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D-Index & Metrics

Biology and Biochemistry

D-Index
67
Citations
12559
World Ranking
8386
National Ranking
651

Overview

Elisabeth Ehler is affiliated with King's College London in the United Kingdom. Their research work spans multiple fields primarily within Medicine and Biochemistry, Genetics, and Molecular Biology. Their focus includes cardiology and cardiovascular medicine, molecular biology, surgery, cell biology, and physiology.

The scientist has contributed extensively to topics such as cardiomyopathy and myosin studies, cardiovascular effects of exercise, congenital heart defects research, muscle physiology and disorders, pluripotent stem cells research, tissue engineering and regenerative medicine, and cellular mechanics and interactions.

Frequent co-authors collaborating with Elisabeth Ehler include Friederike Cuello, Janice Raabe, Katja Gehmlich, Angelika Piasecki, and Charlotte Hooper.

Their research is frequently published in venues like Biophysical Reviews, Journal of Biological Chemistry, bioRxiv (Cold Spring Harbor Laboratory), Stem Cell Research, and the Journal of Molecular and Cellular Cardiology.

Selected recent publications by Elisabeth Ehler include:

  • "Electrical stimulation applied during differentiation drives the hiPSC-CMs towards a mature cardiac conduction-like cells", 2020, Biochemical and Biophysical Research Communications
  • "The intercalated disc: a mechanosensing signalling node in cardiomyopathy", 2020, Biophysical Reviews
  • "The titin N2B and N2A regions: biomechanical and metabolic signaling hubs in cross-striated muscles", 2021, Biophysical Reviews
  • "Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant", 2021, Basic Research in Cardiology
  • "Generation of left ventricle-like cardiomyocytes with improved structural, functional, and metabolic maturity from human pluripotent stem cells", 2023, Cell Reports Methods

Best Publications

  • Impaired myocardial angiogenesis and ischemic cardiomyopathy in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188.

    Peter Carmeliet;Yin Shan Ng;Dieter Nuyens;Gregor Theilmeier

  • The Kinase Domain of Titin Controls Muscle Gene Expression and Protein Turnover

    Stephan Lange;Fengqing Xiang;Andrey Yakovenko;Anna Vihola

  • Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly

    Paul Young;Elisabeth Ehler;Mathias Gautel

  • Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2.

    Stephan Lange;Daniel Auerbach;Patricia McLoughlin;Evelyne Perriard

  • Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Cα

    Jürgen Götz;Alphonse Probst;Elisabeth Ehler;Brian Hemmings

  • Myofibrillogenesis in the developing chicken heart: assembly of Z-disk, M-line and the thick filaments.

    E. Ehler;B.M. Rothen;S.P. Hammerle;M. Komiyama

  • Establishment of cardiac cytoarchitecture in the developing mouse heart.

    Alain Hirschy;Franziska Schatzmann;Elisabeth Ehler;Jean-Claude Perriard

  • Dilated cardiomyopathy: a disease of the intercalated disc?

    Jean-Claude Perriard;Alain Hirschy;Elisabeth Ehler

  • WNT-3, expressed by motoneurons, regulates terminal arborization of neurotrophin-3-responsive spinal sensory neurons

    Olga Krylova;Judit Herreros;Karen E Cleverley;Elisabeth Ehler

  • From A to Z and back? Multicompartment proteins in the sarcomere

    Stephan Lange;Elisabeth Ehler;Mathias Gautel

  • Alterations at the intercalated disk associated with the absence of muscle LIM protein.

    Elisabeth Ehler;Robert Horowits;Christian Zuppinger;Robert L. Price

  • Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition.

    Marco Wachtel;Karl Frei;Elisabeth Ehler;Adriano Fontana

  • Sequential myofibrillar breakdown accompanies mitotic division of mammalian cardiomyocytes

    Preeti Ahuja;Evelyne Perriard;Jean-Claude Perriard;Elisabeth Ehler

  • Isolation and Culture of Neonatal Mouse Cardiomyocytes

    Elisabeth Ehler;Thomas Moore-Morris;Stephan Lange

  • Estrogen receptor alpha up-regulation and redistribution in human heart failure

    Shokoufeh Mahmoodzadeh;Sarah Eder;Johannes Nordmeyer;Elisabeth Ehler

  • Beyond the sarcomere: CSRP3 mutations cause hypertrophic cardiomyopathy

    Christian Geier;Katja Gehmlich;Elisabeth Ehler;Sabine Hassfeld

  • Measles virus matrix protein specifies apical virus release and glycoprotein sorting in epithelial cells

    Hussein Y. Naim;Elisabeth Ehler;Martin A. Billeter

  • DRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosis.

    Florence A. Scholl;Patricia McLoughlin;Elisabeth Ehler;Carla de Giovanni

  • Characterisation of postnatal growth of the murine heart.

    Martin Leu;Elisabeth Ehler;J.-C. Perriard

  • Mass Production of Embryoid Bodies in Microbeads

    Josef P. Magyar;Mohamed Nemir;Elisabeth Ehler;Nicolai Suter

Frequent Co-Authors

Cristobal G. dos Remedios
Cristobal G. dos Remedios Victor Chang Cardiac Research Institute
Dieter O. Fürst
Dieter O. Fürst University of Bonn
Mathias Gautel
Mathias Gautel King's College London
Michael P. Sheetz
Michael P. Sheetz The University of Texas Medical Branch at Galveston
Paul R. Riley
Paul R. Riley University of Oxford
William J. McKenna
William J. McKenna University College London
Hugh Watkins
Hugh Watkins University of Oxford
Kenneth R. Chien
Kenneth R. Chien Karolinska Institute
Catherine M. Shanahan
Catherine M. Shanahan King's College London

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