His scientific interests lie mostly in Transfection, Gene delivery, Polyethylenimine, Molecular biology and Biochemistry. His research integrates issues of Epidermal growth factor and Genetic transfer in his study of Transfection. His work in Gene delivery tackles topics such as DNA which are related to areas like In vitro.
His Molecular biology research includes themes of HeLa, Gene expression and Cell biology. His study in the field of Transferrin and Receptor-mediated endocytosis also crosses realms of Conjugate. His Biophysics research incorporates themes from Polylysine and Polyethylene glycol.
Transfection, Gene delivery, Molecular biology, Polyethylenimine and Cancer research are his primary areas of study. His Transfection study is concerned with the larger field of Biochemistry. His research investigates the connection between Gene delivery and topics such as Stereochemistry that intersect with issues in Biocompatibility.
His study in Molecular biology is interdisciplinary in nature, drawing from both Reporter gene, Gene expression, Transgene, Receptor and Cell biology. Manfred Ogris interconnects Size-exclusion chromatography, HeLa, Polyethylene glycol, PEGylation and Zeta potential in the investigation of issues within Polyethylenimine. His biological study spans a wide range of topics, including Cancer, Targeted therapy, Genetic enhancement and Pathology.
His primary areas of study are Nucleic acid, Cancer research, Gene delivery, In vitro and Luciferase. His work deals with themes such as Internalization and Genetic enhancement, which intersect with Cancer research. His In vitro research is classified as research in Biochemistry.
His Luciferase study improves the overall literature in Transfection. His work carried out in the field of Transfection brings together such families of science as Transferrin, Receptor, Epidermal growth factor, HeLa and Flow cytometry. His Molecular biology study incorporates themes from Polyethylenimine and Peptide.
The scientist’s investigation covers issues in Biodistribution, Gene delivery, Sodium-iodide symporter, Genetic enhancement and Cancer research. His Biodistribution research is multidisciplinary, incorporating perspectives in Radionuclide therapy, Molecular biology, Transduction, Receptor expression and PLGA. Manfred Ogris integrates many fields, such as Gene delivery and Pancreatic ductal adenocarcinoma, in his works.
In his articles, Manfred Ogris combines various disciplines, including Sodium-iodide symporter and Cancer.
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PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
M Ogris;S Brunner;S Schüller;R Kircheis.
Gene Therapy (1999)
The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells.
M Ogris;P Steinlein;M Kursa;K Mechtler.
Gene Therapy (1998)
Polylysine-based transfection systems utilizing receptor-mediated delivery.
Wolfgang Zauner;Manfred Ogris;Ernst Wagner.
Advanced Drug Delivery Reviews (1998)
Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer.
Sabine Boeckle;Katharina von Gersdorff;Silke van der Piepen;Carsten Culmsee.
Journal of Gene Medicine (2004)
Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery
R Kircheis;A Kichler;G Wallner;M Kursa.
Gene Therapy (1997)
Polycation-based DNA complexes for tumor-targeted gene delivery in vivo.
Ralf Kircheis;Susanne Schüller;Sylvia Brunner;Manfred Ogris.
Journal of Gene Medicine (1999)
Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer.
Malgorzata Kursa;Greg F. Walker;Vanessa Roessler;Manfred Ogris.
Bioconjugate Chemistry (2003)
Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes.
Manfred Ogris;Greg Walker;Thomas Blessing;Ralf Kircheis.
Journal of Controlled Release (2003)
Importance of lateral and steric stabilization of polyelectrolyte gene delivery vectors for extended systemic circulation
David Oupicky;Manfred Ogris;Kenneth A. Howard;Philip R. Dash.
Molecular Therapy (2002)
Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo.
Greg F. Walker;Carolin Fella;Jaroslav Pelisek;Julia Fahrmeir.
Molecular Therapy (2005)
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