World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
12516
World Ranking
15497
National Ranking
6469

Overview

Young-Kwon Hong is affiliated with the University of Southern California in the United States. Their research primarily focuses on the field of Medicine, with significant contributions across several subfields including Oncology, Molecular Biology, Physiology, Pulmonary and Respiratory Medicine, and Ophthalmology.

The scientist's research topics encompass various areas, notably:

  • Lymphatic System and Diseases
  • Angiogenesis and VEGF in Cancer
  • Glaucoma and retinal disorders
  • Erythrocyte Function and Pathophysiology
  • Cerebrospinal fluid and hydrocephalus
  • Neonatal Respiratory Health Research
  • Sympathectomy and Hyperhidrosis Treatments

Young-Kwon Hong has published papers in a variety of scientific journals. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Investigation
  • Nature Neuroscience
  • JCI Insight
  • American Journal Of Pathology

Some of the recent publications by the scientist are:

  • Piezo1-Regulated Mechanotransduction Controls Flow-Activated Lymphatic Expansion, 2022, Circulation Research
  • Perfusable micro-vascularized 3D tissue array for high-throughput vascular phenotypic screening, 2022, Nano Convergence
  • Organogenesis and distribution of the ocular lymphatic vessels in the anterior eye, 2020, JCI Insight
  • Ras Pathways on Prox1 and Lymphangiogenesis: Insights for Therapeutics, 2020, Frontiers in Cardiovascular Medicine
  • Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice, 2023, Journal of Clinical Investigation

The scientist has collaborated frequently with several co-authors, including:

  • Dongwon Choi
  • Alex K. Wong
  • Alex S. Huang
  • Eunkyung Park
  • James Yu

Best Publications

  • T1α/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema

    Vivien Schacht;Maria I. Ramirez;Young Kwon Hong;Satoshi Hirakawa

  • Up-Regulation of the Lymphatic Marker Podoplanin, a Mucin-Type Transmembrane Glycoprotein, in Human Squamous Cell Carcinomas and Germ Cell Tumors

    Vivien Schacht;Soheil S. Dadras;Louise A. Johnson;David G. Jackson

  • Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate.

    Young Kwon Hong;Natasha Harvey;Yun Hee Noh;Vivien Schacht

  • Meningeal lymphatic vessels at the skull base drain cerebrospinal fluid

    Ji Hoon Ahn;Hyunsoo Cho;Jun-Hee Kim;Shin Heun Kim

  • Identification of Vascular Lineage-Specific Genes by Transcriptional Profiling of Isolated Blood Vascular and Lymphatic Endothelial Cells

    Satoshi Hirakawa;Young-Kwon Hong;Natasha Harvey;Vivien Schacht

  • Interleukin‐8 is associated with proliferation, migration, angiogenesis and chemosensitivity in vitro and in vivo in colon cancer cell line models

    Yan Ning;Philipp C Manegold;Young Kwon Hong;Wu Zhang

  • Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus.

    Young Kwon Hong;Kimberly Foreman;Jay W. Shin;Satoshi Hirakawa

  • VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the α1β1 and α2β1 integrins

    Young-Kwon Hong;Bernhard Lange-Asschenfeldt;Paula Velasco;Satoshi Hirakawa

  • Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia.

    Rainer Kunstfeld;Satoshi Hirakawa;Young Kwon Hong;Vivien Schacht

  • Intestinal enteroendocrine lineage cells possess homeostatic and injury-inducible stem cell activity

    Kelley S. Yan;Kelley S. Yan;Olivier Gevaert;Grace X.Y. Zheng;Benedict Anchang

  • Visualization of lymphatic vessels by Prox1-promoter directed GFP reporter in a bacterial artificial chromosome-based transgenic mouse

    Inho Choi;Hee Kyoung Chung;Swapnika Ramu;Ha Neul Lee

  • Prox1 Promotes Lineage-specific Expression of Fibroblast Growth Factor (FGF) Receptor-3 in Lymphatic Endothelium: A Role for FGF Signaling in Lymphangiogenesis

    Jay W. Shin;Michael Min;Fréderic Larrieu-Lahargue;Xavier Canron

  • Activation of the Tie2 Receptor by Angiopoietin-1 Enhances Tumor Vessel Maturation and Impairs Squamous Cell Carcinoma Growth

    Thomas Hawighorst;Mihaela Skobe;Michael Streit;Young-Kwon Hong

  • The New Era of the Lymphatic System: No Longer Secondary to the Blood Vascular System

    Inho Choi;Sunju Lee;Young Kwon Hong

  • Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism.

    Thomas Hawighorst;Paula Velasco;Michael Streit;Young‐Kwon Hong

  • Bioleaching of electronic waste using acidophilic sulfur oxidising bacteria

    Y. Hong;M. Valix

  • Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate.

    Sunju Lee;Jinjoo Kang;Jaehyuk Yoo;Sathish Kumar Ganesan

  • Ultraviolet B irradiation of human skin induces an angiogenic switch that is mediated by upregulation of vascular endothelial growth factor and by downregulation of thrombospondin-1.

    Yano K;Kadoya K;Kajiya K;Hong Yk

  • Lymphatic regulator PROX1 determines Schlemm’s canal integrity and identity

    Dae-Young Park;Jun Yeop Lee;In Tae Park;Dongwon Choi

  • A lymphatic defect causes ocular hypertension and glaucoma in mice

    Benjamin R. Thomson;Stefan Heinen;Marie Jeansson;Asish K. Ghosh

Frequent Co-Authors

Michael Detmar
Michael Detmar ETH Zurich
Alexander Wong
Alexander Wong University of Waterloo
Natasha L. Harvey
Natasha L. Harvey University of South Australia
Gou Young Koh
Gou Young Koh Korea Advanced Institute of Science and Technology
Lawrence F. Brown
Lawrence F. Brown Beth Israel Deaconess Medical Center
Jae U. Jung
Jae U. Jung Cleveland Clinic
Guillermo Oliver
Guillermo Oliver Northwestern University
Kari Alitalo
Kari Alitalo University of Helsinki
G. Paolo Dotto
G. Paolo Dotto Harvard University
Heinz-Josef Lenz
Heinz-Josef Lenz University of Southern California

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