2023 - Research.com Medicine in United States Leader Award
2023 - Research.com Molecular Biology in United States Leader Award
2022 - Research.com Best Scientist Award
2010 - US President's National Medal of Science "For improving our understanding of epigenetic regulation of gene expression: the biological mechanisms that affect how genetic information is variably expressed. His work has led to major advances in our understanding of mammalian cloning and embryonic stem cells.", Presented by President Barack H. Obama in the East Room of the White House on Friday, October 21, 2011.
2003 - Member of the National Academy of Sciences
2002 - Robert Koch Prize
2001 - Gruber Prize in Genetics
1992 - Fellow of the American Academy of Arts and Sciences
Rudolf Jaenisch mainly focuses on Genetics, Cell biology, Molecular biology, Embryonic stem cell and Induced pluripotent stem cell. His work carried out in the field of Cell biology brings together such families of science as Cancer research, Transgene, Transcription factor, Mutant and Ectopic expression. The concepts of his Molecular biology study are interwoven with issues in DNA hypomethylation, Gene expression, DNA methyltransferase, DNA methylation and RNA.
His DNA methylation study combines topics in areas such as Carcinogenesis and Methylation. His Embryonic stem cell research integrates issues from Cloning, Stem cell, Cellular differentiation and Somatic cell. The study incorporates disciplines such as Reprogramming and Transplantation in addition to Induced pluripotent stem cell.
Rudolf Jaenisch spends much of his time researching Cell biology, Molecular biology, Genetics, Embryonic stem cell and Gene. His Cell biology research includes themes of Immunology, Reprogramming, Cellular differentiation and Induced pluripotent stem cell. The Induced pluripotent stem cell study combines topics in areas such as SOX2, Transcription factor and Cell type.
Within one scientific family, he focuses on topics pertaining to DNA methylation under Molecular biology, and may sometimes address concerns connected to Methylation and Epigenetics. His studies examine the connections between Embryonic stem cell and genetics, as well as such issues in Stem cell, with regards to Adult stem cell and Embryoid body. His Gene research is multidisciplinary, incorporating elements of Virus and Virology.
His main research concerns Cell biology, Induced pluripotent stem cell, Genetics, Embryonic stem cell and Stem cell. His Cell biology study also includes
Cellular differentiation that intertwine with fields like Molecular biology,
Gene expression, which have a strong connection to In vitro,
Epigenetics which connect with Methylation and Cancer research. His research on Induced pluripotent stem cell also deals with topics like
Reprogramming which connect with Epigenomics,
Progenitor cell and related Virology and Neural stem cell.
Regulation of gene expression and DNA methylation are subfields of Genetics in which his conducts study. His Embryonic stem cell research is multidisciplinary, incorporating perspectives in Immunology and Embryo. His Stem cell study which covers Bioinformatics that intersects with Stem cell marker.
Rudolf Jaenisch mainly investigates Induced pluripotent stem cell, Cell biology, Genetics, Embryonic stem cell and Reprogramming. His Induced pluripotent stem cell research is multidisciplinary, relying on both Viability assay, Epigenesis, Computational biology and Cell type. His research in Cell biology intersects with topics in Genome, Epigenetics, Cellular differentiation and DNA methylation.
In his research on the topic of Embryonic stem cell, Embryo and Transcription is strongly related with X chromosome. His biological study spans a wide range of topics, including SOX2, LIN28, Transcription factor, Homeobox protein NANOG and Tetraploid complementation assay. His work is dedicated to discovering how Epigenomics, Illumina Methylation Assay are connected with Molecular biology and other disciplines.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
Rudolf Jaenisch;Adrian Bird.
Nature Genetics (2003)
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality.
En Li;Timothy H. Bestor;Rudolf Jaenisch.
A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
Bradley E. Bernstein;Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Xiaohui Xie;Michael Kamal.
Core transcriptional regulatory circuitry in human embryonic stem cells.
Laurie A. Boyer;Tong Ihn Lee;Megan F. Cole;Sarah E. Johnstone.
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
Tarjei S. Mikkelsen;Manching Ku;Manching Ku;David B. Jaffe;Biju Issac;Biju Issac.
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
Mitchell Guttman;Ido Amit;Manuel Garber;Courtney French.
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.
Haoyi Wang;Hui Yang;Chikdu S. Shivalila;Meelad M. Dawlaty.
Histone H3K27ac separates active from poised enhancers and predicts developmental state
Menno P. Creyghton;Albert W. Cheng;G. Grant Welstead;Tristan G. Kooistra.
Proceedings of the National Academy of Sciences of the United States of America (2010)
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
Marius Wernig;Alexander Meissner;Ruth Foreman;Tobias Brambrink.
Role for DNA methylation in genomic imprinting
E. Li;C. Beard;R. Jaenisch.
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