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D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
18371
World Ranking
16444
National Ranking
6804

Overview

Tuomas Tammela is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research spans several key areas in biomedical science with a strong emphasis on cancer biology and molecular mechanisms underlying cancer progression.

Their recent publications illustrate diverse interests within cancer research and related fields. Notable papers include:

  • Emergence of a High-Plasticity Cell State during Lung Cancer Evolution, 2020, Cancer Cell
  • Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling, 2020, Science Translational Medicine
  • Exercise and immunometabolic regulation in cancer, 2020, Nature Metabolism
  • Cellular and molecular mechanisms of plasticity in cancer, 2022, Trends in cancer
  • Expression of R-Spondin 1 in Apc Mice Suppresses Growth of Intestinal Adenomas by Altering Wnt and Transforming Growth Factor Beta Signaling, 2020, Gastroenterology

The scientist frequently collaborates with researchers including Zhuxuan Li, Jason E. Chan, Simon Joost, Yan Yan, and Anupriya Singhal, with whom they have multiple joint publications.

Tammela's work appears regularly in established scientific venues. The most common publication venues are:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Cell
  • Cancer Discovery
  • Nature

Their primary fields of study encompass Biochemistry, Genetics and Molecular Biology, and Medicine, with significant contributions in several subfields such as:

  • Molecular Biology
  • Oncology
  • Cancer Research
  • Biomedical Engineering
  • Physiology

Tammela's research topics focus on aspects of cancer biology and diagnostics with special attention to:

  • Cancer Cells and Metastasis
  • Cancer Genomics and Diagnostics
  • RNA modifications and cancer
  • Epigenetics and DNA Methylation
  • Pancreatic and Hepatic Oncology Research
  • Single-cell and spatial transcriptomics
  • Nanoplatforms for cancer theranostics

Best Publications

  • Lymphangiogenesis in development and human disease

    Kari Alitalo;Kari Alitalo;Tuomas Tammela;Tuomas Tammela;Tatiana V. Petrova;Tatiana V. Petrova

  • Lymphangiogenesis: Molecular Mechanisms and Future Promise

    Tuomas Tammela;Kari Alitalo

  • The biology of vascular endothelial growth factors

    Tuomas Tammela;Berndt Enholm;Kari Alitalo;Karri Paavonen

  • Macrophages regulate salt-dependent volume and blood pressure by a vascular endothelial growth factor-C–dependent buffering mechanism

    Agnes Machnik;Wolfgang Neuhofer;Jonathan Jantsch;Anke Dahlmann

  • Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

    Tuomas Tammela;Georgia Zarkada;Elisabet Wallgard;Aino Murtomäki

  • VEGFs and receptors involved in angiogenesis versus lymphangiogenesis.

    Marja Lohela;Maija Bry;Tuomas Tammela;Kari Alitalo

  • CRISPR-mediated direct mutation of cancer genes in the mouse liver

    Wen-Bin Xue;Sidi Chen;Hao Yin;Tuomas Tammela

  • Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation

    Peter Baluk;Tuomas Tammela;Erin Ator;Natalya Lyubynska

  • Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation

    Pipsa Saharinen;Tuomas Tammela;Marika J Karkkainen;Kari Alitalo

  • Rapid modelling of cooperating genetic events in cancer through somatic genome editing

    Francisco J. Sánchez-Rivera;Thales Papagiannakopoulos;Rodrigo Romero;Tuomas Tammela

  • Regulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses

    Nikhil S. Joshi;Elliot H. Akama-Garren;Yisi Lu;Da-Yae Lee

  • Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation

    Tuomas Tammela;Anne Saaristo;Tanja Holopainen;Johannes Lyytikkä

  • In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis

    Jatin Roper;Jatin Roper;Tuomas Tammela;Naniye Malli Cetinbas;Adam Akkad

  • VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling

    Tuomas Tammela;Georgia Zarkada;Harri Nurmi;Lars Jakobsson

  • Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6

    Joo-Hyeon Lee;Tuomas Tammela;Matan Hofree;Jinwook Choi

  • A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma

    Tuomas Tammela;Francisco J. Sanchez-Rivera;Naniye Malli Cetinbas;Katherine Wu

  • Angiopoietin-1 promotes lymphatic sprouting and hyperplasia.

    Tuomas Tammela;Anne Saaristo;Marja Lohela;Tohru Morisada

  • Vascular Endothelial Growth Factor-C Accelerates Diabetic Wound Healing

    Anne Saaristo;Tuomas Tammela;Anniina Fārkkilā;Marika Kärkkäinen

  • Emergence of a High-Plasticity Cell State during Lung Cancer Evolution

    Nemanja Despot Marjanovic;Nemanja Despot Marjanovic;Matan Hofree;Jason E. Chan;David Canner

  • Small RNA combination therapy for lung cancer

    Wen Xue;James E. Dahlman;Tuomas Tammela;Omar F. Khan

Frequent Co-Authors

Kari Alitalo
Kari Alitalo University of Helsinki
Seppo Ylä-Herttuala
Seppo Ylä-Herttuala University of Eastern Finland
Wen Xue
Wen Xue University of Massachusetts Chan Medical School
Roderick T. Bronson
Roderick T. Bronson Harvard University
Tatiana V. Petrova
Tatiana V. Petrova University of Lausanne
Anne Eichmann
Anne Eichmann Yale University
Aviv Regev
Aviv Regev Genentech

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