derenne;Brett Monia;Nicholas M. Dean;Jennifer K. Taylor

  • Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

    Jeremy R. Graff;Bruce W. Konicek;Thomas M. Vincent;Rebecca L. Lynch

  • Inhibition of protein kinase C-alpha expression in human A549 cells by antisense oligonucleotides inhibits induction of intercellular adhesion molecule 1 (ICAM-1) mRNA by phorbol esters.

    N M Dean;R McKay;T P Condon;C F Bennett

  • Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs.

    Yingqing Sun;Seongjoon Koo;Neill White;Eigen Peralta

  • Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides

    Nicholas M. Dean;Robert McKay

  • Antisense oligonucleotide-based therapeutics for cancer

    Nicholas M Dean;C Frank Bennett

  • Second Generation of Antisense Oligonucleotides: From Nuclease Resistance to Biological Efficacy in Animals.

    K.-H. Altmann;N. M. Dean;D. Fabbro;S. M. Freier

  • Specific Inhibition of PTEN Expression Reverses Hyperglycemia in Diabetic Mice

    Madeline Butler;Robert A. McKay;Ian J. Popoff;William A. Gaarde

  • Antisense modulation of bcl-x expression

    C. Frank Bennett;Nicholas M. Dean;Brett P. Monia;Brian J. Nickoloff

  • Characterization of a Potent and Specific Class of Antisense Oligonucleotide Inhibitor of Human Protein Kinase C-α Expression

    Robert A. McKay;Loren J. Miraglia;Lendell L. Cummins;Stephen R. Owens

  • Protein Kinase C-ζ Mediates Angiotensin II Activation of ERK1/2 in Vascular Smooth Muscle Cells

    Duan-Fang Liao;Brett Monia;Nicholas Dean;Bradford C. Berk

  • Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides

    Jennifer K. Taylor;Qing Qing Zhang;Jacqueline R. Wyatt;Nicholas M. Dean

  • Reduction of liver Fas expression by an antisense oligonucleotide protects mice from fulminant hepatitis

    Hong Zhang;Jesse Cook;Jeffrey Nickel;Rosie Yu

  • Inhibition of Growth of Human Tumor Cell Lines in Nude Mice by an Antisense Oligonucleotide Inhibitor of Protein Kinase C-α Expression

    Nicholas Dean;Robert McKay;Loren Miraglia;Randy Howard

  • SECOND-GENERATION ANTISENSE OLIGONUCLEOTIDES : STRUCTURE-ACTIVITY RELATIONSHIPS AND THE DESIGN OF IMPROVED SIGNAL-TRANSDUCTION INHIBITORS

    K H Altmann;D Fabbro;N M Dean;T Geiger

  • 5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells.

    Vanessa Taylor;Michelle Wong;Christian Brandts;Linda Reilly

  • Novel antisense oligonucleotides targeting TGF-beta inhibit in vivo scarring and improve surgical outcome

    M F Cordeiro;A Mead;R R Ali;R A Alexander

Frequent Co-Authors

C. Frank Bennett
C. Frank Bennett Ionis Pharmaceuticals (United States)
Brett P. Monia
Brett P. Monia Ionis Pharmaceuticals (United States)
Doriano Fabbro
Doriano Fabbro Novartis (Switzerland)
David Stokoe
David Stokoe Genentech
Muthiah Manoharan
Muthiah Manoharan Alnylam Pharmaceuticals (United States)
Olga Potapova
Olga Potapova National Institutes of Health
Dan Mercola
Dan Mercola University of California, Irvine
Robert M. McKay
Robert M. McKay Victoria University of Wellington
Marcel A. Müller
Marcel A. Müller Charité - University Medicine Berlin

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