His primary areas of investigation include Cytochrome P450, Internal medicine, Endocrinology, Biochemistry and Gene expression. His Cytochrome P450 study incorporates themes from Phenobarbital, Microsome, Molecular biology and In vivo. His Internal medicine research focuses on subjects like Phosphorylation, which are linked to Protein inhibitor of activated STAT, stat and STAT4.
The concepts of his Endocrinology study are interwoven with issues in Alpha and Hepatocyte. His studies in Gene expression integrate themes in fields like Regulation of gene expression, Transcription factor and STAT5B. His research integrates issues of Monooxygenase and Drug metabolism in his study of Cytochrome.
His main research concerns Internal medicine, Endocrinology, Cytochrome P450, Biochemistry and Gene expression. Internal medicine is closely attributed to Messenger RNA in his study. His research on Endocrinology often connects related topics like STAT5B.
He has researched Cytochrome P450 in several fields, including Drug metabolism, Prodrug, Pharmacology, Molecular biology and Microsome. His study explores the link between Microsome and topics such as Hydroxylation that cross with problems in Steroid, Chromatography and Stereochemistry. His study in Gene expression is interdisciplinary in nature, drawing from both Regulation of gene expression, Transcription factor, STAT5 and STAT5B Gene.
David J. Waxman mostly deals with Chromatin, Gene, Gene expression, Internal medicine and Endocrinology. His Chromatin research incorporates themes from Enhancer, CTCF, Histone and Cell biology. His Gene study introduces a deeper knowledge of Genetics.
His work in the fields of Regulation of gene expression, Genetic heterogeneity and Allele overlaps with other areas such as Expression quantitative trait loci. His work deals with themes such as Transcription factor and STAT5, which intersect with Gene expression. His research in Endocrinology is mostly focused on Hormone.
David J. Waxman mainly investigates Internal medicine, Endocrinology, Chromatin, Transcription factor and Gene. His studies deal with areas such as FOXM1 and Sensitization as well as Internal medicine. His work carried out in the field of Endocrinology brings together such families of science as Cancer research, Transcriptome, Gene expression, STAT5B and Nuclear receptor.
The Gene expression study combines topics in areas such as Genetic heterogeneity, Transcription, STAT5 and Cell biology. His Chromatin research also works with subjects such as
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P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
David R. Nelson;Luc Koymans;Tetsuya Kamataki;John J. Stegeman.
The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature.
D R Nelson;T Kamataki;D J Waxman;F P Guengerich.
DNA and Cell Biology (1993)
The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature.
D W Nebert;D R Nelson;M J Coon;R W Estabrook.
DNA and Cell Biology (1991)
Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression
Garry B. Udy;Raewyn P. Towers;Russell G. Snell;Richard J. Wilkins.
Proceedings of the National Academy of Sciences of the United States of America (1997)
Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.
F P Guengerich;M V Martin;P H Beaune;P Kremers.
Journal of Biological Chemistry (1986)
P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.
David J. Waxman.
Archives of Biochemistry and Biophysics (1999)
Penicillin-binding proteins and the mechanism of action of beta-lactam antibiotics.
David J. Waxman;Jack L. Strominger.
Annual Review of Biochemistry (1983)
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.
Wen Xie;Anna Radominska-Pandya;Yanhong Shi;Cynthia M. Simon.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes
D J Waxman;G A Dannan;F P Guengerich.
Phenobarbital induction of cytochrome P-450 gene expression.
D J Waxman;L Azaroff.
Biochemical Journal (1992)
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