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José A. Salas

José A. Salas

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Biology and Biochemistry
Spain
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
14928
World Ranking
6075
National Ranking
98

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Spain Leader Award

Overview

José A. Salas is affiliated with the University of Oviedo in Spain and is active in research primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans several subfields including Pharmacology, Molecular Biology, Organic Chemistry, Biotechnology, and Infectious Diseases.

The scientific contributions of José A. Salas cover a range of topics, with a significant focus on:

  • Microbial Natural Products and Biosynthesis
  • Genomics and Phylogenetic Studies
  • Synthetic Organic Chemistry Methods
  • Marine Sponges and Natural Products
  • Carbohydrate Chemistry and Synthesis
  • RNA and protein synthesis mechanisms
  • SARS-CoV-2 and COVID-19 Research

Several recent papers from Salas and colleagues illustrate the scope and diversity of their research. Notable publications include:

  • "Efficacy, safety, and immunogenicity of a booster regimen of Ad26.COV2.S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial" (2022), published in The Lancet Infectious Diseases
  • "Identification of Antimicrobial Compounds in Two Streptomyces sp. Strains Isolated From Beehives" (2022), published in Frontiers in Microbiology
  • "Colibrimycins, Novel Halogenated Hybrid Polyketide Synthase-Nonribosomal Peptide Synthetase (PKS-NRPS) Compounds Produced by Streptomyces sp. Strain CS147" (2021), published in Applied and Environmental Microbiology
  • "Discovery of Cryptic Largimycins in Streptomyces Reveals Novel Biosynthetic Avenues Enriching the Structural Diversity of the Leinamycin Family" (2020), published in ACS Chemical Biology
  • "The Volatile Organic Compounds of Streptomyces spp.: An In-Depth Analysis of Their Antifungal Properties" (2023), published in Microorganisms

José A. Salas has collaborated extensively with several frequent co-authors, including:

  • Cármen Méndez
  • Carlos Olano
  • Mónica G. Malmierca
  • Ana Ceniceros
  • Ignacio Pérez-Victoria

Their publications appear often in certain scientific journals, with multiple contributions in:

  • Microorganisms
  • ACS Chemical Biology
  • International Journal of Molecular Sciences
  • Microbial Cell Factories
  • Zenodo (CERN European Organization for Nuclear Research)

Best Publications

  • Minimum Information about a Biosynthetic Gene cluster.

    Marnix H. Medema;Marnix H. Medema;Renzo Kottmann;Pelin Yilmaz;Matthew Cummings

  • Indolocarbazole natural products: occurrence, biosynthesis, and biological activity

    César Sánchez;Carmen Méndez;José A. Salas

  • Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering.

    Carlos Olano;Felipe Lombó;Carmen Méndez;José A. Salas

  • Antitumor Compounds from Marine Actinomycetes

    Carlos Olano;Carmen Méndez;Jose A P Salas

  • Combinatorial biosynthesis of antitumor indolocarbazole compounds

    César Sánchez;Lili Zhu;Alfredo F. Braña;Aaroa P. Salas

  • The Biosynthetic Gene Cluster for the Antitumor Rebeccamycin: Characterization and Generation of Indolocarbazole Derivatives

    César Sánchez;Igor A Butovich;Alfredo F Braña;Jürgen Rohr

  • Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus

    Luis M. Quirós;Ignacio Aguirrezabalaga;Carlos Olano;Carmen Méndez

  • Identification of Two Genes from Streptomyces argillaceus Encoding Glycosyltransferases Involved in Transfer of a Disaccharide during Biosynthesis of the Antitumor Drug Mithramycin

    Ernestina Fernández;Ulrike Weißbach;César Sánchez Reillo;Alfredo F. Braña

  • Altering the glycosylation pattern of bioactive compounds.

    Carmen Méndez;José A Salas

  • Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in two Streptomyces species

    Felipe Lombó;Ana Velasco;Angelina Castro;Fernando de la Calle

  • Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074

    Carlos Olano;Ignacio García;Aranzazu González;Miriam Rodriguez

  • A Regioselective Tryptophan 5-Halogenase Is Involved in Pyrroindomycin Biosynthesis in Streptomyces rugosporus LL-42D005

    Susanne Zehner;Alexander Kotzsch;Bojan Bister;Roderich D. Süssmuth

  • Genes and enzymes involved in deoxysugar biosynthesis in bacteria

    A Trefzer;J A Salas;A Bechthold

  • The aureolic acid family of antitumor compounds: structure, mode of action, biosynthesis, and novel derivatives

    Felipe Lombó;Nuria Menéndez;José A. Salas;Carmen Méndez

  • Engineering the glycosylation of natural products in actinomycetes

    José A. Salas;Carmen Méndez

  • Biosynthesis of the Angiogenesis Inhibitor Borrelidin by Streptomyces parvulus Tü4055: Cluster Analysis and Assignment of Functions

    Carlos Olano;Barrie Wilkinson;César Sánchez;Steven J Moss

  • The role of ABC transporters in antibiotic-producing organisms: drug secretion and resistance mechanisms.

    Carmen Méndez;José A Salas

  • GLUCOKINASE OF RABBIT LIVER.

    José Salas;Margarita Salas;Eladio Viñuela;Alberto Sols

  • Engineering Deoxysugar Biosynthetic Pathways from Antibiotic-Producing Microorganisms: A Tool to Produce Novel Glycosylated Bioactive Compounds

    Leticia Rodrı́guez;Ignacio Aguirrezabalaga;Nerea Allende;Alfredo F Braña

  • Antitumor compounds from actinomycetes: from gene clusters to new derivatives by combinatorial biosynthesis

    Carlos Olano;Carmen Méndez;José A. Salas

Frequent Co-Authors

Carmen Méndez
Carmen Méndez University of Oviedo
Alfredo F. Braña
Alfredo F. Braña University of Oviedo
Jürgen Rohr
Jürgen Rohr University of Kentucky
Andreas Bechthold
Andreas Bechthold University of Freiburg
Peter F. Leadlay
Peter F. Leadlay University of Cambridge
Barrie Wilkinson
Barrie Wilkinson John Innes Centre
Mario Díaz
Mario Díaz University of Oviedo
Fernando Calle
Fernando Calle Technical University of Madrid
Marnix H. Medema
Marnix H. Medema Wageningen University & Research
Nikos C. Kyrpides
Nikos C. Kyrpides Joint Genome Institute

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