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Michel O. Steinmetz

Michel O. Steinmetz

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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
22003
World Ranking
4323
National Ranking
85

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Michel O. Steinmetz is affiliated with the Paul Scherrer Institute in Switzerland. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with extensive contributions in Molecular Biology, Cell Biology, Organic Chemistry, Materials Chemistry, and Cellular and Molecular Neuroscience.

Steinmetz's work focuses on various main topics including Microtubule and mitosis dynamics, Cancer therapeutics and mechanisms, Enzyme Structure and Function, Photosynthetic Processes and Mechanisms, Photochromic and Fluorescence Chemistry, Photoreceptor and optogenetics research, and 14-3-3 protein interactions.

The scientist has published multiple papers in high-impact journals. Selected recent papers include:

  • Comprehensive Analysis of Binding Sites in Tubulin, 2021, Angewandte Chemie International Edition
  • A Robust, GFP-Orthogonal Photoswitchable Inhibitor Scaffold Extends Optical Control over the Microtubule Cytoskeleton, 2020, Cell chemical biology
  • Structural model for differential cap maturation at growing microtubule ends, 2020, eLife
  • WDR90 is a centriolar microtubule wall protein important for centriole architecture integrity, 2020, eLife
  • Structural insight into the stabilization of microtubules by taxanes, 2023, eLife

Frequent co-authors include:

  • A.E. Prota (24 publications)
  • Tobias Mühlethaler (14 publications)
  • Maximilian Wranik (11 publications)
  • Natacha Olieric (11 publications)
  • Jörg Standfuss (11 publications)

Notable publication venues for Steinmetz feature several journals with repeated contributions:

  • bioRxiv (Cold Spring Harbor Laboratory), 13 publications
  • eLife, 5 publications
  • Nature Communications, 4 publications
  • Current Opinion in Structural Biology, 3 publications
  • The Journal of Cell Biology, 3 publications

Best Publications

  • Tracking the ends: a dynamic protein network controls the fate of microtubule tips

    Anna Akhmanova;Michel O. Steinmetz

  • Control of microtubule organization and dynamics: two ends in the limelight

    Anna Akhmanova;Michel O. Steinmetz

  • Structural basis for the regulation of tubulin by vinblastine

    Benoît Gigant;Chunguang Wang;Raimond B. G. Ravelli;Fanny Roussi

  • An EB1-Binding Motif Acts as a Microtubule Tip Localization Signal

    Srinivas Honnappa;Susana Montenegro Gouveia;Anke Weisbrich;Fred F. Damberger

  • Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents.

    Andrea E. Prota;Katja Bargsten;Didier Zurwerra;Jessica J. Field

  • STIM1 Is a MT-Plus-End-Tracking Protein Involved in Remodeling of the ER

    Ilya Grigoriev;Susana Montenegro Gouveia;Babet van der Vaart;Jeroen Demmers

  • Mammalian end binding proteins control persistent microtubule growth

    Yulia A. Komarova;Christian O. De Groot;Ilya Grigoriev;Susana Montenegro Gouveia

  • Microtubule-Targeting Agents: Strategies To Hijack the Cytoskeleton.

    Michel O. Steinmetz;Michel O. Steinmetz;Andrea E. Prota

  • ELM—the database of eukaryotic linear motifs

    Holger Dinkel;Sushama Michael;Robert J. Weatheritt;Norman E. Davey

  • Structural basis of the 9-fold symmetry of centrioles.

    Daiju Kitagawa;Ioannis Vakonakis;Ioannis Vakonakis;Natacha Olieric;Manuel Hilbert

  • Microtubule +TIPs at a glance.

    Anna Akhmanova;Michel O. Steinmetz

  • The Novel Microtubule-Destabilizing Drug BAL27862 Binds to the Colchicine Site of Tubulin with Distinct Effects on Microtubule Organization.

    Andrea E. Prota;Franck Danel;Felix Bachmann;Katja Bargsten

  • COMP-Ang1: A designed angiopoietin-1 variant with nonleaky angiogenic activity

    Chung Hyun Cho;Richard A. Kammerer;Hyuek Jong Lee;Michel O. Steinmetz

  • Motor Neuron Disease-Associated Mutant Vesicle-Associated Membrane Protein-Associated Protein (VAP) B Recruits Wild-Type VAPs into Endoplasmic Reticulum-Derived Tubular Aggregates

    Eva Teuling;Suaad Ahmed;Elize Haasdijk;Jeroen Demmers

  • A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs

    Andrea E. Prota;Katja Bargsten;J. Fernando Diaz;May Marsh

  • Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.

    Tobias Weinert;Natacha Olieric;Robert Cheng;Steffen Brünle

  • Isotope-tagged cross-linking reagents. A new tool in mass spectrometric protein interaction analysis.

    D. R. Müller;P. Schindler;H. Towbin;U. Wirth

  • Structural basis of tubulin tyrosination by tubulin tyrosine ligase

    Andrea E. Prota;Maria M. Magiera;Marijn Kuijpers;Katja Bargsten

  • Structure-function relationship of CAP-Gly domains

    Anke Weisbrich;Srinivas Honnappa;Rolf Jaussi;Oksana Okhrimenko

  • Cortexillins, Major Determinants of Cell Shape and Size, Are Actin-Bundling Proteins with a Parallel Coiled-Coil Tail

    Jan Faix;Michel Steinmetz;Heike Boves;Richard A. Kammerer

Frequent Co-Authors

Anna Akhmanova
Anna Akhmanova Utrecht University
Richard A. Kammerer
Richard A. Kammerer Paul Scherrer Institute
Ueli Aebi
Ueli Aebi University of Basel
Casper C. Hoogenraad
Casper C. Hoogenraad Utrecht University
Lukas C. Kapitein
Lukas C. Kapitein Utrecht University
Marc Baldus
Marc Baldus Utrecht University
Gebhard F. X. Schertler
Gebhard F. X. Schertler Paul Scherrer Institute
Pierre Gönczy
Pierre Gönczy École Polytechnique Fédérale de Lausanne
Beat H. Meier
Beat H. Meier ETH Zurich

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