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Chang-Guo Zhan

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Chemistry 67 6883 6235 2055 1700 396 16357

Chang-Guo Zhan publications per year

The chart shows the history of publications by Chang-Guo Zhan between 1987 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Chang-Guo Zhan published across 39 years, from 1987 to 2025, averaging 11.7 papers a year. Output peaked at 31 publications in 2016. 30 of the 458 publications appeared in the last two years.

No. of publications
10 20 30
Bar chart. Horizontal axis: year, 1987 to 2025. Vertical axis: number of publications, 0 to 31. Peak 31 publications in 2016. 1987: 2 publications 1988: 0 publications 1989: 0 publications 1990: 2 publications 1991: 9 publications 1992: 2 publications 1993: 7 publications 1994: 6 publications 1995: 7 publications 1996: 4 publications 1997: 5 publications 1998: 6 publications 1999: 4 publications 2000: 5 publications 2001: 6 publications 2002: 6 publications 2003: 9 publications 2004: 10 publications 2005: 13 publications 2006: 15 publications 2007: 12 publications 2008: 17 publications 2009: 18 publications 2010: 17 publications 2011: 15 publications 2012: 21 publications 2013: 22 publications 2014: 19 publications 2015: 10 publications 2016: 31 publications 2017: 21 publications 2018: 17 publications 2019: 18 publications 2020: 25 publications 2021: 16 publications 2022: 17 publications 2023: 14 publications 2024: 17 publications 2025: 13 publications
1987 2025

458 publications in total across all disciplines

View publications per year as a table
Chang-Guo Zhan: publications per year, 1987 to 2025
Year Publications
1987 2
1988 0
1989 0
1990 2
1991 9
1992 2
1993 7
1994 6
1995 7
1996 4
1997 5
1998 6
1999 4
2000 5
2001 6
2002 6
2003 9
2004 10
2005 13
2006 15
2007 12
2008 17
2009 18
2010 17
2011 15
2012 21
2013 22
2014 19
2015 10
2016 31
2017 21
2018 17
2019 18
2020 25
2021 16
2022 17
2023 14
2024 17
2025 13
Total 458
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Chang-Guo Zhan publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Chang-Guo Zhan sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 63 bars. Horizontal axis: publications, 61–80 to 1,295+. Vertical axis: number of scientists, 0 to 1,350. Most scientists, 1,350, have 161–180 publications. The last bar groups every scientist with 1,295 publications or more. The highlighted bar, 381–400 publications, is where this scientist sits. 61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61–80 publications 1,295+

This scientist: 396 publications — 80th percentile

80% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

View publications distribution as a table
Number of Chemistry scientists by publication count, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
Publications Scientists This scientist
61–80 66
81–100 302
101–120 623
121–140 918
141–160 1,218
161–180 1,350
181–200 1,344
201–220 1,281
221–240 1,216
241–260 1,100
261–280 979
281–300 939
301–320 764
321–340 643
341–360 628
361–380 522
381–400 459 396
401–420 397
421–440 327
441–460 270
461–480 265
481–500 252
501–520 201
521–540 185
541–560 148
561–580 148
581–600 132
601–620 114
621–640 104
641–660 91
661–680 92
681–700 73
701–720 57
721–740 54
741–760 67
761–780 45
781–800 46
801–820 39
821–840 32
841–860 36
861–880 29
881–900 26
901–920 24
921–940 14
941–960 23
961–980 28
981–1,000 15
1,001–1,020 29
1,021–1,040 12
1,041–1,060 19
1,061–1,080 12
1,081–1,100 6
1,101–1,120 8
1,121–1,140 12
1,141–1,160 5
1,161–1,180 6
1,181–1,200 14
1,201–1,220 7
1,221–1,240 2
1,241–1,260 6
1,261–1,280 4
1,281–1,294 6
1,295+ 100
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Chang-Guo Zhan D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Chang-Guo Zhan sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 61 bars. Horizontal axis: D-Index, 40–41 to 159+. Vertical axis: number of scientists, 0 to 1,051. Most scientists, 1,051, have 56–57 D-Index. The last bar groups every scientist with 159 D-Index or more. The highlighted bar, 66–67 D-Index, is where this scientist sits. 40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40–41 D-Index 159+

