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Biology and Biochemistry

D-Index
57
Citations
9630
World Ranking
14032
National Ranking
5919

Overview

Vivek M. Rangnekar is affiliated with the University of Kentucky in the United States and works primarily within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their published research spans a total of 51 publications across these interdisciplinary areas, with an emphasis on Molecular Biology, Pulmonary and Respiratory Medicine, Cancer Research, Oncology, and Genetics as core subfields of study.

Their recent scholarly contributions include several papers focused on cancer biology, disease mechanisms, and therapeutic approaches. Notable publications comprise:

  • Integration of pan-omics technologies and three-dimensional in vitro tumor models: an approach toward drug discovery and precision medicine, 2024, Molecular Cancer
  • Integration of liquid biopsy and pharmacogenomics for precision therapy of EGFR mutant and resistant lung cancers, 2022, Molecular Cancer
  • Peroxiredoxin IV plays a critical role in cancer cell growth and radioresistance through the activation of the Akt/GSK3 signaling pathways, 2022, Journal of Biological Chemistry
  • Ru(II)/amino acid complexes inhibit the progression of breast cancer cells through multiple mechanism-induced apoptosis, 2021, Journal of Inorganic Biochemistry
  • Par-4 regulates autophagic cell death in human cancer cells via upregulating p53 and BNIP3, 2020, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Their research topics encompass a diverse range of cancer-related themes and molecular mechanisms with particular attention to:

  • Lung Cancer Treatments and Mutations
  • Cancer Genomics and Diagnostics
  • Redox Biology and Oxidative Stress
  • Cell Death Mechanisms and Regulation
  • RNA Modifications and Cancer
  • Prostate Cancer Treatment and Research
  • Cancer, Lipids, and Metabolism

Regular collaboration is evident through frequent co-authorship with several other researchers, including:

  • Ravshan Burikhanov (8 joint publications)
  • Mahadev Rao (6 joint publications)
  • Na Ding (3 joint publications)
  • Hong Jiang (3 joint publications)
  • Pratik Thapa (3 joint publications)

Vivek M. Rangnekar has published extensively in journals such as Cells, Molecular Cancer, Journal of Clinical Oncology, Cancer Research, and Journal of Biological Chemistry. The distribution highlights a consistent presence in both specialized cancer journals and broader molecular biology venues.

Best Publications

  • The Cyclooxygenase-2 Inhibitor Celecoxib Induces Apoptosis by Blocking Akt Activation in Human Prostate Cancer Cells Independently of Bcl-2

    Ao Lin Hsu;Tsui Ting Ching;Da Sheng Wang;Xueqin Song

  • Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease.

    Qing Guo;Weiming Fu;Jun Xie;Hong Luo

  • A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1.

    R W Johnstone;R H See;S F Sells;J Wang

  • Suppression of PTEN Expression by NF-κB Prevents Apoptosis

    Krishna Murthi Vasudevan;Sushma Gurumurthy;Vivek M. Rangnekar

  • Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and -independent prostate cells

    S. F. Sells;D. P. Wood;S. S. Joshi-Barve;Sumathi Muthukumar

  • The Tumor Suppressor Par-4 Activates an Extrinsic Pathway for Apoptosis

    Ravshan Burikhanov;Yanming Zhao;Anindya Goswami;Shirley Qiu

  • Expression and function of the leucine zipper protein Par-4 in apoptosis.

    S F Sells;S S Han;S Muthukkumar;N Maddiwar

  • Early growth response-1-dependent apoptosis is mediated by p53.

    Prakash Nair;Sumathi Muthukkumar;Stephen F. Sells;Seong-Su Han

  • Identification of bone marrow micrometastases in patients with prostate cancer

    David P. Wood;Evelyn R. Banks;Evelyn R. Banks;Suzanne Humphreys;J. William McRoberts

  • Binding and Phosphorylation of Par-4 by Akt Is Essential for Cancer Cell Survival

    Anindya Goswami;Ravshan Burikhanov;Aurelie de Thonel;Naoya Fujita

  • Par-4 Drives Trafficking and Activation of Fas and FasL to Induce Prostate Cancer Cell Apoptosis and Tumor Regression

    Mala Chakraborty;Shirley Guofang Qiu;Krishna Murthi Vasudevan;Vivek M. Rangnekar

  • Identification of a unique core domain of Par-4 sufficient for selective apoptosis induction in cancer cells

    Vivek M. Rangnekar

  • Apoptosis by Par-4 in cancer and neurodegenerative diseases.

    Nadia El-Guendy;Vivek M Rangnekar

  • Role of Tumor Necrosis Factor-α and TRAIL in High-Dose Radiation–Induced Bystander Signaling in Lung Adenocarcinoma

    Mohammed M. Shareef;Nuan Cui;Ravshan Burikhanov;Seema Gupta

  • Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter.

    Sangeeta K. Cheema;Sandip K. Mishra;Vivek M. Rangnekar;Ana M. Tari

  • Phosphorylation of Par-4 by protein kinase A is critical for apoptosis.

    Sushma Gurumurthy;Anindya Goswami;Krishna Murthi Vasudevan;Vivek M. Rangnekar

  • Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma

    J. Cook;S. Krishnan;S. Ananth;S. F. Sells

  • Interaction partners of Dlk/ZIP kinase: co-expression of Dlk/ZIP kinase and Par-4 results in cytoplasmic retention and apoptosis.

    Grit Page;Donat Kögel;Vivek Rangnekar;Karl Heinz Scheidtmann

  • ROLE OF EGR-1 IN THAPSIGARGIN-INDUCIBLE APOPTOSIS IN THE MELANOMA CELL LINE A375-C6

    Sumathi Muthukkumar;Prakash Nair;S. F. Sells;N. G. Maddiwar

  • Regulation of apoptosis in prostate cancer

    Sushma Gurumurthy;Krishna Murthi Vasudevan;Vivek M. Rangnekar

Frequent Co-Authors

Chang-Guo Zhan
Chang-Guo Zhan University of Kentucky
Vikas P. Sukhatme
Vikas P. Sukhatme Emory University
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
John C. Byrd
John C. Byrd University of Pittsburgh Cancer Institute
Daret K. St. Clair
Daret K. St. Clair University of Kentucky
Craig Horbinski
Craig Horbinski Northwestern University
Webster K. Cavenee
Webster K. Cavenee University of California, San Diego
Akira Watanabe
Akira Watanabe Kyoto University
Kojo S.J. Elenitoba-Johnson
Kojo S.J. Elenitoba-Johnson Memorial Sloan Kettering Cancer Center
Frank B. Furnari
Frank B. Furnari University of California, San Diego

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