World's Best Scientists 2026 revealed!
Konrad Hochedlinger

Konrad Hochedlinger

D-Index & Metrics

Molecular Biology

D-Index
89
Citations
50366
World Ranking
745
National Ranking
401

Overview

Konrad Hochedlinger is affiliated with Harvard University in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. The scientist's work is concentrated on subfields including Molecular Biology, Oncology, Hematology, Immunology, and Surgery.

Hochedlinger's notable research topics include:

  • Pluripotent Stem Cells Research
  • Genomics and Chromatin Dynamics
  • CRISPR and Genetic Engineering
  • Epigenetics and DNA Methylation
  • RNA Research and Splicing
  • RNA Interference and Gene Delivery
  • Cancer-related gene regulation

The scientist has contributed to a number of publications, with frequent appearances in the following venues:

  • Genes & Development
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Cell Biology
  • Stem Cell Reports
  • Nature

Frequent co-authors who have collaborated with Hochedlinger include:

  • Ruslan I. Sadreyev
  • Aaron J. Huebner
  • Alexander Meissner
  • Masaki Yagi
  • Nikolaos Tsopoulidis

Some of the recent papers published by Hochedlinger include:

  • "Reprogramming to recover youthful epigenetic information and restore vision," 2020, Nature
  • "Chromatin-state barriers enforce an irreversible mammalian cell fate decision," 2021, Cell Reports
  • "Dissecting dual roles of MyoD during lineage conversion to mature myocytes and myogenic stem cells," 2021, Genes & Development
  • "NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia," 2022, Nature Immunology
  • "H3K36 methylation maintains cell identity by regulating opposing lineage programmes," 2023, Nature Cell Biology

Best Publications

  • In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

    Marius Wernig;Alexander Meissner;Ruth Foreman;Tobias Brambrink

  • Disease-Specific Induced Pluripotent Stem Cells

    In Hyun Park;Natasha Arora;Hongguang Huo;Nimet Maherali

  • Induced pluripotent stem cells generated without viral integration

    Matthias Stadtfeld;Masaki Nagaya;Masaki Nagaya;Jochen Utikal;Gordon Weir;Gordon Weir

  • Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution

    Nimet Maherali;Rupa Sridharan;Wei Xie;Jochen Utikal

  • Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

    Jose M. Polo;Susanna Liu;Maria Eugenia Figueroa;Warakorn Kulalert

  • Ectopic Expression of Oct-4 Blocks Progenitor-Cell Differentiation and Causes Dysplasia in Epithelial Tissues

    Konrad Hochedlinger;Yasuhiro Yamada;Caroline Beard;Rudolf Jaenisch

  • The Sox Family of Transcription Factors: Versatile Regulators of Stem and Progenitor Cell Fate

    Abby Sarkar;Abby Sarkar;Konrad Hochedlinger;Konrad Hochedlinger

  • Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

    Jochen Utikal;Jose M. Polo;Matthias Stadtfeld;Nimet Maherali

  • Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse

    Matthias Stadtfeld;Nimet Maherali;David T. Breault;David T. Breault;Konrad Hochedlinger

  • Induced pluripotency: history, mechanisms, and applications

    Matthias Stadtfeld;Konrad Hochedlinger

  • A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells

    Jose M. Polo;Endre Anderssen;Endre Anderssen;Ryan M. Walsh;Benjamin A. Schwarz

  • Epigenetic Instability in ES Cells and Cloned Mice

    David Humpherys;Kevin Eggan;Hidenori Akutsu;Konrad Hochedlinger

  • Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

    Matthias Stadtfeld;Effie Apostolou;Hidenori Akutsu;Atsushi Fukuda

  • Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette

    Cesar A. Sommer;Matthias Stadtfeld;George J. Murphy;Konrad Hochedlinger

  • Sox2(+) adult stem and progenitor cells are important for tissue regeneration and survival of mice

    Katrin Arnold;Abby Sarkar;Abby Sarkar;Mary Anna Yram;Mary Anna Yram;Jose M. Polo;Jose M. Polo

  • Monoclonal mice generated by nuclear transfer from mature B and T donor cells

    Konrad Hochedlinger;Rudolf Jaenisch

  • Epigenetic reprogramming and induced pluripotency

    Konrad Hochedlinger;Kathrin Plath

  • Correction of a Genetic Defect by Nuclear Transplantation and Combined Cell and Gene Therapy

    William M. Rideout;Konrad Hochedlinger;Konrad Hochedlinger;Michael Kyba;George Q. Daley;George Q. Daley

  • A high-efficiency system for the generation and study of human induced pluripotent stem cells.

    Nimet Maherali;Tim Ahfeldt;Tim Ahfeldt;Alessandra Rigamonti;Jochen Utikal

  • Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells

    Caroline Beard;Konrad Hochedlinger;Kathrin Plath;Anton Wutz

Frequent Co-Authors

Alexander Meissner
Alexander Meissner Max Planck Institute for Molecular Genetics
George Q. Daley
George Q. Daley Boston Children's Hospital
Peter J. Park
Peter J. Park Harvard University
Jose M. Polo
Jose M. Polo Monash University
Stuart H. Orkin
Stuart H. Orkin Harvard University
Yasuhiro Yamada
Yasuhiro Yamada University of Tokyo
Jochen Utikal
Jochen Utikal German Cancer Research Center
Ruslan I. Sadreyev
Ruslan I. Sadreyev Harvard University
Eric S. Lander
Eric S. Lander Broad Institute

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Molecular Biology in the USA often inspires students to consider broader healthcare and science careers. For those interested in a fast-track medical career, there are several online bsn programs for non nurses that offer an accelerated path into nursing, even for those without a previous nursing background.

Many professionals choose to advance further in nursing, and a popular step is pursuing an RN to BSN degree. Some of the rn to bsn 6 months programs allow registered nurses to complete their bachelor's degree quickly and efficiently.

If your career goals include advanced practice, it’s helpful to know how many years does it take to be a nurse practitioner. The right educational path can significantly shorten the time required to become a certified practitioner.

Specializations like psychiatric nursing are in high demand. To plan for your future, you may want to explore the psychiatric mental health nurse practitioner salary by state, which provides insights on job prospects and earning potential nationwide.

Best Scientists Citing Konrad Hochedlinger

Trending Scientists

Recently Published Articles