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Medicine

D-Index
88
Citations
57675
World Ranking
12884
National Ranking
178

Overview

Monika E. Hegi is affiliated with the University of Lausanne in Switzerland and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans a variety of subfields, including Genetics, Molecular Biology, Pulmonary and Respiratory Medicine, Neurology, and Radiology, Nuclear Medicine and Imaging.

Their work primarily addresses topics such as Glioma Diagnosis and Treatment, Brain Metastases and Treatment, Radiomics and Machine Learning in Medical Imaging, Immune Cells in Cancer, Neuroinflammation and Neurodegeneration Mechanisms, Single-cell and Spatial Transcriptomics, and Cancer, Hypoxia, and Metabolism.

Among recent notable publications are:

  • EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood, 2020, Nature Reviews Clinical Oncology
  • Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions, 2020, Neuro-Oncology
  • Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells, 2020, Cell
  • The local microenvironment drives activation of neutrophils in human brain tumors, 2023, Cell
  • Compensatory CSF2-driven macrophage activation promotes adaptive resistance to CSF1R inhibition in breast-to-brain metastasis, 2021, Nature Cancer

Their research outputs are frequently published in these venues:

  • Neuro-Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuro-Oncology Advances
  • Nature Reviews Clinical Oncology
  • Cell

Monika E. Hegi has collaborated extensively with several researchers, including Roy Thomas Daniel, Andreas F. Hottinger, Martin J. van den Bent, Pierre Bady, and Michael Weller, with collaboration counts ranging from 11 to 15 publications each.

Best Publications

  • Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

    Roger Stupp;Monika E. Hegi;Warren P. Mason;Martin J. van den Bent

  • MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma

    Monika E Hegi;Annie-Claire Diserens;Thierry Gorlia;Marie-France Hamou

  • Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma: A Randomized Clinical Trial

    Roger Stupp;Roger Stupp;Roger Stupp;Sophie Taillibert;Sophie Taillibert;Andrew Kanner;William Read;William Read

  • Temozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trial

    Annika Malmström;Bjørn Henning Grønberg;Christine Marosi;Roger Stupp

  • Maintenance therapy with tumor-Treating fields plus temozolomide vs temozolomide alone for glioblastoma a randomized clinical trial

    Roger Stupp;Roger Stupp;Sophie Taillibert;Andrew A. Kanner;Santosh Kesari

  • EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood.

    Michael Weller;Martin van den Bent;Matthias Preusser;Emilie Le Rhun

  • Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial

    Roger Stupp;Roger Stupp;Monika E Hegi;Thierry Gorlia;Sara C Erridge

  • Dose-Dense Temozolomide for Newly Diagnosed Glioblastoma: A Randomized Phase III Clinical Trial

    Mark R. Gilbert;Meihua Wang;Kenneth D. Aldape;Roger Stupp

  • Clinical Trial Substantiates the Predictive Value of O-6-Methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastoma Patients Treated with Temozolomide

    Monika E. Hegi;Annie Claire Diserens;Sophie Godard;Pierre Yves Dietrich

  • Correlation of O6-Methylguanine Methyltransferase (MGMT) Promoter Methylation With Clinical Outcomes in Glioblastoma and Clinical Strategies to Modulate MGMT Activity

    Monika E. Hegi;Lili Liu;James G. Herman;Roger Stupp

  • Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma

    Roger Stupp;Roger Stupp;Roger Stupp;Sophie Taillibert;Sophie Taillibert;Andrew Kanner;William Read;William Read

  • European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas

    Michael Weller;Martin van den Bent;Jörg C Tonn;Roger Stupp

  • Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

    Anastasia Murat;Eugenia Migliavacca;Thierry Gorlia;Wanyu L Lambiv

  • MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

    Michael Weller;Roger Stupp;Guido Reifenberger;Alba A. Brandes

  • Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions

    Patrick Y. Wen;Michael Weller;Eudocia Quant Lee;Brian M. Alexander

  • Treatment of brain tumors

    Arnold C. Paulino;Bin S. Teh;Michelle Sadeh;Lynn Ashby

  • Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells

    Florian Klemm;Florian Klemm;Roeltje R. Maas;Robert L. Bowman;Mara Kornete;Mara Kornete

  • Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22.

    Lisa A. Cannon-Albright;David E. Goldgar;Laurence J. Meyer;Cathryn M. Lewis

  • Chemoradiotherapy in malignant glioma: standard of care and future directions.

    Roger Stupp;Monika E. Hegi;Mark R. Gilbert;Arnab Chakravarti

  • In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice.

    M. Harvey;A. T. Sands;R. S. Weiss;M. E. Hegi

Frequent Co-Authors

Roger Stupp
Roger Stupp Northwestern University
Michael Weller
Michael Weller University of Zurich
Wolfgang Wick
Wolfgang Wick German Cancer Research Center
Martin J. van den Bent
Martin J. van den Bent Erasmus University Rotterdam
Mauro Delorenzi
Mauro Delorenzi University of Lausanne
Minesh P. Mehta
Minesh P. Mehta University of Maryland, Baltimore
Mark R. Gilbert
Mark R. Gilbert National Institutes of Health
Alba A. Brandes
Alba A. Brandes Institute of Neurological Sciences
David A. Reardon
David A. Reardon Harvard University
Andreas von Deimling
Andreas von Deimling Heidelberg University

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