This scientist: 67 D-Index — 62nd percentile

62% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

View D-Index distribution as a table
Number of Chemistry scientists by D-index, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
D-Index Scientists This scientist
40–41 289
42–43 612
44–45 808
46–47 776
48–49 835
50–51 861
52–53 872
54–55 933
56–57 1,051
58–59 930
60–61 882
62–63 834
64–65 731
66–67 775 67
68–69 683
70–71 646
72–73 561
74–75 501
76–77 437
78–79 388
80–81 354
82–83 292
84–85 275
86–87 254
88–89 235
90–91 185
92–93 192
94–95 155
96–97 163
98–99 125
100–101 105
102–103 105
104–105 112
106–107 88
108–109 68
110–111 69
112–113 65
114–115 79
116–117 61
118–119 44
120–121 37
122–123 40
124–125 33
126–127 26
128–129 34
130–131 35
132–133 25
134–135 27
136–137 17
138–139 16
140–141 20
142–143 20
144–145 15
146–147 9
148–149 9
150–151 16
152–153 11
154–155 9
156–157 3
158 3
159+ 98
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Overview

Chang-Guo Zhan is affiliated with the University of Kentucky in the United States and has contributed extensively to the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their research intersects multiple subfields including Molecular Biology, Pharmacology, Organic Chemistry, Cellular and Molecular Neuroscience, and Infectious Diseases.

The scientist's work covers a range of topics, predominantly focusing on computational and molecular approaches within biomedical research. Main topics of their research include:

  • Computational Drug Discovery Methods
  • Neurotransmitter Receptor Influence on Behavior
  • Forensic Toxicology and Drug Analysis
  • Receptor Mechanisms and Signaling
  • Cannabis and Cannabinoid Research
  • SARS-CoV-2 and COVID-19 Research
  • HIV Research and Treatment

Chang-Guo Zhan has published in several scientific venues. The most frequent publication venues are:

  • Scientific Reports
  • The Journal of Physical Chemistry B
  • Proceedings of the National Academy of Sciences
  • Neuropharmacology
  • Journal of Medicinal Chemistry

Frequent collaborators include Fang Zheng, Huimei Wei, Alexander H. Williams, Linyue Shang, and Jing Deng, indicating a collaborative research environment across multiple projects.

Significant recent publications by Chang-Guo Zhan include:

  • "Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs," 2020, Proceedings of the National Academy of Sciences
  • "Rational Redesign of Enzyme via the Combination of Quantum Mechanics/Molecular Mechanics, Molecular Dynamics, and Structural Biology Study," 2021, Journal of the American Chemical Society
  • "Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Replenishing HDL with synthetic HDL has multiple protective effects against sepsis in mice," 2022, Science Signaling
  • "Fast Prediction of Binding Affinities of the SARS-CoV-2 Spike Protein Mutant N501Y (UK Variant) with ACE2 and Miniprotein Drug Candidates," 2021, The Journal of Physical Chemistry B

Best Publications

  • Ionization Potential, Electron Affinity, Electronegativity, Hardness, and Electron Excitation Energy: Molecular Properties from Density Functional Theory Orbital Energies

    Chang-Guo Zhan;Jeffrey A. Nichols;David A. Dixon

  • A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

    Tao Zhang;Adel Hamza;Xianhua Cao;Bing Wang

  • Absolute Hydration Free Energy of the Proton from First-Principles Electronic Structure Calculations

    Chang-Guo Zhan;David A. Dixon

  • The tumor inhibitor and antiangiogenic agent withaferin A targets the intermediate filament protein vimentin.

    Paola Bargagna-Mohan;Adel Hamza;Yang-eon Kim;Yik Khuan Abby Ho

  • Withaferin A targets heat shock protein 90 in pancreatic cancer cells.

    Yanke Yu;Adel Hamza;Tao Zhang;Mancang Gu

  • Hydration of the Fluoride Anion: Structures and Absolute Hydration Free Energy from First-Principles Electronic Structure Calculations

    Chang-Guo Zhan;David A. Dixon

  • Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs.

    Zhe Li;Xin Li;Yi You Huang;Yaoxing Wu

  • Most Efficient Cocaine Hydrolase Designed by Virtual Screening of Transition States

    Fang Zheng;Wenchao Yang;Mei Chuan Ko;Junjun Liu

  • Computational redesign of human butyrylcholinesterase for anticocaine medication.

