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Genetics

D-Index
88
Citations
25212
World Ranking
1180
National Ranking
43

Overview

Rob Willemsen is affiliated with Erasmus University Rotterdam in the Netherlands. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with a strong focus on medicine. Their scholarly work shows concentration in genetics and molecular biology, alongside contributions in radiology, nuclear medicine and imaging, cell biology, and epidemiology.

The scientist has addressed several topics in their research, including:

  • Genetics and neurodevelopmental disorders
  • Neurogenetic and muscular disorders research
  • Corneal surgery and disorders
  • Ophthalmology and visual impairment studies
  • Endoplasmic reticulum stress and disease
  • Amyotrophic lateral sclerosis research
  • Autism spectrum disorder research

Rob Willemsen's publication record includes papers in multiple venues, reflecting a diverse interest in both molecular and clinical research. Frequent publication venues include:

  • Disease Models & Mechanisms
  • Frontiers in Molecular Biosciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the American Society of Nephrology
  • Communications Biology

Some recent papers authored or co-authored by Rob Willemsen are:

  • "Comparing Approaches to Normalize, Quantify, and Characterize Urinary Extracellular Vesicles," 2021, Journal of the American Society of Nephrology
  • "Loss of Gap Junction Delta-2 (GJD2) gene orthologs leads to refractive error in zebrafish," 2021, Communications Biology
  • "Mouse models of fragile X-related disorders," 2023, Disease Models & Mechanisms
  • "AMFR dysfunction causes autosomal recessive spastic paraplegia in human that is amenable to statin treatment in a preclinical model," 2023, Acta Neuropathologica
  • "Inducible expression of human C9ORF72 36× G4C2 hexanucleotide repeats is sufficient to cause RAN translation and rapid muscular atrophy in mice," 2021, Disease Models & Mechanisms

Frequent co-authors in Willemsen's network include:

  • Renate K. Hukema
  • Esmay C. van der Toorn
  • Wim H. Quint
  • Magda A. Meester-Smoor
  • Caroline C. W. Klaver

Best Publications

  • Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture–on-chip (4C)

    Marieke Simonis;Petra Klous;Erik Splinter;Yuri Moshkin

  • Fmr1 knockout mice: A model to study fragile X mental retardation

    Cathy E. Bakker;Coleta Verheij;Rob Willemsen

  • Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis

    Ingrid M B H van de Laar;Rogier A Oldenburg;Gerard Pals;Jolien W Roos-Hesselink

  • Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells

    Vedashree Ramakrishnaiah;Christine Thumann;Isabel Fofana;Francois Habersetzer

  • Proteomic Analysis of Exosomes Isolated from Human Malignant Pleural Effusions

    Martin P. Bard;Joost P. Hegmans;Annabrita Hemmes;Theo M. Luider

  • Deletion of FMR1 in Purkinje Cells Enhances Parallel Fiber LTD, Enlarges Spines, and Attenuates Cerebellar Eyelid Conditioning in Fragile X Syndrome

    S.K.E. Koekkoek;K. Yamaguchi;B.A. Milojkovic;B.R. Dortland

  • Characterization and localization of the FMR-1 gene product associated with fragile X syndrome

    C. Verheij;C. E. Bakker;E. De Graaff;J. Keulemans

  • Mutations in SLC30A10 Cause Parkinsonism and Dystonia with Hypermanganesemia, Polycythemia, and Chronic Liver Disease

    Marialuisa Quadri;Antonio Federico;Tianna Zhao;Guido J. Breedveld

  • Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients

    Chantal Sellier;Frédérique Rau;Yilei Liu;Flora Tassone

  • FMRP expression as a potential prognostic indicator in fragile X syndrome.

    Flora Tassone;Randi J. Hagerman;Randi J. Hagerman;David N. Iklé;Pamela N. Dyer

  • Mammalian Golgi‐associated Bicaudal‐D2 functions in the dynein–dynactin pathway by interacting with these complexes

    Casper C. Hoogenraad;Anna Akhmanova;Steven A. Howell;Bjorn R. Dortland

  • Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice.

    Femke M.S. de Vrij;Josien Levenga;Herma C. van der Linde;Sebastiaan K. Koekkoek

  • Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene.

    V. L. J. Tybulewicz;V. L. J. Tybulewicz;M. L. Tremblay;M. L. Tremblay;LaMarca;R. Willemsen

  • The clinical and pathological phenotype of C9ORF72 hexanucleotide repeat expansions

    Javier Simón-Sánchez;Elise G. P. Dopper;Elise G. P. Dopper;Petra E. Cohn-Hokke;Renate K. Hukema

  • The generation of a conditional Fmr1 knock out mouse model to study Fmrp function in vivo.

    E.J. Mientjes;I. Nieuwenhuizen;L. Kirkpatrick;T. Zu

  • L1 Knockout Mice Show Dilated Ventricles, Vermis Hypoplasia and Impaired Exploration Patterns

    Erik Fransen;Rudi D'Hooge;Guy Van Camp;Marleen Verhoye

  • Characterization and localization of the Huntington disease gene product

    André T. Hoogeveen;Rob Willemsen;Nicolle Meyer;Karien E.de Roolj

  • The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome

    Rob Willemsen;Marianne Hoogeveen-Westerveld;Surya Reis;Joan Holstege

  • Differential Expression of FMR1, FXR1 and FXR2 Proteins in Human Brain and Testis

    Filippo Tamanini;Rob Willemsen;Leontine van Unen;Carola Bontekoe

  • Sequestration of DROSHA and DGCR8 by Expanded CGG RNA Repeats Alters MicroRNA Processing in Fragile X-Associated Tremor/Ataxia Syndrome

    Chantal Sellier;Fernande Freyermuth;Ricardos Tabet;Tuan Tran

Frequent Co-Authors

Ben A. Oostra
Ben A. Oostra Erasmus University Rotterdam
Robert F. Berman
Robert F. Berman University of California, Davis
Johan M. Kros
Johan M. Kros Erasmus University Rotterdam
John C. van Swieten
John C. van Swieten Erasmus University Rotterdam
Flora Tassone
Flora Tassone University of California, Davis
Michael R. Hunsaker
Michael R. Hunsaker University of California, Davis
Hans Galjaard
Hans Galjaard Erasmus University Rotterdam
Paul J. Hagerman
Paul J. Hagerman University of California, Davis
David L. Nelson
David L. Nelson Baylor College of Medicine
R. Frank Kooy
R. Frank Kooy University of Antwerp

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