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Best Scientists
2025
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Medicine
Finland
2026

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Best Scientists

D-Index
211
Citations
163245
World Ranking
188
National Ranking
2

Medicine

D-Index
214
Citations
166828
World Ranking
112
National Ranking
2

Research.com Recognitions

  • 2026 - Research.com Medicine in Finland Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Medicine in Finland Leader Award
  • 2023 - Research.com Medicine in Finland Leader Award
  • 2022 - Research.com Medicine in Finland Leader Award
  • 2013 - Member of the National Academy of Sciences
  • 2011 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Kari Alitalo is affiliated with the University of Helsinki in Finland and focuses on research primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their extensive work covers several subfields including Oncology, Molecular Biology, Cardiology and Cardiovascular Medicine, Surgery, and Cellular and Molecular Neuroscience.

The research topics frequently addressed by Alitalo include:

  • Lymphatic System and Diseases
  • Angiogenesis and VEGF in Cancer
  • Cerebrospinal fluid and hydrocephalus
  • Cancer Cells and Metastasis
  • Neonatal Respiratory Health Research
  • Cardiac Fibrosis and Remodeling
  • Lipid metabolism and disorders

Several recent publications showcase Alitalo's work across various venues, including:

  • "VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours" (2020), published in Nature
  • "Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span" (2021), published in Science
  • "NOTUM from Apc-mutant cells biases clonal competition to initiate cancer" (2021), published in Nature
  • "Lymphatic Malformations: Genetics, Mechanisms and Therapeutic Strategies" (2021), published in Circulation Research
  • "Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2 - implications for microvascular inflammation and hypercoagulopathy in COVID-19" (2020), published in bioRxiv (Cold Spring Harbor Laboratory)

Alitalo's publications frequently appear in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Cardiovascular Research
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Nature Communications

Frequent co-authors of Kari Alitalo include:

  • Riikka Kivelä
  • Karthik Amudhala Hemanthakumar
  • Pauliina Kallio
  • Salli Antila
  • Andrey Anisimov

Over the course of their career, Alitalo has been recognized by election to several prestigious organizations, including being named a Member of the National Academy of Sciences in 2013, a Member of Academia Europaea in 2011, and a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

    Holger Gerhardt;Matthew Golding;Marcus Fruttiger;Christiana Ruhrberg

  • Molecular regulation of angiogenesis and lymphangiogenesis.

    Ralf H. Adams;Kari Alitalo

  • A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

    V Joukov;K Pajusola;A Kaipainen;D Chilov

  • Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

    Mihaela Skobe;Thomas Hawighorst;David G. Jackson;Remko Prevo

  • Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.

    Manfred Schwab;Kari Alitalo;Karl Heinz Klempnauer;Harold E. Varmus

  • A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

    Aleksanteri Aspelund;Salli Antila;Steven T. Proulx;Tine Veronica Karlsen

  • Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

    Arja Kaipainen;Jaana Korhonen;Tuija Mustonen;Victor W. M. van Hinsbergh

  • Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins.

    Marika J Karkkainen;Paula Haiko;Kirsi Sainio;Juha Partanen

  • Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

    Michael Jeltsch;Arja Kaipainen;Arja Kaipainen;Vladimir Joukov;Vladimir Joukov;Xiaojuan Meng;Xiaojuan Meng

  • Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

    Marc G. Achen;Michael Jeltsch;Eola Kukk;Taija Mäkinen

  • Clinical applications of angiogenic growth factors and their inhibitors.

    Napoleone Ferrara;Kari Alitalo

  • Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system

    Hellmut G. Augustin;Gou Young Koh;Gavin Thurston;Kari Alitalo

  • Lymphangiogenesis in development and human disease

    Kari Alitalo;Kari Alitalo;Tuomas Tammela;Tuomas Tammela;Tatiana V. Petrova;Tatiana V. Petrova

  • Lymphangiogenesis: Molecular Mechanisms and Future Promise

    Tuomas Tammela;Kari Alitalo

  • Vascular endothelial growth factor‐C‐mediated lymphangiogenesis promotes tumour metastasis

    Stefano J. Mandriota;Lotta Jussila;Michael Jeltsch;Amelia Compagni

  • Angiosarcomas Express Mixed Endothelial Phenotypes of Blood and Lymphatic Capillaries: Podoplanin as a Specific Marker for Lymphatic Endothelium

    Silvana Breiteneder-Geleff;Afschin Soleiman;Heinrich Kowalski;Reinhard Horvat

  • The lymphatic vasculature in disease

    Kari Alitalo

  • The biology of vascular endothelial growth factors

    Tuomas Tammela;Berndt Enholm;Kari Alitalo;Karri Paavonen

  • Cardiovascular Failure in Mouse Embryos Deficient in VEGF Receptor-3

    Daniel J. Dumont;Lotta Jussila;Jussi Taipale;Athina Lymboussaki

  • A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases (vol 15, pg 290, 1996)

    V Joukov;K Pajusola;A Kaipainen;D Chilov

Frequent Co-Authors

Seppo Ylä-Herttuala
Seppo Ylä-Herttuala University of Eastern Finland
Marc G. Achen
Marc G. Achen St Vincents Institute of Medical Research
Tuomas Tammela
Tuomas Tammela Memorial Sloan Kettering Cancer Center
Taija Makinen
Taija Makinen Jenny ja Antti Wihurin Rahasto
Steven A. Stacker
Steven A. Stacker Peter MacCallum Cancer Centre
Tomi P. Mäkelä
Tomi P. Mäkelä University of Helsinki
Tatiana V. Petrova
Tatiana V. Petrova University of Lausanne
Juha Partanen
Juha Partanen University of Helsinki
Ulf Eriksson
Ulf Eriksson AstraZeneca (United Kingdom)
Antti Vaheri
Antti Vaheri University of Helsinki

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