World's Best Scientists 2026 revealed!

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Medicine

D-Index
111
Citations
63499
World Ranking
5242
National Ranking
56

Overview

Marc Buyse is affiliated with Hasselt University in Belgium and has contributed extensively to the field of medicine, with a particular focus on oncology and statistical methods applied to clinical trials. Their research portfolio spans multiple dimensions of cancer research, health systems, and economic evaluations in medical treatments.

The main fields of study associated with their work include:

  • Medicine

Subfields with significant representation in their publications are:

  • Oncology
  • Statistics and Probability
  • Pulmonary and Respiratory Medicine
  • Economics and Econometrics
  • Cancer Research

The primary topics researched by Marc Buyse encompass:

  • Statistical Methods in Clinical Trials
  • Health Systems, Economic Evaluations, Quality of Life
  • Colorectal Cancer Treatments and Studies
  • Cancer Genomics and Diagnostics
  • Colorectal Cancer Surgical Treatments
  • Prostate Cancer Treatment and Research
  • Advanced Causal Inference Techniques

Notable recent papers authored or co-authored by Marc Buyse include:

  • International consensus recommendations on key outcome measures for organ preservation after (chemo)radiotherapy in patients with rectal cancer, 2021, Nature Reviews Clinical Oncology
  • FOLFIRI Followed by FOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer: A Randomized GERCOR Study, 2023, Journal of Clinical Oncology
  • Outcome measures in multimodal rectal cancer trials, 2020, The Lancet Oncology
  • Pathologic Complete Response and Individual Patient Prognosis After Neoadjuvant Chemotherapy Plus Anti-Human Epidermal Growth Factor Receptor 2 Therapy of Human Epidermal Growth Factor Receptor 2-Positive Early Breast Cancer, 2023, Journal of Clinical Oncology
  • Surrogacy Beyond Prognosis: The Importance of "Trial-Level" Surrogacy, 2022, The Oncologist

Frequent co-authors collaborating with Marc Buyse include:

  • Everardo D. Saad
  • Tomasz Burzykowski
  • Susan Halabi
  • Nicholas D. James
  • Mickaël De Backer

The scientist has published extensively in several key journals, notably:

  • Journal of Clinical Oncology
  • Annals of Oncology
  • JAMA Oncology
  • Therapeutic Innovation & Regulatory Science
  • Biometrical Journal

Best Publications

  • FOLFIRI Followed by FOLFOX6 or the Reverse Sequence in Advanced Colorectal Cancer: A Randomized GERCOR Study

    Christophe Tournigand;Thierry André;Emmanuel Achille;Gérard Lledo

  • Adjuvant trastuzumab in HER2-positive breast cancer.

    Dennis Slamon;Wolfgang Eiermann;Nicholas Robert;Tadeusz Pienkowski

  • Gene Expression Profiling in Breast Cancer: Understanding the Molecular Basis of Histologic Grade To Improve Prognosis

    Christos Sotiriou;Pratyaksha Wirapati;Sherene Loi;Adrian Harris

  • Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate by the advanced colorectal cancer meta-analysis project

    P. Piedbois;M. Buyse;Y. Rustum;D. Machover

  • Validation and Clinical Utility of a 70-Gene Prognostic Signature for Women With Node-Negative Breast Cancer

    Marc Buyse;Sherene Loi;Laura van't Veer;Giuseppe Viale

  • Efficacy of intravenous continuous infusion of fluorouracil compared with bolus administration in advanced colorectal cancer.

    P Piedbois;P Rougier;M Buyse

  • Long-term results of lung metastasectomy: prognostic analyses based on 5206 cases.

    Ugo Pastorino;Marc Buyse;Godehard Friedel;Robert J. Ginsberg

  • Effects of adjuvant tamoxifen and of cytotoxic therapy on mortality in early breast cancer. An overview of 61 randomized trials among 28,896 women. Early Breast Cancer Trialists' Collaborative Group.

    IC Henderson;H Mouridsen;O Abe;M Abeloff

  • Adjuvant radiotherapy for rectal cancer: a systematic overview of 8,507 patients from 22 randomised trials

    R. Gray;Robert Kerrin Hills;R. Stowe;M. Clarke

  • Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series,

    Christine Desmedt;Fanny Piette;Sherene Loi;Yixin Wang

  • OPTIMOX1: A Randomized Study of FOLFOX4 or FOLFOX7 With Oxaliplatin in a Stop-and-Go Fashion in Advanced Colorectal Cancer—A GERCOR Study

    Christophe Tournigand;Andres Cervantes;Arie Figer;Gérard Lledo

  • Meta-Analysis of Breast Cancer Outcomes in Adjuvant Trials of Aromatase Inhibitors Versus Tamoxifen

    Mitch Dowsett;Jack Cuzick;Jim Ingle;Alan Coates

  • Definition of Clinically Distinct Molecular Subtypes in Estrogen Receptor–Positive Breast Carcinomas Through Genomic Grade

    Sherene Loi;Benjamin Haibe-Kains;Christine Desmedt;Françoise Lallemand

  • Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes.

    Christine Desmedt;Benjamin Haibe-Kains;Pratyaksha Wirapati;Marc Buyse

  • THE EFFECT OF DEBULKING SURGERY AFTER INDUCTION CHEMOTHERAPY ON THE PROGNOSIS IN ADVANCED EPITHELIAL OVARIAN CANCER. GYNECOLOGICAL CANCER COOPERATIVE GROUP OF THE EUROPEAN ORGANIZATION FOR RESEARCH AND TREATMENT OF CANCER

    Maria E.L. van der Burg;Mat van Lent;Marc Buyse;Anna Kobierska

  • Benefit of Adjuvant Chemotherapy for Resectable Gastric Cancer A Meta-analysis

    Gastric (Global Advanced);Xavier Paoletti;Koji Oba

  • Phase III Randomized Trial Comparing Doxorubicin and Cyclophosphamide Followed by Docetaxel (AC→T) with Doxorubicin and Cyclophosphamide Followed by Docetaxel and Trastuzumab (AC→TH) with Docetaxel, Carboplatin and Trastuzumab (TCH) in Her2neu Positive Early Breast Cancer Patients: BCIRG 006 Study.

    D. Slamon;W. Eiermann;N. Robert;T. Pienkowski

  • Preoperative radiotherapy as adjuvant treatment in rectal cancer. Final results of a randomized study of the European Organization for Research and Treatment of Cancer (EORTC).

    André Gerard;Marc Buyse;Bernard Nordlinger;Jean Loygue

  • Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials

    J. Bergh;K. Pritchard;K. Albain;S. Anderson

  • Disease-Free Survival Versus Overall Survival As a Primary End Point for Adjuvant Colon Cancer Studies: Individual Patient Data From 20,898 Patients on 18 Randomized Trials

    Daniel J. Sargent;Harry S. Wieand;Daniel G. Haller;Richard Gray

Frequent Co-Authors

Christos Sotiriou
Christos Sotiriou Université Libre de Bruxelles
Stefan Michiels
Stefan Michiels University of Paris-Saclay
Benjamin Haibe-Kains
Benjamin Haibe-Kains Princess Margaret Cancer Centre
Denis Larsimont
Denis Larsimont Université Libre de Bruxelles
Sherene Loi
Sherene Loi Peter MacCallum Cancer Centre
Mauro Delorenzi
Mauro Delorenzi University of Lausanne
Martine Piccart
Martine Piccart Université Libre de Bruxelles

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