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Genetics

D-Index
65
Citations
19654
World Ranking
2674
National Ranking
37

Overview

Juan C. Cigudosa is affiliated with the Instituto de Salud Carlos III in Spain. Their research activity spans multiple fields primarily within Medicine and Biochemistry, Genetics and Molecular Biology.

Their recent published work includes:

  • Variability in Phelan-McDermid Syndrome in a Cohort of 210 Individuals, 2022, Frontiers in Genetics
  • Personalized Precision Medicine for Health Care Professionals: Development of a Competency Framework, 2023, JMIR Medical Education
  • The second-generation antipsychotic drug aripiprazole modulates the serotonergic system in pancreatic islets and induces beta cell dysfunction in female mice, 2021, Diabetologia
  • Further definition of the proximal 19p13.3 microdeletion/microduplication syndrome and implication of PIAS4 as the major contributor, 2020, Clinical Genetics
  • Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition, 2023, Redox Biology

Their frequent co-authors include:

  • Julián Nevado
  • Jair Tenorio
  • Luis A. Pérez-Jurado
  • Pablo Lapunzina
  • Fernando Martín-Sánchez

Juan C. Cigudosa's work has appeared multiple times in these publication venues:

  • JMIR Medical Education
  • Frontiers in Genetics
  • Diabetologia
  • Clinical Genetics
  • Redox Biology

Their main fields of study are Medicine and Biochemistry, Genetics and Molecular Biology, with notable contributions in related subfields such as Genetics, Molecular Biology, Public Health, Environmental and Occupational Health, Surgery, and Endocrinology, Diabetes and Metabolism.

The core research topics covered in their publications include:

  • Genomic variations and chromosomal abnormalities
  • Congenital heart defects research
  • Chromosomal and Genetic Variations
  • Biomedical and Engineering Education
  • Ethics in Clinical Research
  • Interdisciplinary Research and Collaboration
  • Pancreatic function and diabetes

Best Publications

  • Epigenetic differences arise during the lifetime of monozygotic twins

    Mario F. Fraga;Esteban Ballestar;Maria F. Paz;Santiago Ropero

  • Spontaneous human adult stem cell transformation

    Daniel Rubio;Javier Garcia-Castro;María C. Martín;Ricardo de la Fuente

  • Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression

    María J. Bueno;Ignacio Pérez de Castro;Marta Gómez de Cedrón;Javier Santos

  • Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer

    Esteban Ballestar;Maria F. Paz;Laura Valle;Susan Wei

  • Chromosomal and gene amplification in diffuse large B-cell lymphoma

    Pulivarthi H. Rao;Jane Houldsworth;Katerina Dyomina;Nasser Z. Parsa

  • Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia

    Junping Wei;Mark Wunderlich;Catherine Fox;Sara Alvarez

  • Incidence, characterization and prognostic significance of chromosomal abnormalities in 640 patients with primary myelodysplastic syndromes. Grupo Cooperativo Español de Citogenética Hematológica.

    F Solé;B Espinet;G F Sanz;J Cervera

  • Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.

    Cristina Balbás-Martínez;Ana Sagrera;Enrique Carrillo-de-Santa-Pau;Julie Earl

  • The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer

    Agustin F. Fernandez;Cecilia Rosales;Pilar Lopez-Nieva;Osvaldo Graña

  • Cytogenetic risk stratification in chronic myelomonocytic leukemia

    Esperanza Such;José Cervera;Dolors Costa;Francesc Solé

  • Identification of novel cytogenetic markers with prognostic significance in a series of 968 patients with primary myelodysplastic syndromes

    Francesc Solé;Elisa Luño;Carmen Sanzo;Blanca Espinet

  • Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR–Cas9 system

    R. Torres;M. C. Martin;A. Garcia;Juan C. Cigudosa

  • Genomic and expression profiling identifies the B‐cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma

    Andrea Rinaldi;Ivo Kwee;Monica Taborelli;Cristina Largo

  • Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres.

    Silvia Espejel;Sonia Franco;Sandra Rodríguez-Perales;Simon D. Bouffler

  • Immunohistochemical characteristics defined by tissue microarray of hereditary breast cancer not attributable to BRCA1 or BRCA2 mutations: differences from breast carcinomas arising in BRCA1 and BRCA2 mutation carriers.

    José Palacios;Emiliano Honrado;Ana Osorio;Alicia Cazorla

  • Cytogenetic analysis of 280 patients with multiple myeloma and related disorders: Primary breakpoints and clinical correlations

    María J. Calasanz;Juan C. Cigudosa;María D. Odero;Carmen Ferreira

  • Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers.

    José Palacios;Emiliano Honrado;Ana Osorio;Alicia Cazorla

  • Pitfalls in spontaneous in vitro transformation of human mesenchymal stem cells.

    S Garcia;A Bernad;M C Martín;J C Cigudosa

  • Characterization of nonrandom chromosomal gains and losses in multiple myeloma by comparative genomic hybridization.

    Juan C. Cigudosa;Pulivarthi H. Rao;M. Jose Calasanz;M. Dolores Odero

  • Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomas.

    Juan C. Cigudosa;Nasser Z. Parsa;Diane C. Louie;Daniel A. Filippa

Frequent Co-Authors

María José Calasanz
María José Calasanz University of Navarra
Javier Benitez
Javier Benitez Instituto de Salud Carlos III
Felipe Prosper
Felipe Prosper University of Navarra
Francesc Solé
Francesc Solé Autonomous University of Barcelona
José I. Martín-Subero
José I. Martín-Subero University of Barcelona
Miguel A. Piris
Miguel A. Piris Instituto de Salud Carlos III
Reiner Siebert
Reiner Siebert University of Ulm
Manel Esteller
Manel Esteller Josep Carreras Leukaemia Research Institute
Joaquín Dopazo
Joaquín Dopazo Institute of Biomedicine of Seville
James C. Mulloy
James C. Mulloy Cincinnati Children's Hospital Medical Center

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