What is he best known for?
The fields of study he is best known for:
Rudolf Jaenisch mainly focuses on Genetics, Cell biology, Molecular biology, Embryonic stem cell and Induced pluripotent stem cell.
His work carried out in the field of Cell biology brings together such families of science as Cancer research, Transgene, Transcription factor, Mutant and Ectopic expression.
The concepts of his Molecular biology study are interwoven with issues in DNA hypomethylation, Gene expression, DNA methyltransferase, DNA methylation and RNA.
His DNA methylation study combines topics in areas such as Carcinogenesis and Methylation.
His Embryonic stem cell research integrates issues from Cloning, Stem cell, Cellular differentiation and Somatic cell.
The study incorporates disciplines such as Reprogramming and Transplantation in addition to Induced pluripotent stem cell.
His most cited work include:
- Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals (4675 citations)
- A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells (4203 citations)
- Core transcriptional regulatory circuitry in human embryonic stem cells. (3708 citations)
What are the main themes of his work throughout his whole career to date?
Rudolf Jaenisch spends much of his time researching Cell biology, Molecular biology, Genetics, Embryonic stem cell and Gene.
His Cell biology research includes themes of Immunology, Reprogramming, Cellular differentiation and Induced pluripotent stem cell.
The Induced pluripotent stem cell study combines topics in areas such as SOX2, Transcription factor and Cell type.
Within one scientific family, he focuses on topics pertaining to DNA methylation under Molecular biology, and may sometimes address concerns connected to Methylation and Epigenetics.
His studies examine the connections between Embryonic stem cell and genetics, as well as such issues in Stem cell, with regards to Adult stem cell and Embryoid body.
His Gene research is multidisciplinary, incorporating elements of Virus and Virology.
He most often published in these fields:
- Cell biology (33.06%)
- Molecular biology (31.13%)
- Genetics (29.84%)
What were the highlights of his more recent work (between 2013-2021)?
- Cell biology (33.06%)
- Induced pluripotent stem cell (18.23%)
- Genetics (29.84%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cell biology, Induced pluripotent stem cell, Genetics, Embryonic stem cell and Stem cell.
His Cell biology study also includes
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Cellular differentiation that intertwine with fields like Molecular biology,
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Gene expression, which have a strong connection to In vitro,
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Epigenetics which connect with Methylation and Cancer research.
His research on Induced pluripotent stem cell also deals with topics like
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Reprogramming which connect with Epigenomics,
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Progenitor cell and related Virology and Neural stem cell.
Regulation of gene expression and DNA methylation are subfields of Genetics in which his conducts study.
His Embryonic stem cell research is multidisciplinary, incorporating perspectives in Immunology and Embryo.
His Stem cell study which covers Bioinformatics that intersects with Stem cell marker.
Between 2013 and 2021, his most popular works were:
- Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells (721 citations)
- Editing DNA Methylation in the Mammalian Genome (596 citations)
- Activation of proto-oncogenes by disruption of chromosome neighborhoods (559 citations)
In his most recent research, the most cited papers focused on:
Rudolf Jaenisch mainly investigates Induced pluripotent stem cell, Cell biology, Genetics, Embryonic stem cell and Reprogramming.
His Induced pluripotent stem cell research is multidisciplinary, relying on both Viability assay, Epigenesis, Computational biology and Cell type.
His research in Cell biology intersects with topics in Genome, Epigenetics, Cellular differentiation and DNA methylation.
In his research on the topic of Embryonic stem cell, Embryo and Transcription is strongly related with X chromosome.
His biological study spans a wide range of topics, including SOX2, LIN28, Transcription factor, Homeobox protein NANOG and Tetraploid complementation assay.
His work is dedicated to discovering how Epigenomics, Illumina Methylation Assay are connected with Molecular biology and other disciplines.
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