    Yongmei Pan;Daquan Gao;Wenchao Yang;Hoon Cho

  • Electron Affinities of Aln Clusters and Multiple-Fold Aromaticity of the Square Al42- Structure

    Chang-Guo Zhan;Fang Zheng;David A. Dixon

  • VOLUME POLARIZATION IN REACTION FIELD THEORY

    Chang-Guo Zhan;John Bentley;Daniel M. Chipman

  • Fundamental reaction mechanism for cocaine hydrolysis in human butyrylcholinesterase.

    Chang-Guo Zhan;Fang Zheng;Donald W. Landry

  • Fundamental reaction pathway and free energy profile for inhibition of proteasome by Epoxomicin.

    Donghui Wei;Beilei Lei;Mingsheng Tang;Chang-Guo Zhan

  • The Nature and Absolute Hydration Free Energy of the Solvated Electron in Water

    Chang-Guo Zhan;David A. Dixon

  • First-Principles Determination of the Absolute Hydration Free Energy of the Hydroxide Ion†

    Chang-Guo Zhan;David A. Dixon

  • Catalytic mechanism of cytochrome P450 for 5'-hydroxylation of nicotine: fundamental reaction pathways and stereoselectivity.

    Dongmei Li;Xiaoqin Huang;Keli Han;Chang-Guo Zhan

  • Ligand-Based Virtual Screening Approach Using a New Scoring Function

    Adel Hamza;Ning-Ning Wei;Ning-Ning Wei;Chang-Guo Zhan

  • Reaction Pathways and Energy Barriers for Alkaline Hydrolysis of Carboxylic Acid Esters in Water Studied by a Hybrid Supermolecule-Polarizable Continuum Approach

    Chang-Guo Zhan, ,†;and Donald W. Landry;Rick L. Ornstein

  • Cavity size in reaction field theory

    Chang-Guo Zhan;Daniel M. Chipman

  • Modeling the catalysis of anti-cocaine catalytic antibody: competing reaction pathways and free energy barriers.

    Yongmei Pan;Daquan Gao;Chang-Guo Zhan

  • Subnanomolar inhibitor of cytochrome bc1 complex designed by optimizing interaction with conformationally flexible residues.

    Pei-Liang Zhao;Le Wang;Xiao-Lei Zhu;Xiaoqin Huang

Frequent Co-Authors

Guang-Fu Yang
Guang-Fu Yang Central China Normal University
David A. Dixon
David A. Dixon University of Alabama
Hsin-Hsiung Tai
Hsin-Hsiung Tai University of Kentucky
Linda P. Dwoskin
Linda P. Dwoskin University of Kentucky
Jon S. Thorson
Jon S. Thorson University of Kentucky
Peter A. Crooks
Peter A. Crooks University of Arkansas for Medical Sciences
James H. Woods
James H. Woods University of Michigan–Ann Arbor
Stephen Brimijoin
Stephen Brimijoin Mayo Clinic
Ke-Li Han
Ke-Li Han Dalian Institute of Chemical Physics
Vivek M. Rangnekar
Vivek M. Rangnekar University of Kentucky

External Links

Personal website of Chang-Guo Zhan

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Best Scientists Citing Chang-Guo Zhan

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University of Alabama

Publications: 38

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Kazan Federal University

Publications: 37

Stephen Brimijoin

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Mayo Clinic

Publications: 29

Zhen Xi

Zhen Xi

Nankai University

Publications: 18

Jon S. Thorson

Jon S. Thorson

University of Kentucky

Publications: 17

Roger K. Sunahara

Roger K. Sunahara

University of California, San Diego

Publications: 16

Oksana Lockridge

Oksana Lockridge

University of Nebraska Medical Center

Publications: 16

Donald G. Truhlar

Donald G. Truhlar

University of Minnesota

Publications: 15

Florian Nachon

Florian Nachon

Centre national de la recherche scientifique, CNRS

Publications: 14

James H. Woods

James H. Woods

University of Michigan–Ann Arbor

Publications: 14

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Minh Tho Nguyen

KU Leuven

Publications: 13

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Publications: 13

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