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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
96
Citations
35699
World Ranking
1808
National Ranking
32

Medicine

D-Index
96
Citations
36006
World Ranking
9613
National Ranking
293

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Luc Buée is affiliated with the University of Lille in France and has a substantial body of research focused primarily on neurodegenerative diseases, with a strong emphasis on Alzheimer's disease. Their scholarly contributions span the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology, with significant work also positioned within subfields such as Physiology, Molecular Biology, Neurology, Cellular and Molecular Neuroscience, and Psychiatry and Mental Health.

Their research interests cover a variety of topics including:

  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neuroscience and Neuropharmacology Research
  • Extracellular vesicles in disease
  • Adenosine and Purinergic Signaling
  • Dementia and Cognitive Impairment Research
  • Monoclonal and Polyclonal Antibodies Research

Luc Buée has been published extensively in several key scientific venues. Frequent publication outlets for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Alzheimer s & Dementia
  • Brain
  • Acta Neuropathologica Communications
  • Neurobiology of Disease

Among their notable recent papers are:

  • "Novel Alzheimer risk genes determine the microglia response to amyloid-β but not to TAU pathology," 2020, EMBO Molecular Medicine
  • "Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains," 2020, Acta Neuropathologica
  • "Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer's disease," 2020, Nature Neuroscience
  • "IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer's disease," 2021, Cell Reports
  • "GnRH replacement rescues cognition in Down syndrome," 2022, Science

Collaborations feature prominently in Buée's research output, particularly with the following frequent co-authors:

  • David Blum
  • Sabiha Eddarkaoui
  • Morvane Colin
  • Émilie Faivre
  • Séverine Bégard

Best Publications

  • Tau protein isoforms, phosphorylation and role in neurodegenerative disorders

    Luc Buée;Thierry Bussière;Valérie Buée-Scherrer;André Delacourte

  • Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1

    Karen Duff;Karen Duff;Chris Eckman;Cindy Zehr;Cindy Zehr;Xin Yu

  • NLRP3 inflammasome activation drives tau pathology

    Christina Ising;Carmen Venegas;Shuangshuang Zhang;Hannah Scheiblich

  • The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer’s disease

    A. Delacourte;J.P. David;N. Sergeant;L. Buée

  • Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies.

    Goran Šimić;Mirjana Babić Leko;Selina Wray;Charles Harrington

  • Elevated circulating tumor necrosis factor levels in Alzheimer's disease.

    Howard Fillit;Wanhong Ding;Luc Buee;Jill Kalman

  • Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

    J Chapuis;F Hansmannel;M Gistelinck;A Mounier

  • Nuclear Tau, a Key Player in Neuronal DNA Protection

    Audrey Sultan;Fabrice Nesslany;Marie Violet;Séverine Bégard

  • Neurotrophic factors in Alzheimer's disease: role of axonal transport.

    K. Schindowski;K. Belarbi;K. Belarbi;L. Buée;L. Buée

  • Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

    Katharina Schindowski;Katharina Schindowski;Alexis Bretteville;Alexis Bretteville;Karelle Leroy;Séverine Bégard;Séverine Bégard

  • Comparative Biochemistry of Tau in Progressive Supranuclear Palsy, Corticobasal Degeneration, FTDP-17 and Pick's Disease

    Luc Buée;André Delacourte

  • EVpedia: a community web portal for extracellular vesicles research

    Dae-Kyum Kim;Jaewook Lee;Sae Rom Kim;Dong Sic Choi

  • Pathological alterations of the cerebral microvasculature in Alzheimer's disease and related dementing disorders.

    L. Buée;P. R. Hof;C. Bouras;C. Bouras;A. Delacourte;A. Delacourte

  • Tau protein as a differential biomarker of tauopathies.

    Nicolas Sergeant;André Delacourte;Luc Buée

  • Genetic ablation of Dicer in adult forebrain neurons results in abnormal tau hyperphosphorylation and neurodegeneration

    Sébastien S. Hébert;Sébastien S. Hébert;Aikaterini S. Papadopoulou;Pascal Smith;Marie-Christine Galas;Marie-Christine Galas

  • Biochemistry of Tau in Alzheimer’s disease and related neurological disorders

    Nicolas Sergeant;Alexis Bretteville;Malika Hamdane;Marie-Laure Caillet-Boudin

  • Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?

    Cyril Laurent;Luc Buée;David Blum;David Blum

  • PART is part of Alzheimer disease.

    Charles Duyckaerts;Heiko Braak;Jean Pierre Brion;Luc Buée

  • What is the evidence that tau pathology spreads through prion-like propagation?

    Amrit Mudher;Morvane Colin;Simon Dujardin;Miguel Medina

  • EVpedia: A community web portal for extracellular vesicles research

    D.-K. Kim;J. Lee;S. R. Kim;D.-S. Choi

Frequent Co-Authors

David Blum
David Blum University of Lille
André Delacourte
André Delacourte University of Lille
Florence Pasquier
Florence Pasquier University of Lille
Isabelle Landrieu
Isabelle Landrieu University of Lille
Patrick R. Hof
Patrick R. Hof Icahn School of Medicine at Mount Sinai
Guy Lippens
Guy Lippens Federal University of Toulouse Midi-Pyrénées
Rudi D'Hooge
Rudi D'Hooge KU Leuven

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