Eric F. Johnson

Overview

Best Publications

• ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor

  Christin Tse;Alexander R. Shoemaker;Jessica Adickes;Mark G. Anderson

  2269
  Citations

• The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature.

  D W Nebert;D R Nelson;M J Coon;R W Estabrook

  1443
  Citations

• The P450 gene superfamily: recommended nomenclature.

  Nebert Dw;Adesnik M;Coon Mj;Estabrook Rw

  1075
  Citations

• The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution.

  Jason K. Yano;Michael R. Wester;Guillaume A. Schoch;Keith J. Griffin

  1009
  Citations

• Mammalian microsomal cytochrome P450 monooxygenase : structural adaptations for membrane binding and functional diversity

  Pamela A. Williams;Jose Cosme;Vandana Sridhar;Eric F. Johnson

  958
  Citations

• ABT-888, an Orally Active Poly(ADP-Ribose) Polymerase Inhibitor that Potentiates DNA-Damaging Agents in Preclinical Tumor Models

  Cherrie K. Donawho;Yan Luo;Yanping Luo;Thomas D. Penning

  885
  Citations

• The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci

  Daniel W. Nebert;David R. Nelson;Milton Adesnik;Minor J. Coon

  854
  Citations

• Peroxisome Proliferator Activated Receptor-α Expression in Human Liver

  Colin N.A. Palmer;Mei H. Hsu;Keith J. Griffin;Judy L. Raucy

  697
  Citations

• Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2.

  Stefaan Sansen;Jason K. Yano;Rosamund L. Reynald;Guillaume A. Schoch

  642
  Citations

• The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0 A Resolution

  Michael R. Wester;Jason K. Yano;Guillaume A. Schoch;Christine Yang

  610
  Citations

• Structure of Human Microsomal Cytochrome P450 2C8 EVIDENCE FOR A PERIPHERAL FATTY ACID BINDING SITE

  Guillaume A. Schoch;Jason K. Yano;Michael R. Wester;Keith J. Griffin

  542
  Citations

• LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P-450 monooxygenase.

  M P Manns;K J Griffin;K F Sullivan;E F Johnson

  529
  Citations

• An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution

  Emily E. Scott;You Ai He;Michael R. Wester;Mark A. White

  441
  Citations

• Structures of Human Microsomal Cytochrome P450 2A6 Complexed With Coumarin And Methoxsalen

  J.K Yano;M.H Hsu;K.J Griffin;C.D Stout

  416
  Citations

• Major antigen of liver kidney microsomal autoantibodies in idiopathic autoimmune hepatitis is cytochrome P450db1.

  M P Manns;E F Johnson;K J Griffin;E M Tan

  413
  Citations

• Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9-A resolution: insight into the range of P450 conformations and the coordination of redox partner binding.

  Emily E. Scott;Mark A. White;You Ai He;Eric F. Johnson

  412
  Citations

• The peroxisome proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid omega-hydroxylase, by clofibric acid.

  A S Muerhoff;K J Griffin;E F Johnson

  401
  Citations

• Novel Sequence Determinants in Peroxisome Proliferator Signaling

  Colin N.A. Palmer;Mei-Hui Hsu;Keith J. Griffin;Eric F. Johnson

  397
  Citations

• Navigating the kinome

  James T Metz;Eric F Johnson;Niru B Soni;Philip J Merta

  381
  Citations

• Discovery of the Poly(ADP-ribose) Polymerase (PARP) Inhibitor 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) for the Treatment of Cancer

  Thomas D Penning;Gui-Dong Zhu;Viraj B Gandhi;Jianchun Gong

  363
  Citations