Natasha L. Harvey

Overview

Best Publications

• An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype

  Jeffrey T. Wigle;Jeffrey T. Wigle;Natasha Harvey;Michael Detmar;Irina Lagutina

  1149
  Citations

• T1α/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema

  Vivien Schacht;Maria I. Ramirez;Young Kwon Hong;Satoshi Hirakawa

  799
  Citations

• Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate.

  Young Kwon Hong;Natasha Harvey;Yun Hee Noh;Vivien Schacht

  662
  Citations

• The Lymphatic Vasculature in the 21st Century: Novel Functional Roles in Homeostasis and Disease

  Guillermo Oliver;Jonathan Kipnis;Gwendalyn J. Randolph;Natasha L. Harvey

  647
  Citations

• Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity

  Natasha L Harvey;R Sathish Srinivasan;Miriam E Dillard;Nicole C Johnson

  617
  Citations

• Identification of Vascular Lineage-Specific Genes by Transcriptional Profiling of Isolated Blood Vascular and Lymphatic Endothelial Cells

  Satoshi Hirakawa;Young-Kwon Hong;Natasha Harvey;Vivien Schacht

  552
  Citations

• VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells.

  Jackelyn A. Alva;Ann C. Zovein;Arnaud Monvoisin;Thomas Murphy

  497
  Citations

• Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

  Nicole C. Johnson;Miriam E. Dillard;Peter Baluk;Donald M. McDonald

  389
  Citations

• Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature

  Jan Kazenwadel;Genevieve A. Secker;Yajuan J. Liu;Jill A. Rosenfeld

  294
  Citations

• Prodomain-dependent nuclear localization of the caspase-2 (Nedd2) precursor. A novel function for a caspase prodomain.

  Paul A. Colussi;Natasha L. Harvey;Sharad Kumar

  229
  Citations

• Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9.

  L A O'Reilly;P Ekert;N Harvey;V Marsden

  218
  Citations

• GATA2 is required for lymphatic vessel valve development and maintenance

  Jan Kazenwadel;Kelly L. Betterman;Chan-Eng Chong;Philippa H. Stokes

  207
  Citations

• Role of multiple cellular proteases in the execution of programmed cell death.

  Sharad Kumar;Natasha L Harvey

  201
  Citations

• Prox1 expression is negatively regulated by miR-181 in endothelial cells.

  Jan Kazenwadel;Michael Z. Michael;Natasha L. Harvey;Natasha L. Harvey

  183
  Citations

• Functional activation of Nedd2/ICH-1 (caspase-2) is an early process in apoptosis.

  Natasha L. Harvey;Alison J. Butt;Sharad Kumar

  171
  Citations

• Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation.

  Emma J. Gordon;Sujata Rao;Jeffrey W. Pollard;Stephen L. Nutt

  163
  Citations

• Getting out and about: the emergence and morphogenesis of the vertebrate lymphatic vasculature

  Katarzyna Koltowska;Kelly L. Betterman;Natasha L. Harvey;Natasha L. Harvey;Benjamin M. Hogan

  148
  Citations

• The Link between Lymphatic Function and Adipose Biology

  Natasha L. Harvey

  148
  Citations

• Prox1 maintains muscle structure and growth in the developing heart

  Catherine A. Risebro;Richelle G. Searles;Athalie A. D. Melville;Elisabeth Ehler

  146
  Citations

• Dimerization and Autoprocessing of the Nedd2 (Caspase-2) Precursor Requires both the Prodomain and the Carboxyl-terminal Regions

  Alison J. Butt;Natasha L. Harvey;Gayathri Parasivam;Sharad Kumar

  140
  Citations