World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
90
Citations
48506
World Ranking
11970
National Ranking
163

Overview

Mauro Delorenzi is affiliated with the University of Lausanne in Switzerland. Their research spans various fields, primarily focusing on biochemistry, genetics, molecular biology, medicine, immunology, and microbiology. Delorenzi's work has contributed significantly to multiple subfields, including immunology, molecular biology, cancer research, oncology, and neurology.

Their research investigates topics such as T-cell and B-cell immunology, immune cell function and interaction, cancer-related molecular mechanisms, breast cancer treatment studies, cancer immunotherapy and biomarkers, barrier structure and function studies, and single-cell and spatial transcriptomics.

Delorenzi has published in several prominent venues, which include:

  • Cell Reports
  • Science Advances
  • Cancer Research
  • Neuro-Oncology
  • Nature Communications

Among Delorenzi's recent papers are:

  • 70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age (2021, The Lancet Oncology)
  • Central memory CD8+ T cells derive from stem-like Tcf7hi effector cells in the absence of cytotoxic differentiation (2020, Immunity)
  • Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation (2021, Cancer Cell)
  • Pericytes regulate vascular immune homeostasis in the CNS (2021, Proceedings of the National Academy of Sciences)
  • Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING (2021, Cell Reports)

Delorenzi frequently collaborates with a group of coauthors, including Tania Wyss, David Barras, Martine Piccart, Coralie Poncet, and Fátima Cardoso, with whom they have each published multiple works.

Best Publications

  • The consensus molecular subtypes of colorectal cancer

    Justin Guinney;Rodrigo Dienstmann;Rodrigo Dienstmann;Xingwu Wang;Xingwu Wang;Aurélien De Reyniès

  • Gene Expression Profiling in Breast Cancer: Understanding the Molecular Basis of Histologic Grade To Improve Prognosis

    Christos Sotiriou;Pratyaksha Wirapati;Sherene Loi;Adrian Harris

  • Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

    Wendy De Roock;Bart Claes;David Bernasconi;Jef De Schutter

  • 70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer

    Fatima Cardoso;Laura J. van’t Veer;Jan Bogaerts;Leen Slaets

  • Validation and Clinical Utility of a 70-Gene Prognostic Signature for Women With Node-Negative Breast Cancer

    Marc Buyse;Sherene Loi;Laura van't Veer;Giuseppe Viale

  • The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

    Leming Shi;Gregory Campbell;Wendell D. Jones;Fabien Campagne

  • Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series,

    Christine Desmedt;Fanny Piette;Sherene Loi;Yixin Wang

  • Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

    Antonella Sistigu;Takahiro Yamazaki;Erika Vacchelli;Kariman Chaba

  • A comparison of methods for differential expression analysis of RNA-seq data

    Charlotte Soneson;Mauro Delorenzi;Mauro Delorenzi

  • Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial.

    Arnaud D. Roth;Sabine Tejpar;Mauro Delorenzi;Pu Yan

  • Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures

    Pratyaksha Wirapati;Christos Sotiriou;Susanne Kunkel;Pierre Farmer

  • Identification of molecular apocrine breast tumours by microarray analysis

    Pierre Farmer;Herve Bonnefoi;Véronique Becette;Michele Tubiana-Hulin

  • Definition of Clinically Distinct Molecular Subtypes in Estrogen Receptor–Positive Breast Carcinomas Through Genomic Grade

    Sherene Loi;Benjamin Haibe-Kains;Christine Desmedt;Françoise Lallemand

  • Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes.

    Christine Desmedt;Benjamin Haibe-Kains;Pratyaksha Wirapati;Marc Buyse

  • Regional and cellular gene expression changes in human Huntington's disease brain.

    Angela Kaye Hodges;Andrew D. Strand;Aaron K. Aragaki;Alexandre Kuhn

  • Identification of molecular apocrine breast tumours by microarray analysis

    P Farmer;H Bonnefoi;V Becette;M Tubiana-Hulin

  • TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection.

    Francesca Alfei;Kristiyan Kanev;Maike Hofmann;Ming Wu

  • Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

    Anastasia Murat;Eugenia Migliavacca;Thierry Gorlia;Wanyu L Lambiv

  • A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer

    Pierre Farmer;Pierre Farmer;Pierre Farmer;Hervé Bonnefoi;Pascale Anderle;David Cameron;David Cameron

  • Distal and proximal colon cancers differ in terms of molecular, pathological, and clinical features.

    E. Missiaglia;B. Jacobs;G. D'Ario;A.F. Di Narzo

Frequent Co-Authors

Sabine Tejpar
Sabine Tejpar KU Leuven
Christos Sotiriou
Christos Sotiriou Université Libre de Bruxelles
Monika E. Hegi
Monika E. Hegi University of Lausanne
Fred T. Bosman
Fred T. Bosman University of Lausanne
Roger Stupp
Roger Stupp Northwestern University
Benjamin Haibe-Kains
Benjamin Haibe-Kains Princess Margaret Cancer Centre
Sherene Loi
Sherene Loi Peter MacCallum Cancer Centre
Jonas Bergh
Jonas Bergh Karolinska Institute
Marc Buyse
Marc Buyse Hasselt University

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