D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge
Medicine
Finland
2022

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 171 Citations 109,310 503 World Ranking 176 National Ranking 2
Best Scientists D-index 202 Citations 153,457 879 World Ranking 169 National Ranking 3

Research.com Recognitions

Awards & Achievements

2022 - Research.com Best Scientist Award

2022 - Research.com Medicine in Finland Leader Award

2013 - Member of the National Academy of Sciences

2011 - Member of Academia Europaea

Member of the European Molecular Biology Organization (EMBO)

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Cancer
  • Internal medicine

The scientist’s investigation covers issues in Angiogenesis, Lymphatic system, Vascular endothelial growth factor C, Vascular endothelial growth factor and Pathology. Her Angiogenesis research incorporates themes from Endothelial stem cell, Endothelium, Receptor tyrosine kinase and Cell biology. The concepts of her Lymphatic system study are interwoven with issues in Lymph and Lymph sacs, Lymphatic vessel, Lymphangiogenesis.

Her research investigates the link between Lymphangiogenesis and topics such as Immunology that cross with problems in Lymphedema. Her Vascular endothelial growth factor research is multidisciplinary, incorporating perspectives in Endocrinology and Growth factor. The various areas that Kari Alitalo examines in her Pathology study include Tumor progression and Circulatory system.

Her most cited work include:

  • VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia (2179 citations)
  • A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. (1612 citations)
  • Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis (1448 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of investigation include Angiogenesis, Cell biology, Cancer research, Lymphatic system and Vascular endothelial growth factor C. Her studies deal with areas such as Endothelial stem cell, Vascular endothelial growth factor, Immunology, Receptor tyrosine kinase and Endothelium as well as Angiogenesis. Her Cell biology study incorporates themes from Receptor, Angiopoietin receptor and Molecular biology.

Her Cancer research research includes elements of Carcinogenesis, Cancer and Gene. Her biological study deals with issues like Lymphangiogenesis, which deal with fields such as Inflammation. Her Vascular endothelial growth factor C research integrates issues from Kinase insert domain receptor, Vascular endothelial growth factor B, Vascular Endothelial Growth Factor D, Vascular permeability and Vascular endothelial growth inhibitor.

She most often published in these fields:

  • Angiogenesis (29.80%)
  • Cell biology (27.40%)
  • Cancer research (25.44%)

What were the highlights of her more recent work (between 2012-2021)?

  • Lymphatic system (23.25%)
  • Lymphangiogenesis (22.05%)
  • Angiogenesis (29.80%)

In recent papers she was focusing on the following fields of study:

Her main research concerns Lymphatic system, Lymphangiogenesis, Angiogenesis, Cell biology and Pathology. The study incorporates disciplines such as Lymph node, Lymphedema, Anatomy and Lymphatic vessel in addition to Lymphatic system. Her studies in Lymphangiogenesis integrate themes in fields like Vascular endothelial growth factor C, Inflammation, Immune system, Immunology and Lacteal.

Her Angiogenesis study combines topics in areas such as Endothelial stem cell and Vascular endothelial growth factor, Angiopoietin. Her work deals with themes such as Regulator and Receptor, Biochemistry, Paracrine signalling, which intersect with Cell biology. Her Pathology study combines topics from a wide range of disciplines, such as Reperfusion injury, Ischemia and Endothelium.

Between 2012 and 2021, her most popular works were:

  • A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules (864 citations)
  • Immune cells control skin lymphatic electrolyte homeostasis and blood pressure (236 citations)
  • Understanding the functions and relationships of the glymphatic system and meningeal lymphatics (209 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Internal medicine

Kari Alitalo mainly investigates Lymphangiogenesis, Cell biology, Lymphatic system, Angiogenesis and Vascular endothelial growth factor C. Her work carried out in the field of Lymphangiogenesis brings together such families of science as Endothelial stem cell, Immunology, Pathogenesis, Progenitor cell and Receptor tyrosine kinase. Her Cell biology research includes themes of Vascular endothelial growth factor A, Endothelium, Autocrine signalling and Paracrine signalling.

To a larger extent, Kari Alitalo studies Pathology with the aim of understanding Lymphatic system. Her research integrates issues of Vascular endothelial growth factor B and Vascular endothelial growth factor, Angiopoietin in her study of Angiogenesis. Her Vascular endothelial growth factor C research integrates issues from Endocrinology, Growth factor, Lymphatic Endothelium and Anatomy.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

Holger Gerhardt;Matthew Golding;Marcus Fruttiger;Christiana Ruhrberg.
Journal of Cell Biology (2003)

2922 Citations

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.

