His primary areas of study are Biochemistry, Glycorandomization, Glycosylation, Glycosyltransferase and Enzyme. Jon S. Thorson frequently studies issues relating to Enediyne and Biochemistry. His studies deal with areas such as In vitro, Mechanism of action, Combinatorial chemistry, Natural product and Drug discovery as well as Glycorandomization.
The study incorporates disciplines such as Sugar, Small molecule and Cytotoxicity in addition to Glycosylation. His Glycosyltransferase study combines topics in areas such as Glycopeptide, Stereochemistry, Acylation and Nucleotide. His Enzyme study combines topics from a wide range of disciplines, such as Indolocarbazole, Disaccharide, Carbohydrate and Methionine.
Biochemistry, Stereochemistry, Biosynthesis, Enzyme and Glycosylation are his primary areas of study. His study involves Glycosyltransferase, Glycorandomization, Natural product, In vitro and Nucleotide, a branch of Biochemistry. The concepts of his Glycorandomization study are interwoven with issues in Sugar phosphates, Galactokinase and Drug discovery.
His study explores the link between Stereochemistry and topics such as Streptomyces that cross with problems in Cytotoxicity and Metabolite. His study in Biosynthesis is interdisciplinary in nature, drawing from both Indolocarbazole, Gene cluster, Reductase and Enediyne. Glycosylation is closely attributed to Small molecule in his work.
Jon S. Thorson focuses on Stereochemistry, Biochemistry, Biosynthesis, Streptomyces and Cancer research. Jon S. Thorson has researched Stereochemistry in several fields, including Enantioselective synthesis and Regioselectivity. His Biochemistry research focuses on Enzyme, Methionine Adenosyltransferase, Nucleotide, Nucleoside and Glycosylation.
His research investigates the link between Enzyme and topics such as Methyltransferase that cross with problems in Chemical biology and Small molecule. His research in Biosynthesis intersects with topics in Gene cluster, Disaccharide, Reductase and Micromonospora echinospora. His work carried out in the field of Streptomyces brings together such families of science as Amino acid, Isolation, Metabolite, Phenazine and Bacterial strain.
His scientific interests lie mostly in Biochemistry, Medicinal plants, Antibacterial activity, Stereochemistry and Streptomyces. His research related to Biosynthesis, Nucleotide, Enzyme, Nucleoside and Transferase might be considered part of Biochemistry. His work deals with themes such as Disaccharide, Phosphotransferase, Gene cluster and Nucleotidyltransferase, which intersect with Biosynthesis.
In his research, Mutant is intimately related to Methionine Adenosyltransferase, which falls under the overarching field of Enzyme. In his works, Jon S. Thorson performs multidisciplinary study on Stereochemistry and Extramural. His Streptomyces research includes elements of Fatty acid, Aquifex aeolicus, Mutagenesis and Staphylococcus aureus.
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Antitumor antibiotics: bleomycin, enediynes, and mitomycin.
Ute Galm;Martin H. Hager;Steven G. Van Lanen;Jianhua Ju.
Chemical Reviews (2005)
Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells
Mark W. Nowak;Patrick C. Kearney;Jeffrey R. Sampson;Margaret E. Saks.
A genomics-guided approach for discovering and expressing cryptic metabolic pathways.
Emmanuel Zazopoulos;Kexue Huang;Alfredo Staffa;Wen Liu.
Nature Biotechnology (2003)
The calicheamicin gene cluster and its iterative type I enediyne PKS.
Joachim Ahlert;Erica Shepard;Natalia Lomovskaya;Emmanuel Zazopoulos.
Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria.
Hung Wen Liu;Jon S. Thorson.
Annual Review of Microbiology (1994)
Structure, activity, synthesis and biosynthesis of aryl-C-glycosides
Tsion Bililign;Byron R. Griffith;Jon S. Thorson.
Natural Product Reports (2005)
Exploiting the Reversibility of Natural Product Glycosyltransferase-Catalyzed Reactions
Changsheng Zhang;Byron R. Griffith;Qiang Fu;Christoph Albermann.
A comprehensive review of glycosylated bacterial natural products.
Sherif I. Elshahawi;Khaled A. Shaaban;Madan K. Kharel;Jon S. Thorson.
Chemical Society Reviews (2015)
Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization
Joseph M. Langenhan;Noël R. Peters;Ilia A. Guzei;F. Michael Hoffmann.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution
Gavin J Williams;Changsheng Zhang;Jon S Thorson.
Nature Chemical Biology (2007)
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