World's Best Scientists 2026 revealed!
Karl-Heinz Altmann

Karl-Heinz Altmann

D-Index & Metrics

Chemistry

D-Index
55
Citations
11795
World Ranking
12046
National Ranking
221

Karl-Heinz Altmann publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Karl-Heinz Altmann sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 327 publications — 69th percentile

69% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Karl-Heinz Altmann D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Karl-Heinz Altmann sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 55 D-Index — 33rd percentile

33% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Karl-Heinz Altmann is affiliated with ETH Zurich in Switzerland and has an extensive body of research across several interconnected scientific fields. Their work spans Chemistry, Biochemistry, Genetics and Molecular Biology, and Materials Science, with significant contributions to subfields such as Organic Chemistry, Materials Chemistry, Molecular Biology, Pharmacology, and Oncology.

The scientist's research focuses on various topics including:

  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Synthetic Organic Chemistry Methods
  • Microbial Natural Products and Biosynthesis
  • Marine Sponges and Natural Products
  • Amino Acid Enzymes and Metabolism
  • Epigenetics and DNA Methylation

Altmann has published multiple papers in well-recognized scientific journals. Selected recent publications include:

  • "Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter," 2021, Cell Discovery
  • "Structural insight into the stabilization of microtubules by taxanes," 2023, eLife
  • "Synthesis and Structure-Activity Relationship Studies of C2-Modified Analogs of the Antimycobacterial Natural Product Pyridomycin," 2020, Journal of Medicinal Chemistry
  • "Small molecule inhibitors provide insights into the relevance of LAT1 and LAT2 in materno-foetal amino acid transport," 2020, Journal of Cellular and Molecular Medicine
  • "An RCM-Based Total Synthesis of the Antibiotic Disciformycin B," 2020, Angewandte Chemie International Edition

The scientist frequently publishes in several venues, including:

  • The Cambridge Structural Database
  • Chemistry - A European Journal
  • Angewandte Chemie International Edition
  • Angewandte Chemie
  • Journal of Medicinal Chemistry

Altmann's collaborative network includes co-authors they have worked with extensively, such as:

  • J. Fernando Díaz (16 joint publications)
  • Daniel Lucena-Agell (15 joint publications)
  • Jürg Gertsch (8 joint publications)
  • Christian P. Bold (7 joint publications)
  • Thomas M. Frossard (7 joint publications)

Best Publications

  • The ups and downs of nucleic acid duplex stability: Structure-stability studies on chemically-modified DNA:RNA duplexes

    Susan M. Freier;Karl-Heinz Altmann

  • Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents.

    Andrea E. Prota;Katja Bargsten;Didier Zurwerra;Jessica J. Field

  • Induction of Apoptosis in Small-Cell Lung Cancer Cells by an Antisense Oligodeoxynucleotide Targeting the Bcl-2 Coding Sequence

    Annemarie Ziegler;Gerd H. Luedke;Doriano Fabbro;Karl Heinz Altmann

  • Structural basis of small-molecule inhibition of human multidrug transporter ABCG2.

    Scott M. Jackson;Ioannis Manolaridis;Julia Kowal;Melanie Zechner

  • Second Generation of Antisense Oligonucleotides: From Nuclease Resistance to Biological Efficacy in Animals.

    K.-H. Altmann;N. M. Dean;D. Fabbro;S. M. Freier

  • Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects.

    Stefan Raduner;Adriana Majewska;Jian-Zhong Chen;Xiang-Qun Xie

  • A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs

    Andrea E. Prota;Katja Bargsten;J. Fernando Diaz;May Marsh

  • Puromycin-sensitive aminopeptidases

    Adriano Fontana;Daniel Beat Constam;Andreas Rudolf Tobler;Karl-Heinz Altmann

  • Epothilones and related structures--a new class of microtubule inhibitors with potent in vivo antitumor activity.

    Karl-Heinz Altmann;Markus Wartmann;Terence O’Reilly

  • GABA A receptors as in vivo substrate for the anxiolytic action of valerenic acid, a major constituent of valerian root extracts.