V Joukov;K Pajusola;A Kaipainen;D Chilov.
The EMBO Journal (1996)

2434 Citations

Molecular regulation of angiogenesis and lymphangiogenesis.

Ralf H. Adams;Kari Alitalo.
Nature Reviews Molecular Cell Biology (2007)

2358 Citations

Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis

Mihaela Skobe;Thomas Hawighorst;David G. Jackson;Remko Prevo.
Nature Medicine (2001)

2264 Citations

Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.

Manfred Schwab;Kari Alitalo;Karl Heinz Klempnauer;Harold E. Varmus.
Nature (1983)

1789 Citations

Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development.

Arja Kaipainen;Jaana Korhonen;Tuija Mustonen;Victor W. M. van Hinsbergh.
Proceedings of the National Academy of Sciences of the United States of America (1995)

1692 Citations

Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

Michael Jeltsch;Arja Kaipainen;Vladimir Joukov;Xiaojuan Meng.
Science (1997)

1643 Citations

Clinical applications of angiogenic growth factors and their inhibitors

Napoleone Ferrara;Kari Alitalo.
Nature Medicine (1999)

1642 Citations

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

Marc G. Achen;Michael Jeltsch;Eola Kukk;Taija Mäkinen.
Proceedings of the National Academy of Sciences of the United States of America (1998)

1561 Citations

Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins.

Marika J Karkkainen;Paula Haiko;Kirsi Sainio;Juha Partanen.
Nature Immunology (2004)

1519 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Kari Alitalo

Peter Carmeliet

Peter Carmeliet

KU Leuven

Publications: 188

Seppo Ylä-Herttuala

Seppo Ylä-Herttuala

University of Eastern Finland

Publications: 187

Michael Detmar

Michael Detmar

École Polytechnique Fédérale de Lausanne

Publications: 174

Christer Betsholtz

Christer Betsholtz

Uppsala University

Publications: 139

Napoleone Ferrara

Napoleone Ferrara

University of California, San Diego

Publications: 134

Hellmut G. Augustin

Hellmut G. Augustin

German Cancer Research Center

Publications: 123

Ralf H. Adams

Ralf H. Adams

Max Planck Society

Publications: 102

Yihai Cao

Yihai Cao

Karolinska Institute

Publications: 101

Claus Cursiefen

Claus Cursiefen

University of Cologne

Publications: 100

Holger Gerhardt

Holger Gerhardt

Max Delbrück Center for Molecular Medicine

Publications: 99

Masabumi Shibuya

Masabumi Shibuya

Jobu University

Publications: 98

Anne Eichmann

Anne Eichmann

Yale University

Publications: 97

Domenico Ribatti

Domenico Ribatti

University of Bari Aldo Moro

Publications: 90

Gou Young Koh

Gou Young Koh

Korea Advanced Institute of Science and Technology

Publications: 86

Rakesh K. Jain

Rakesh K. Jain

Harvard University

Publications: 85

Lena Claesson-Welsh

Lena Claesson-Welsh

Uppsala University

Publications: 81

Trending Scientists

Hiroshi Konno

Hiroshi Konno

Chuo University

Suresh Chandra Satapathy

Suresh Chandra Satapathy

KIIT University

Praveen Linga

Praveen Linga

National University of Singapore

Frieder W. Scheller

Frieder W. Scheller

University of Potsdam

Zhihong Liu

Zhihong Liu

Wuhan University

Ajeet Rohatgi

Ajeet Rohatgi

Georgia Institute of Technology

J.B. van Wyk

J.B. van Wyk

University of the Free State

Denise A. Galloway

Denise A. Galloway

Fred Hutchinson Cancer Research Center

Michael A. J. Ferguson

Michael A. J. Ferguson

University of Dundee

Sean Swenson

Sean Swenson

National Center for Atmospheric Research

Roman A. Schmitt

Roman A. Schmitt

Oregon State University

Elie Bou-Zeid

Elie Bou-Zeid

Princeton University

Michael E. Q. Pilson

Michael E. Q. Pilson

University of Rhode Island

Barbara Mullan

Barbara Mullan

Curtin University

Steven D. Brown

Steven D. Brown

Loyola University Chicago

Eszter Hargittai

Eszter Hargittai

University of Zurich

Something went wrong. Please try again later.