What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Cytochrome P450, Internal medicine, Endocrinology, Biochemistry and Gene expression.
His Cytochrome P450 study incorporates themes from Phenobarbital, Microsome, Molecular biology and In vivo.
His Internal medicine research focuses on subjects like Phosphorylation, which are linked to Protein inhibitor of activated STAT, stat and STAT4.
The concepts of his Endocrinology study are interwoven with issues in Alpha and Hepatocyte.
His studies in Gene expression integrate themes in fields like Regulation of gene expression, Transcription factor and STAT5B.
His research integrates issues of Monooxygenase and Drug metabolism in his study of Cytochrome.
His most cited work include:
- P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature (2562 citations)
- The P450 Superfamily: Update on New Sequences, Gene Mapping, Accession Numbers, Early Trivial Names of Enzymes, and Nomenclature (1464 citations)
- The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature. (958 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Internal medicine, Endocrinology, Cytochrome P450, Biochemistry and Gene expression.
Internal medicine is closely attributed to Messenger RNA in his study.
His research on Endocrinology often connects related topics like STAT5B.
He has researched Cytochrome P450 in several fields, including Drug metabolism, Prodrug, Pharmacology, Molecular biology and Microsome.
His study explores the link between Microsome and topics such as Hydroxylation that cross with problems in Steroid, Chromatography and Stereochemistry.
His study in Gene expression is interdisciplinary in nature, drawing from both Regulation of gene expression, Transcription factor, STAT5 and STAT5B Gene.
He most often published in these fields:
- Internal medicine (31.68%)
- Endocrinology (31.44%)
- Cytochrome P450 (27.23%)
What were the highlights of his more recent work (between 2012-2021)?
- Chromatin (6.44%)
- Gene (15.10%)
- Gene expression (17.57%)
In recent papers he was focusing on the following fields of study:
David J. Waxman mostly deals with Chromatin, Gene, Gene expression, Internal medicine and Endocrinology.
His Chromatin research incorporates themes from Enhancer, CTCF, Histone and Cell biology.
His Gene study introduces a deeper knowledge of Genetics.
His work in the fields of Regulation of gene expression, Genetic heterogeneity and Allele overlaps with other areas such as Expression quantitative trait loci.
His work deals with themes such as Transcription factor and STAT5, which intersect with Gene expression.
His research in Endocrinology is mostly focused on Hormone.
Between 2012 and 2021, his most popular works were:
- Metronomic chemotherapy: an attractive alternative to maximum tolerated dose therapy that can activate anti-tumor immunity and minimize therapeutic resistance (115 citations)
- Genome-Wide Analysis of Chromatin States Reveals Distinct Mechanisms of Sex-Dependent Gene Regulation in Male and Female Mouse Liver (90 citations)
- Immunogenic chemotherapy: Dose and schedule dependence and combination with immunotherapy. (87 citations)
In his most recent research, the most cited papers focused on:
David J. Waxman mainly investigates Internal medicine, Endocrinology, Chromatin, Transcription factor and Gene.
His studies deal with areas such as FOXM1 and Sensitization as well as Internal medicine.
His work carried out in the field of Endocrinology brings together such families of science as Cancer research, Transcriptome, Gene expression, STAT5B and Nuclear receptor.
The Gene expression study combines topics in areas such as Genetic heterogeneity, Transcription, STAT5 and Cell biology.
His Chromatin research also works with subjects such as
- Promoter together with Cistrome, Binding site, Molecular biology, Enhancer and FOXA2,
- Liver function, Human genome, CTCF and Cohesin most often made with reference to Histone.
As a part of the same scientific family, he mostly works in the field of Transcription factor, focusing on Epigenetics and, on occasion, Growth hormone secretion, Estrogen and Cytochrome P450.
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