    Dietmar Benke;Andrea Barberis;Sascha Kopp;Karl Heinz Altmann

  • Template-Assembled Synthetic Proteins with 4-Helix-Bundle Topology - Total Chemical Synthesis and Conformational Studies

    Manfred Mutter;Gabriele G. Tuchscherer;Charleen Miller;Karl Heinz Altmann

  • SECOND-GENERATION ANTISENSE OLIGONUCLEOTIDES : STRUCTURE-ACTIVITY RELATIONSHIPS AND THE DESIGN OF IMPROVED SIGNAL-TRANSDUCTION INHIBITORS

    K H Altmann;D Fabbro;N M Dean;T Geiger

  • Backbone modifications in oligonucleotides and peptide nucleic acid systems

    Alain De Mesmaeker;Karl-Heinz Altmann;Adrian Waldner;Sebastian Wendeborn

  • Structural basis of microtubule stabilization by laulimalide and peloruside a.

    Andrea E. Prota;Katja Bargsten;Peter T. Northcote;May Marsh

  • Helix‐coil stability constants for the naturally occurring amino acids in water. XXIV. Half‐cystine parameters from random poly(hydroxybutylglutamine‐CO‐S‐methylthio‐L‐cysteine)

    J. Wójcik;K.-H. Altmann;H. A. Scheraga

  • 4′,6′-Methano carbocyclic thymidine: A conformationally constrained building block for oligonucleotides

    Karl-Heinz Altmann;Rudolf Kesselring;Eric Francotte;Grety Rihs

  • Chemical synthesis and biological properties of pyridine epothilones

    K C Nicolaou;R Scarpelli;B Bollbuck;B Werschkun

  • Chemical synthesis and biological evaluation of cis- and trans-12,13-cyclopropyl and 12,13-cyclobutyl epothilones and related pyridine side chain analogues.

    K. C. Nicolaou;K. C. Nicolaou;Kenji Namoto;Kenji Namoto;Andreas Ritzén;Andreas Ritzén;Trond Ulven;Trond Ulven

  • The chemistry and biology of epothilones--the wheel keeps turning.

    Karl-Heinz Altmann;Bernhard Pfeiffer;Stellios Arseniyadis;Benjamin A. Pratt

  • Microtubule-stabilizing agents: a growing class of important anticancer drugs.

    Unknown

  • Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts.

    Andrea Chicca;Stefan Raduner;Federica Pellati;Thomas Strompen

  • A collection of robust organic synthesis reactions for in silico molecule design.

    Markus Hartenfeller;Martin Eberle;Peter Meier;Cristina Nieto-Oberhuber

  • Second Generation Antisense Oligonucleotides—Inhibition of PKC-α and c-raf Kinase Expression by Chimeric Oligonucleotides Incorporating 6″-Substituted Carbocyclic Nucleosides and 2″-O-Ethylene Glycol Substituted Ribonucleosides

    Karl-Heinz Altmann;Pierre Martin;Nicholas M. Dean;Brett P. Mania

  • The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents.

    Teresa Carlomagno;Marcel J. J. Blommers;Jens Meiler;Jens Meiler;Wolfgang Jahnke

  • 1′,6′-methano carbocyclic thymidine: Synthesis, x-ray crystal structure, and effect on nucleic acid duplex stability

    Karl-Heinz Altmann;René Imwinkelried;Rudolf Kesselring;Grety Rihs

  • Switch Peptides: pH‐Induced α‐Helix to β‐Sheet Transitions of Bis‐amphiphilic Oligopeptides

    Manfred Mutter;R. Gassmann;U. Buttkus;K.-H. Altmann

  • Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin

    Marco Leonti;Laura Casu;Stefan Raduner;Filippo Cottiglia

  • Epothilone B and its analogs - a new family of anticancer agents.

    Unknown

  • Dual Recognition of Double-Stranded DNA by 2'-Aminoethoxy-Modified Oligonucleotides.

    Unknown

Frequent Co-Authors

Jürg Gertsch
Jürg Gertsch University of Bern
Michel O. Steinmetz
Michel O. Steinmetz Paul Scherrer Institute
Gerd Pluschke
Gerd Pluschke Swiss Tropical and Public Health Institute
K. C. Nicolaou
K. C. Nicolaou Rice University
Doriano Fabbro
Doriano Fabbro Novartis (Switzerland)
Stewart T. Cole
Stewart T. Cole Institut Pasteur
José Manuel Andreu
José Manuel Andreu Spanish National Research Council
Nicholas M. Dean
Nicholas M. Dean Ionis Pharmaceuticals (United States)

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