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Molecular Biology

D-Index
70
Citations
15786
World Ranking
1432
National Ranking
16

Overview

Pablo Menendez is affiliated with the University of Barcelona in Spain. Their research encompasses a wide array of topics within medicine, biochemistry, genetics, and molecular biology, focusing broadly on molecular biology, oncology, hematology, immunology, and public health. The scientist has contributed extensively to research areas such as CAR-T cell therapy, acute lymphoblastic leukemia, acute myeloid leukemia, immune cell function and interaction, hematopoietic stem cell transplantation, virus-based gene therapy, and CRISPR and genetic engineering.

Their recent publications include notable papers such as:

  • The KMT2A recombinome of acute leukemias in 2023, published in Leukemia
  • In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells, 2020, Nature Communications
  • H3K79me2/3 controls enhancer-promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells, 2020, Leukemia
  • 41BB-based and CD28-based CD123-redirected T-cells ablate human normal hematopoiesis in vivo, 2020, Journal for ImmunoTherapy of Cancer
  • Hyaluronic acid-GPRC5C signalling promotes dormancy in haematopoietic stem cells, 2022, Nature Cell Biology

The scientist frequently collaborates with other researchers in their field, with common coauthors including Clara Bueno, Meritxell Vinyoles, Talía Velasco-Hernández, Paolo Petazzi, and Òscar Molina.

Pablo Menendez's work appears regularly in several publication venues, with a significant number of contributions to Klinische Pädiatrie, Experimental Hematology, Blood, bioRxiv (Cold Spring Harbor Laboratory), and the Journal for ImmunoTherapy of Cancer.

Main fields of study represented in their work are medicine and biochemistry, genetics, and molecular biology. Subfields include molecular biology, oncology, hematology, immunology, and public health, environmental and occupational health, all reflecting the interdisciplinary nature of their research focus.

Their research topics primarily cover:

  • CAR-T cell therapy research
  • Acute Lymphoblastic Leukemia research
  • Acute Myeloid Leukemia Research
  • Immune Cell Function and Interaction
  • Hematopoietic Stem Cell Transplantation
  • Virus-based gene therapy research
  • CRISPR and Genetic Engineering

Best Publications

  • Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells.

    Kristin Chadwick;Lisheng Wang;Li Li;Pablo Menendez

  • IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro

    Sean C. Bendall;Morag H. Stewart;Pablo Menendez;Dustin George

  • The MLL recombinome of acute leukemias in 2017

    C Meyer;T Burmeister;D Gröger;G Tsaur

  • The MLL recombinome of acute leukemias in 2013

    C. Meyer;J. Hofmann;T. Burmeister;D. Gröger

  • Endothelial and Hematopoietic Cell Fate of Human Embryonic Stem Cells Originates from Primitive Endothelium with Hemangioblastic Properties

    Lisheng Wang;Li Li;Farbod Shojaei;Farbod Shojaei;Krysta Levac

  • Human Induced Pluripotent Stem Cells Develop Teratoma More Efficiently and Faster Than Human Embryonic Stem Cells Regardless the Site of Injection

    Ivan Gutierrez‐Aranda;Veronica Ramos‐Mejia;Clara Bueno;Martin Munoz‐Lopez

  • Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression

    Lisheng Wang;Pablo Menendez;Farbod Shojaei;Farbod Shojaei;Li Li

  • Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoter.

    Alicia Barroso-delJesus;Cristina Romero-López;Gema Lucena-Aguilar;Gema Lucena-Aguilar;Gustavo J. Melen

  • Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development

    Lisheng Wang;Li Li;Pablo Menendez;Chantal Cerdan

  • The miR-302-367 cluster as a potential stemness regulator in ESCs

    Alicia Barroso-del Jesus;Gema Lucena-Aguilar;Pablo Menendez

  • Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool.

    J. García-Castro;C. Trigueros;Joaquin Madrenas;J. A. Pérez-Simón

  • Clonal isolation of hESCs reveals heterogeneity within the pluripotent stem cell compartment.

    Morag H Stewart;Morag H Stewart;Marc Bossé;Kristin Chadwick;Pablo Menendez

  • Epigenetic silencing of engineered L1 retrotransposition events in human embryonic carcinoma cells

    Jose L Garcia-Perez;Jose L Garcia-Perez;Maria Morell;Maria Morell;Joshua O Scheys;Deanna A Kulpa

  • Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties?

    Puri Catalina;Rosa Montes;Gertru Ligero;Laura C. Sanchez

  • Bone microenvironment signals in osteosarcoma development

    Arantzazu Alfranca;Lucia Martinez-Cruzado;Juan Tornin;Ander Abarrategi;Ander Abarrategi

  • First BNCT treatment of a skin melanoma in Argentina: dosimetric analysis and clinical outcome

    S.J González;M.R Bonomi;G.A Santa Cruz;H.R Blaumann

  • Consensus Guidance for Banking and Supply of Human Embryonic Stem Cell Lines for Research Purposes

    Peter W. Andrews;Javard Arias-Diaz;Jonathan Auerbach;Manuel Alvarez

  • Modeling sarcomagenesis using multipotent mesenchymal stem cells.

    Rene Rodriguez;Ruth Rubio;Pablo Menendez

  • Engineered LINE-1 retrotransposition in nondividing human neurons.

    Angela Macia;Thomas J. Widmann;Sara R. Heras;Veronica Ayllon

  • Bone marrow mesenchymal stem cells from infants with MLL-AF4+ acute leukemia harbor and express the MLL-AF4 fusion gene

    Pablo Menendez;Purificación Catalina;René Rodríguez;Gustavo J. Melen

Frequent Co-Authors

Mario F. Fraga
Mario F. Fraga University of Oviedo
Agustín F. Fernández
Agustín F. Fernández University of Oviedo
Mickie Bhatia
Mickie Bhatia McMaster University
Rolf Marschalek
Rolf Marschalek Goethe University Frankfurt
Jose L. Garcia-Perez
Jose L. Garcia-Perez University of Granada
Mario Delgado
Mario Delgado Spanish National Research Council
Giovanni Cazzaniga
Giovanni Cazzaniga University of Milano-Bicocca
Alberto Orfao
Alberto Orfao University of Salamanca
Dolors Colomer
Dolors Colomer University of Barcelona
Simon Bailey
Simon Bailey Royal Victoria Infirmary

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