His primary areas of investigation include Cancer research, Genetics, Pathology, DNA methylation and Epigenetics. His Cancer research study combines topics from a wide range of disciplines, such as Cell growth, Oncogene, Gene duplication, Gene and Tissue microarray. Juan C. Cigudosa is studying Chromosomal translocation, which is a component of Genetics.
Juan C. Cigudosa has included themes like Oncology, Complex Karyotype, Breakpoint, Internal medicine and Trisomy 8 in his Pathology study. His DNA methylation study combines topics from a wide range of disciplines, such as Carcinogenesis, Virus, Hepatitis B virus and Human virome. His Epigenetics research integrates issues from Histone, X-inactivation, Genotype and CpG site.
Juan C. Cigudosa mainly focuses on Cancer research, Genetics, Molecular biology, Pathology and Chromosomal translocation. His biological study spans a wide range of topics, including Cancer, DNA methylation, Gene expression profiling, Mutation and Immunology. His study in Comparative genomic hybridization, Gene, Karyotype, Chromosome and Leukemia is done as part of Genetics.
His study in Molecular biology is interdisciplinary in nature, drawing from both Gene rearrangement, Cytogenetics, Gene duplication, Fluorescence in situ hybridization and Chromosome instability. His work carried out in the field of Pathology brings together such families of science as Internal medicine and In situ hybridization. His work on Breakpoint as part of general Chromosomal translocation research is frequently linked to Acute lymphocytic leukemia, thereby connecting diverse disciplines of science.
His scientific interests lie mostly in Cancer research, Genetics, Gene, Molecular biology and Mutation. Juan C. Cigudosa interconnects Cancer, Immunology, DNA methylation and Gene expression profiling in the investigation of issues within Cancer research. His Immunology research is multidisciplinary, incorporating elements of Apoptosis, Internal medicine and Oncology.
The various areas that he examines in his DNA methylation study include Myeloproliferative Disorders, Epigenetics, Myelodysplastic syndromes and De novo Myelodysplastic Syndrome. His work deals with themes such as Chromatin, Histone and Erythroid cell, which intersect with Molecular biology. His work in Myeloid leukemia addresses subjects such as Leukemia, which are connected to disciplines such as Myeloid, Pathology and Dasatinib.
Juan C. Cigudosa mostly deals with Genetics, Cancer research, Gene, DNA methylation and Regulation of gene expression. His Cancer research study incorporates themes from Mutation, Cancer, Real-time polymerase chain reaction and DNA repair. His research investigates the connection between Gene and topics such as Immunology that intersect with problems in Karyotype and Multivariate analysis.
His DNA methylation research is multidisciplinary, relying on both Methylation, Apoptosis, Essential thrombocythemia, Gene silencing and Epigenetics. His Epigenetics research incorporates themes from Myeloproliferative Disorders, Differentially methylated regions, Myeloid leukemia, Chronic myelomonocytic leukemia and Myelofibrosis. His Regulation of gene expression study integrates concerns from other disciplines, such as Gene knockdown, Epigenetic Profile, 5-Methylcytosine and Histone, EZH2.
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Epigenetic differences arise during the lifetime of monozygotic twins
Mario F. Fraga;Esteban Ballestar;Maria F. Paz;Santiago Ropero.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Spontaneous human adult stem cell transformation
Daniel Rubio;Javier Garcia-Castro;María C. Martín;Ricardo de la Fuente.
Cancer Research (2005)
Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression
María J. Bueno;Ignacio Pérez de Castro;Marta Gómez de Cedrón;Javier Santos.
Cancer Cell (2008)
Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer
Esteban Ballestar;Maria F. Paz;Laura Valle;Susan Wei.
The EMBO Journal (2003)
Chromosomal and gene amplification in diffuse large B-cell lymphoma
Pulivarthi H. Rao;Jane Houldsworth;Katerina Dyomina;Nasser Z. Parsa.
Blood (1998)
Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia
Junping Wei;Mark Wunderlich;Catherine Fox;Sara Alvarez.
Cancer Cell (2008)
Identification of novel cytogenetic markers with prognostic significance in a series of 968 patients with primary myelodysplastic syndromes
Francesc Solé;Elisa Luño;Carmen Sanzo;Blanca Espinet.
Haematologica (2005)
The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer
Agustin F. Fernandez;Cecilia Rosales;Pilar Lopez-Nieva;Osvaldo Graña.
Genome Research (2008)
Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.
Silvia Espejel;Sonia Franco;Sandra Rodríguez-Perales;Simon D. Bouffler.
The EMBO Journal (2002)
Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.
Cristina Balbás-Martínez;Ana Sagrera;Enrique Carrillo-de-Santa-Pau;Julie Earl.
Nature Genetics (2013)
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