Manfred Ogris

Overview

Best Publications

• PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

  M Ogris;S Brunner;S Schüller;R Kircheis

  1537
  Citations

• The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells.

  M Ogris;P Steinlein;M Kursa;K Mechtler

  775
  Citations

• Polylysine-based transfection systems utilizing receptor-mediated delivery.

  Wolfgang Zauner;Manfred Ogris;Ernst Wagner

  695
  Citations

• Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer.

  Sabine Boeckle;Katharina von Gersdorff;Silke van der Piepen;Carsten Culmsee

  554
  Citations

• Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery

  R Kircheis;A Kichler;G Wallner;M Kursa

  528
  Citations

• Polycation-based DNA complexes for tumor-targeted gene delivery in vivo.

  Ralf Kircheis;Susanne Schüller;Sylvia Brunner;Manfred Ogris

  513
  Citations

• Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer.

  Malgorzata Kursa;Greg F Walker;Vanessa Roessler;Manfred Ogris

  412
  Citations

• Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo.

  Greg F. Walker;Carolin Fella;Jaroslav Pelisek;Julia Fahrmeir

  390
  Citations

• Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes.

  Manfred Ogris;Greg Walker;Thomas Blessing;Ralf Kircheis

  389
  Citations

• The Internalization Route Resulting in Successful Gene Expression Depends on both Cell Line and Polyethylenimine Polyplex Type

  Katharina von Gersdorff;Niek N. Sanders;Roosmarijn Vandenbroucke;Stefaan C. De Smedt

  377
  Citations

• Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation

  David Oupicky;Manfred Ogris;Kenneth A. Howard;Philip R. Dash

  373
  Citations

• Peptide-mediated RNA delivery: a novel approach for enhanced transfection of primary and post-mitotic cells

  Thierry Bettinger;Robert C. Carlisle;Martin L. Read;Manfred Ogris

  373
  Citations

• Melittin enables efficient vesicular escape and enhanced nuclear access of nonviral gene delivery vectors.

  Manfred Ogris;Robert C. Carlisle;Thierry Bettinger;Leonard W. Seymour

  304
  Citations

• DNA/polyethylenimine transfection particles: Influence of ligands, polymer size, and PEGylation on internalization and gene expression

  Manfred Ogris;Peter Steinlein;Sebastian Carotta;Sylvia Brunner

  282
  Citations

• Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

  Mohamed Elgendy;Marco Cirò;Amir Hosseini;Jakob Weiszmann

  254
  Citations

• Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate.

  Martin Meyer;Christian Dohmen;Alexander Philipp;Daniel Kiener

  235
  Citations

• Targeting tumors with non-viral gene delivery systems.

  Manfred Ogris;Ernst Wagner

  232
  Citations

• Cellular dynamics of EGF receptor-targeted synthetic viruses.

  Karla de Bruin;Nadia Ruthardt;Katharina von Gersdorff;Ralf Bausinger

  222
  Citations

• Liposome based systems for systemic siRNA delivery: stability in blood sets the requirements for optimal carrier design.

  Kevin Buyens;Stefaan C. De Smedt;Kevin Braeckmans;Joseph Demeester

  206
  Citations

• Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes.

  Sabine Boeckle;Julia Fahrmeir;Wolfgang Roedl;Manfred Ogris

  180
  Citations