D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 54 Citations 10,706 166 World Ranking 1916 National Ranking 25

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Neuroscience

Rudi D'Hooge mostly deals with Neuroscience, Knockout mouse, Hippocampus, Morris water navigation task and Alzheimer's disease. The various areas that Rudi D'Hooge examines in his Neuroscience study include Synaptic plasticity, Long-term potentiation, Glutamate receptor and Transgene. Rudi D'Hooge has researched Knockout mouse in several fields, including Differential display, Fragile X syndrome, FMR1 and Gene expression profiling.

His research in Hippocampus intersects with topics in Memoria, Neurocognitive, Nerve net and Behavioral neuroscience. His research integrates issues of Gene dosage and CHL1 in his study of Morris water navigation task. The various areas that Rudi D'Hooge examines in his Alzheimer's disease study include Biochemistry, Immunology, Apolipoproteins E and Amyloid.

His most cited work include:

  • Applications of the Morris water maze in the study of learning and memory. (1508 citations)
  • Fmr1 knockout mice: A model to study fragile X mental retardation (883 citations)
  • Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling (584 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Neuroscience, Internal medicine, Endocrinology, Hippocampus and Morris water navigation task. His Neuroscience research is multidisciplinary, relying on both Synaptic plasticity and Long-term potentiation. His studies in Internal medicine integrate themes in fields like Metachromatic leukodystrophy and Arylsulfatase A.

His Metachromatic leukodystrophy study frequently draws connections to adjacent fields such as Enzyme replacement therapy. Much of his study explores Endocrinology relationship to Alzheimer's disease. Morris water navigation task is a subfield of Cognition that Rudi D'Hooge investigates.

He most often published in these fields:

  • Neuroscience (41.69%)
  • Internal medicine (19.07%)
  • Endocrinology (17.71%)

What were the highlights of his more recent work (between 2014-2021)?

  • Neuroscience (41.69%)
  • Hippocampus (13.35%)
  • Cognition (7.36%)

In recent papers he was focusing on the following fields of study:

Rudi D'Hooge mainly investigates Neuroscience, Hippocampus, Cognition, Morris water navigation task and Internal medicine. The study incorporates disciplines such as Synaptic plasticity, Long-term potentiation and Neurotransmission in addition to Neuroscience. He interconnects Open field, Motor coordination, Spatial memory, Neurocognitive and Novelty in the investigation of issues within Hippocampus.

His research in Morris water navigation task intersects with topics in Striatum, Audiology, Spatial learning, NMDA receptor and Cognitive flexibility. Internal medicine and Endocrinology are frequently intertwined in his study. Rudi D'Hooge focuses mostly in the field of Endocrinology, narrowing it down to matters related to Alzheimer's disease and, in some cases, Gene knockin and Amyloid.

Between 2014 and 2021, his most popular works were:

  • A2A adenosine receptor deletion is protective in a mouse model of Tauopathy. (102 citations)
  • Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors (55 citations)
  • Amyloid-β pathology is attenuated by tauroursodeoxycholic acid treatment in APP/PS1 mice after disease onset (51 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Neuroscience

His primary scientific interests are in Neuroscience, Hippocampal formation, Hippocampus, Long-term potentiation and Internal medicine. The concepts of his Neuroscience study are interwoven with issues in Synaptic plasticity, Genetically modified mouse and Cell biology. As part of the same scientific family, he usually focuses on Cell biology, concentrating on Cerebellum and intersecting with Central nervous system.

His Hippocampal formation research incorporates elements of Alzheimer's disease and Receptor. His Hippocampus study integrates concerns from other disciplines, such as Pathogenesis, Astrogliosis, Ataxia, Motor coordination and Neuropathology. GSK-3 is closely connected to Endocrinology in his research, which is encompassed under the umbrella topic of Internal medicine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Applications of the Morris water maze in the study of learning and memory.

Rudi D’Hooge;Peter P De Deyn.
Brain Research Reviews (2001)

2228 Citations

Fmr1 knockout mice: A model to study fragile X mental retardation

Cathy E. Bakker;Coleta Verheij;Rob Willemsen.
Cell (1994)

883 Citations

Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling

Sara Cipolat;Tomasz Rudka;Dieter Hartmann;Veronica Costa.
Cell (2006)

752 Citations

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio.

Inna Kuperstein;Kerensa Broersen;Kerensa Broersen;Iryna Benilova;Iryna Benilova;Iryna Benilova;Jef Rozenski.
The EMBO Journal (2010)

507 Citations

Phenotypic and Biochemical Analyses of BACE1- and BACE2-deficient Mice

Diana Dominguez;Jos Tournoy;Dieter Hartmann;Tobias Huth.
Journal of Biological Chemistry (2005)

391 Citations

Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice

Ivo Cristiano Martins;Inna Kuperstein;Hannah Wilkinson;Elke Maes.
The EMBO Journal (2008)

355 Citations

Age-dependent cognitive decline in the APP23 model precedes amyloid deposition.

Debby Van Dam;Rudi D'Hooge;Matthias Staufenbiel;Chris Van Ginneken.
European Journal of Neuroscience (2003)

290 Citations

Array-Based Gene Discovery with Three Unrelated Subjects Shows SCARB2/LIMP-2 Deficiency Causes Myoclonus Epilepsy and Glomerulosclerosis

Samuel F Berkovic;Samuel F Berkovic;Leanne M Dibbens;Leanne M Dibbens;Alicia Oshlack;Jeremy D Silver;Jeremy D Silver.
American Journal of Human Genetics (2008)

272 Citations

Tau-Induced Defects in Synaptic Plasticity, Learning, and Memory Are Reversible in Transgenic Mice after Switching Off the Toxic Tau Mutant

Astrid Sydow;Anneke Van der Jeugd;Fang Zheng;Tariq Ahmed.
The Journal of Neuroscience (2011)

270 Citations

L1 Knockout Mice Show Dilated Ventricles, Vermis Hypoplasia and Impaired Exploration Patterns

Erik Fransen;Rudi D'Hooge;Guy Van Camp;Marleen Verhoye.
Human Molecular Genetics (1998)

267 Citations

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