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Biology and Biochemistry

D-Index
73
Citations
19206
World Ranking
5930
National Ranking
425

Overview

Carsten Culmsee is affiliated with Philipp University of Marburg in Germany. Their research broadly spans the fields of Biochemistry, Genetics and Molecular Biology as well as Medicine, with significant contributions to Molecular Biology, Pulmonary and Respiratory Medicine, Cancer Research, Neurology, and Nutrition and Dietetics.

The scientist's work focuses on several interconnected topics, including:

  • Ferroptosis and cancer prognosis
  • Mitochondrial Function and Pathology
  • RNA modifications and cancer
  • Pharmaceutical Practices and Patient Outcomes
  • Cancer, Lipids, and Metabolism
  • Genomics, phytochemicals, and oxidative stress
  • RNA Research and Splicing

Frequent publication venues for their work include:

  • Cell Death and Disease
  • Antioxidants
  • International Journal of Molecular Sciences
  • Frontiers in Pharmacology
  • bioRxiv (Cold Spring Harbor Laboratory)

Some recent papers authored by Carsten Culmsee are:

  • "RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury" (2021, Acta Neuropathologica Communications)
  • "Exogenous Alpha-Synuclein Evoked Parkin Downregulation Promotes Mitochondrial Dysfunction in Neuronal Cells. Implications for Parkinson's Disease Pathology" (2021, Frontiers in Aging Neuroscience)
  • "Mitochondrial Reactive Oxygen Species Formation Determines ACSL4/LPCAT2-Mediated Ferroptosis" (2023, Antioxidants)
  • "SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans" (2020, Cell Death and Disease)
  • "Dynasore Blocks Ferroptosis through Combined Modulation of Iron Uptake and Inhibition of Mitochondrial Respiration" (2020, Cells)

Carsten Culmsee has collaborated frequently with a number of researchers, including:

  • Amalia M. Dolga
  • Georg Boonen
  • Madeline Günther
  • Christoph Rummel
  • Jürgen Drewe

Best Publications

  • Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

    Alexander Seiler;Manuela Schneider;Heidi Förster;Stephan Roth

  • Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity

    Inna I. Kruman;Carsten Culmsee;Sic L. Chan;Yuri Kruman

  • Roles of Nuclear Factor κB in Neuronal Survival and Plasticity

    Mark P. Mattson;Carsten Culmsee;ZaiFang Yu;Simonetta Camandola

  • Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer.

    Sabine Boeckle;Katharina von Gersdorff;Silke van der Piepen;Carsten Culmsee

  • A Dual Role for the SDF-1/CXCR4 Chemokine Receptor System in Adult Brain: Isoform-Selective Regulation of SDF-1 Expression Modulates CXCR4-Dependent Neuronal Plasticity and Cerebral Leukocyte Recruitment after Focal Ischemia

    Ralf K. Stumm;Jutta Rummel;Vera Junker;Carsten Culmsee

  • p53 in neuronal apoptosis.

    Carsten Culmsee;Mark P. Mattson

  • Apoptotic and antiapoptotic mechanisms in stroke

    Mark P. Mattson;Carsten Culmsee;Zai Fang Yu

  • Apoptosis-Inducing Factor Triggered by Poly(ADP-Ribose) Polymerase and Bid Mediates Neuronal Cell Death after Oxygen-Glucose Deprivation and Focal Cerebral Ischemia

    Carsten Culmsee;Changlian Zhu;Stefan Landshamer;Barbara Becattini

  • Neurodegenerative disorders and ischemic brain diseases.

    M. P. Mattson;W. Duan;W. A. Pedersen;C. Culmsee

  • Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases.

    Mark P. Mattson;Ward A. Pedersen;Wenzhen Duan;Carsten Culmsee

  • Transforming Growth Factor-β1 Increases Bad Phosphorylation and Protects Neurons Against Damage

    Yuan Zhu;Guo-Yuan Yang;Barbara Ahlemeyer;Li Pang

  • AMP-activated protein kinase is highly expressed in neurons in the developing rat brain and promotes neuronal survival following glucose deprivation.

    Carsten Culmsee;Jennifer Monnig;Bruce E. Kemp;Mark P. Mattson;Mark P. Mattson;Mark P. Mattson

  • A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

    Carsten Culmsee;Xiaoxiang Zhu;Qian Sheng Yu;Sic L. Chan

  • Inhibition of Drp1 provides neuroprotection in vitro and in vivo.

    Grohm J;Kim Sw;Mamrak U;Tobaben S

  • BID links ferroptosis to mitochondrial cell death pathways

    Sandra Neitemeier;Anja Jelinek;Vincenzo Laino;Lena Hoffmann

  • Mitochondrial rescue prevents glutathione peroxidase-dependent ferroptosis.

    Anja Jelinek;Lukas Heyder;Michael Daude;Matthias Plessner

  • Parkin Mediates Neuroprotection through Activation of IκB Kinase/Nuclear Factor-κB Signaling

    Iris H. Henn;Lena Bouman;Julia S. Schlehe;Anita Schlierf

  • Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia.

    Changlian Zhu;Xiaoyang Wang;Xiaoyang Wang;Z. Huang;Z. Huang;L. Qiu;L. Qiu

  • Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons

    S Tobaben;J Grohm;A Seiler;M Conrad

  • Nuclear Translocation of Apoptosis-Inducing Factor after Focal Cerebral Ischemia:

    Nikolaus Plesnila;Changlian Zhu;Changlian Zhu;Carsten Culmsee;Moritz Gröger

Frequent Co-Authors

Josef Krieglstein
Josef Krieglstein University of Münster
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Changlian Zhu
Changlian Zhu University of Gothenburg
Ernst Wagner
Ernst Wagner Ludwig-Maximilians-Universität München
Günter U. Höglinger
Günter U. Höglinger Ludwig Maximilian University of Munich
Klas Blomgren
Klas Blomgren Karolinska Institute
Martina Schmidt
Martina Schmidt Johannes Gutenberg University of Mainz
Richard Dodel
Richard Dodel University of Duisburg-Essen
Xiaoyang Wang
Xiaoyang Wang University of Gothenburg
Markus Wöhr
Markus Wöhr Philipp University of Marburg

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