World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
49662
World Ranking
11070
National Ranking
850

Overview

Sovan Sarkar is affiliated with the University of Birmingham in the United Kingdom and specializes in research within the fields of biochemistry, genetics, molecular biology, and medicine. Their research focus spans several subfields including molecular biology, epidemiology, physiology, geriatrics and gerontology, and cell biology.

The scientist's work covers various main topics, notably:

  • Autophagy in Disease and Therapy
  • Sirtuins and Resveratrol in Medicine
  • CRISPR and Genetic Engineering
  • Calcium signaling and nucleotide metabolism
  • Mitochondrial Function and Pathology
  • Endoplasmic Reticulum Stress and Disease
  • Pluripotent Stem Cells Research

Sarkar has contributed to multiple scholarly articles, with notable recent papers including:

  • The autophagy-NAD axis in longevity and disease, 2023, Trends in Cell Biology
  • Autophagy promotes cell survival by maintaining NAD levels, 2022, Developmental Cell
  • Trehalose limits opportunistic mycobacterial survival during HIV co-infection by reversing HIV-mediated autophagy block, 2020, Autophagy
  • NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency, 2023, Cell Reports
  • Autophagy in Rare (NonLysosomal) Neurodegenerative Diseases, 2020, Journal of Molecular Biology

The scientist frequently publishes in journals such as the Journal of Molecular Biology, Methods in Molecular Biology, bioRxiv (Cold Spring Harbor Laboratory), Autophagy, and Stem Cell Reports.

Collaborations are a notable aspect of Sarkar's research, with frequent co-authors including Congxin Sun, Viktor I. Korolchuk, Tetsushi Kataura, Elena Seranova, and Timothy Barrett.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Regulation of Mammalian Autophagy in Physiology and Pathophysiology

    Brinda Ravikumar;Sovan Sarkar;Janet E. Davies;Marie Futter

  • Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein

    Sovan Sarkar;Janet E. Davies;Zebo Huang;Alan Tunnacliffe

  • Lithium induces autophagy by inhibiting inositol monophosphatase

    Sovan Sarkar;R. Andres Floto;Zdenek Berger;Sara Imarisio

  • Lysosomal positioning coordinates cellular nutrient responses

    Viktor I. Korolchuk;Shinji Saiki;Maike Lichtenberg;Farah H. Siddiqi

  • Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

    Andrea Williams;Sovan Sarkar;Paul Cuddon;Evangelia K Ttofi

  • Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

    Gaurav Sahay;William Querbes;Christopher Alabi;Ahmed Eltoukhy

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The Aspergillus PacC zinc finger transcription factor mediates regulation of both acid- and alkaline-expressed genes by ambient pH.

    J Tilburn;S Sarkar;D A Widdick;E A Espeso

  • Small molecules enhance autophagy and reduce toxicity in Huntington's disease models

    Sovan Sarkar;Ethan O Perlstein;Ethan O Perlstein;Sara Imarisio;Sandra Pineau

  • In search of an "autophagomometer".

    David C. Rubinsztein;Ana Maria Cuervo;Brinda Ravikumar;Sovan Sarkar

  • Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

    S Sarkar;B Ravikumar;R A Floto;D C Rubinsztein

  • SETD2-Dependent Histone H3K36 Trimethylation Is Required for Homologous Recombination Repair and Genome Stability

    Sophia X. Pfister;Sara Ahrabi;Lykourgos-Panagiotis Zalmas;Sovan Sarkar

  • Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.

    Sovan Sarkar

  • Complex Inhibitory Effects of Nitric Oxide on Autophagy

    Sovan Sarkar;Viktor I. Korolchuk;Maurizio Renna;Sara Imarisio

  • A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin

    Sovan Sarkar;Gauri Krishna;Sara Imarisio;Shinji Saiki

  • Hydrophilic protein associated with desiccation tolerance exhibits broad protein stabilization function

    Sohini Chakrabortee;Chiara Boschetti;Laura J. Walton;Sovan Sarkar

  • Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications.

    Andrea Williams;Luca Jahreiss;Sovan Sarkar;Shinji Saiki

Frequent Co-Authors

David C. Rubinsztein
David C. Rubinsztein University of Cambridge
Viktor I. Korolchuk
Viktor I. Korolchuk Newcastle University
Sergio Lavandero
Sergio Lavandero University of Chile
Cahir J. O'Kane
Cahir J. O'Kane University of Cambridge
Evelina Gatti
Evelina Gatti Aix-Marseille University
Steven Finkbeiner
Steven Finkbeiner University of California, San Francisco
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Patricia Boya
Patricia Boya Spanish National Research Council
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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