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Overview

Johan M. Kros is affiliated with Erasmus University Rotterdam in the Netherlands. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable focus areas in Genetics, Molecular Biology, Pulmonary and Respiratory Medicine, Cancer Research, and Radiology, Nuclear Medicine and Imaging.

The scientist has contributed extensively to key topics including Glioma Diagnosis and Treatment, Brain Metastases and Treatment, Epigenetics and DNA Methylation, Meningioma and Schwannoma Management, Ferroptosis and Cancer Prognosis, Radiomics and Machine Learning in Medical Imaging, and Cancer Genomics and Diagnostics.

Johan M. Kros has published numerous papers, with recent works including:

  • "cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas" (2020, Acta Neuropathologica)
  • "Adjuvant and concurrent temozolomide for 1p/19q non-co-deleted anaplastic glioma (CATNON; EORTC study 26053-22054): second interim analysis of a randomised, open-label, phase 3 study" (2021, The Lancet Oncology)
  • "Failure of human rhombic lip differentiation underlies medulloblastoma formation" (2022, Nature)
  • "Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy" (2022, Annals of Oncology)
  • "The transcriptional landscape of Shh medulloblastoma" (2021, Nature Communications)

Frequent publication venues for their work include Neuro-Oncology, Acta Neuropathologica, Cancers, Neuro-Oncology Advances, and Clinical Cancer Research.

  • Neuro-Oncology
  • Acta Neuropathologica
  • Cancers
  • Neuro-Oncology Advances
  • Clinical Cancer Research

Johan M. Kros collaborates regularly with several researchers, including Martin J. van den Bent, Pim J. French, Thierry Gorlia, Michael Weller, and Marc Sanson.

  • Martin J. van den Bent
  • Pim J. French
  • Thierry Gorlia
  • Michael Weller
  • Marc Sanson

Best Publications

  • MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma

    Monika E Hegi;Annie-Claire Diserens;Thierry Gorlia;Marie-France Hamou

  • Adjuvant Procarbazine, Lomustine, and Vincristine Chemotherapy in Newly Diagnosed Anaplastic Oligodendroglioma: Long-Term Follow-Up of EORTC Brain Tumor Group Study 26951

    Martin J. van den Bent;Alba A. Brandes;Martin J.B. Taphoorn;Johan M. Kros

  • Intertumoral Heterogeneity within Medulloblastoma Subgroups

    Florence M.G. Cavalli;Marc Remke;Marc Remke;Marc Remke;Ladislav Rampasek;John Peacock

  • Subgroup-specific structural variation across 1,000 medulloblastoma genomes

    Paul A. Northcott;Paul A. Northcott;David J.H. Shih;John Peacock;Livia Garzia

  • Adjuvant Procarbazine, Lomustine, and Vincristine Improves Progression-Free Survival but Not Overall Survival in Newly Diagnosed Anaplastic Oligodendrogliomas and Oligoastrocytomas: A Randomized European Organisation for Research and Treatment of Cancer Phase III Trial

    Martin J. van den Bent;Antoine F. Carpentier;Alba A. Brandes;Marc Sanson

  • Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology

    Lonneke A M Gravendeel;Mathilde C M Kouwenhoven;Olivier Gevaert;Johan J de Rooi

  • Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis

    Ingrid M B H van de Laar;Rogier A Oldenburg;Gerard Pals;Jolien W Roos-Hesselink

  • International Society of Neuropathology-Haarlem Consensus Guidelines for Nervous System Tumor Classification and Grading

    David N. Louis;Arie Perry;Peter Burger;David W. Ellison

  • Randomized Phase II Trial of Erlotinib Versus Temozolomide or Carmustine in Recurrent Glioblastoma: EORTC Brain Tumor Group Study 26034

    Martin J. van den Bent;Alba A. Brandes;Roy Rampling;Mathilde C.M. Kouwenhoven

  • Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study

    Brigitta G Baumert;Brigitta G Baumert;Monika E Hegi;Martin J van den Bent;Andreas von Deimling

  • Diagnosis and treatment of brain metastases from solid tumors: guidelines from the European Association of Neuro-Oncology (EANO).

    Riccardo Soffietti;Ufuk Abacioglu;Brigitta Baumert;Stephanie E Combs

  • cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading.

    David N. Louis;Pieter Wesseling;Kenneth Aldape;Daniel J. Brat

  • cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas.

    Daniel J. Brat;Kenneth Aldape;Howard Colman;Dominique Figrarella-Branger

  • Interim results from the CATNON trial (EORTC study 26053-22054) of treatment with concurrent and adjuvant temozolomide for 1p/19q non-co-deleted anaplastic glioma: a phase 3, randomised, open-label intergroup study

    Martin J van den Bent;Brigitta Baumert;Sara C Erridge;Michael A Vogelbaum;Michael A Vogelbaum

  • Phase II Study of First-Line Chemotherapy With Temozolomide in Recurrent Oligodendroglial Tumors: The European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971

    M J van den Bent;M J B Taphoorn;A A Brandes;Johan Menten

  • Medical applications of Raman spectroscopy: from proof of principle to clinical implementation.

    L.P. Choo-Smith;Howell Edwards;Hubert Endtz;Johan Kros

  • Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis

    Eric M. Thompson;Eric M. Thompson;Thomas Hielscher;Eric Bouffet;Marc Remke

  • IDH1 and IDH2 Mutations Are Prognostic but not Predictive for Outcome in Anaplastic Oligodendroglial Tumors: A Report of the European Organization for Research and Treatment of Cancer Brain Tumor Group

    Martin J. van den Bent;Hendrikus J. Dubbink;Yannick Marie;Alba A. Brandes

  • MGMT Promoter Methylation Is Prognostic but Not Predictive for Outcome to Adjuvant PCV Chemotherapy in Anaplastic Oligodendroglial Tumors: A Report From EORTC Brain Tumor Group Study 26951

    Martin J. van den Bent;Hendrikus J. Dubbink;Marc Sanson;Cathleen R. van der Lee-Haarloo

  • Abstract 808: Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology

    Lonneke Gravendeel;Mathilde Kouwenhoven;Olivier Gevaert;Johan de Rooi

Frequent Co-Authors

Martin J. van den Bent
Martin J. van den Bent Erasmus University Rotterdam
Pieter Wesseling
Pieter Wesseling University of Amsterdam
Alba A. Brandes
Alba A. Brandes Institute of Neurological Sciences
Theo M. Luider
Theo M. Luider Erasmus University Rotterdam
Rob Willemsen
Rob Willemsen Erasmus University Rotterdam
Peter J. van der Spek
Peter J. van der Spek Erasmus University Rotterdam
Michael Weller
Michael Weller University of Zurich
Ahmed Idbaih
Ahmed Idbaih Sorbonne University
Marc Sanson
Marc Sanson Sorbonne University
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center

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